Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) ykfI-yfjZ/CbtA-CbeA
Location 1566118..1566843 Replicon chromosome
Accession NZ_CP065178
Organism Pectobacterium quasiaquaticum strain A398-S21-F17

Toxin (Protein)


Gene name ykfI Uniprot ID -
Locus tag IG605_RS07350 Protein ID WP_193408056.1
Coordinates 1566523..1566843 (+) Length 107 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag IG605_RS07345 Protein ID WP_193399492.1
Coordinates 1566118..1566453 (+) Length 112 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IG605_RS07315 (IG605_007300) 1561714..1562769 + 1056 WP_193399487.1 hypothetical protein -
IG605_RS07320 (IG605_007305) 1562865..1563752 + 888 WP_193399488.1 50S ribosome-binding GTPase -
IG605_RS07325 (IG605_007310) 1563936..1564094 + 159 WP_189654467.1 hypothetical protein -
IG605_RS07330 (IG605_007315) 1564241..1565074 + 834 WP_193399489.1 hypothetical protein -
IG605_RS07335 (IG605_007320) 1565132..1565482 + 351 WP_193399490.1 hypothetical protein -
IG605_RS07340 (IG605_007325) 1565605..1566078 + 474 WP_193399491.1 DNA repair protein RadC -
IG605_RS07345 (IG605_007330) 1566118..1566453 + 336 WP_193399492.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
IG605_RS07350 (IG605_007335) 1566523..1566843 + 321 WP_193408056.1 TA system toxin CbtA family protein Toxin
IG605_RS07355 (IG605_007340) 1566961..1567794 + 834 WP_193408057.1 DUF4942 domain-containing protein -
IG605_RS07360 (IG605_007345) 1567888..1568118 + 231 WP_012765080.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein -
IG605_RS07365 (IG605_007350) 1568118..1568546 + 429 WP_193408058.1 tRNA(fMet)-specific endonuclease VapC -
IG605_RS07370 (IG605_007355) 1568839..1570275 - 1437 WP_226373479.1 IS1182 family transposase -
IG605_RS07375 (IG605_007360) 1570541..1570753 - 213 Protein_1413 IS110 family transposase -
IG605_RS07380 (IG605_007365) 1570842..1571105 + 264 Protein_1414 integrase core domain-containing protein -
IG605_RS07385 (IG605_007370) 1571135..1571353 + 219 Protein_1415 IS3 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - hcp 1529760..1578581 48821


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-105)

Antitoxin

Antitoxin CbeA

(7-106)


Sequences

Toxin        


Download         Length: 107 a.a.        Molecular weight: 12003.78 Da        Isoelectric Point: 5.0492

>T182272 WP_193408056.1 NZ_CP065178:1566523-1566843 [Pectobacterium quasiaquaticum]
MQTSPAIPPREDNPCPSPIAVWQQLLTYLLEKHYGLTLNDTPFCEENVIQAHIDAGVTLVNAVNFLVEKYELVRIDRNGF
NWQEQSPFLTAVDVLRARRAIGLLKA

Download         Length: 321 bp

>T182272 NZ_CP086372:3486745-3487668 [Xanthomonas oryzae pv. oryzae]
ATGAACGAACCTGACAAGAGCAGGCGCACTGTTGCCGCGTCGGTTCGCGCCCGGCTGCTCAACAAGGCCCGCGCCGAAAG
ACTCGACTTCAACCTGCTGCTGACCCGCTACGCGCTGGAGCGCGTCCTTTACCGCCTGAGCGTTTCGGAGCAGCAGGGTC
AATTCTTGCTCAAAGGTGCGCTGCTGTTCGACATCTGGTTCGACATACCGCATCGCCCGACGCACGATGCCGACCTGCTG
GGCTTCGGCTCCACCGAGATCCCACATCTGGAAGACCTGTTCCGCAGAATCAGTCAAATCGCCAGCGATGACGGCATCGT
GTTTCAGGCCGACAGCGTGAAGGCCGCCGAAATCCGCAAGGAGGCCAACTACGCGGGCGTCCGTGTGACGATGATCGGCC
TGCTCGATGGCGCGCGCTGCACGGTGCAGATCGACATCGGTTTCGGCGACGCCGTGACGCCCGGCCCGGACAACGTGCAG
TACCCAGTCATCCTCGACGGCATGCCGCAGCCGCAACTGCGGGTCTATCCCCGCTACACCGTGGTCGCCGAAAAGCTGGA
AGCGATGGTCAAGCTCGGCATCCTCAACAGCCGGATGAAGGACTACTTCGACCTCTGGGTTCTCGCCGGACATTCCGACT
TCGACGGTGCGGTGCTGGCCACGGCCATTCGCGCCACGTTCGAGTGCAGGGGTACGGCCATCCCACCCGGCGCGCCGCTG
GGCCTCACCGATGAGTTCGGCCTGGACGAGCAGAAGACAAAGCAGTGGCAGGCGTTCCTGCGCAAGAACACCTTGGAGCC
GATGCCGCTGACCACGGTGATCGAAGCGCTGCGCGAATTCGTGCTGCCCGTGCTGGCCGCGCTCGCGGCAGGCGAAGGTT
TCGACCGCCAGTGGCGCGCGGGCGCGGGATGGGATGCGGCCTGA

Antitoxin


Download         Length: 112 a.a.        Molecular weight: 12433.12 Da        Isoelectric Point: 5.1308

>AT182272 WP_193399492.1 NZ_CP065178:1566118-1566453 [Pectobacterium quasiaquaticum]
MPSSDTPEWGLKCAITRRFGARLVQEGNRLHYLADRASIVGTFSKTEAQSLERCFPELIELLEQKLRMGELNPRQQGGVT
LYCNEWTCEADTLGSVGYVYIVIYPSSAATQ

Download         Length: 336 bp

>AT182272 NZ_CP086372:3486149-3486748 [Xanthomonas oryzae pv. oryzae]
ATGGACACGACCGTCGACAAGCTGCTGGAGCTGGTGCGCACGCGGGGACTTCTGCGCCCGCACGATCTGGCCCCACTGGG
CATCCCACGGGTGGCCCTGACGCGGGCCGTTCGGCGCGGGCAACTGGAGCGCGTCGGGCGCGGCCTGTACGGCCTGGTGG
CGCGTCCGGTGTCGGCCCACGGCACGCTGGCCGAAGTCGCGCGCCGCGTGCCCAAGGGCGTGGTCTGCCTGCTGTCGGCG
CTGCGCGTCCACGACCTGACGACCCAGGCCCCGTTCGAGGTGTGGCTGGCCATCGACAACAAGGCCGCTGCCCCGAAGCT
GGACTACCCGCCGCTACGTCTCGTGCGCTTCTCCGGGCCGGCGCTGAGCGAGGGCGTCGAGGAACACGTTGTTGATGGTG
TGCCCGTCCACGTGACCAGCGTCGCCAAGACCGTGGCCGACTGCTTCAAGTACCGCAACAAGATCGGCATCGACGTGGCG
CTGGAAGCGCTGCGCGAGGCGTGGGTTGCCCGGCGCATGACCAGCGACGAGATCTGGCACTACGCCAAGATCGACCGCGT
CGCCAACGTGATGCGTCCCTATCTGGAGAGCCTGGCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References