Detailed information of TA system TA182271

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): tad-ata/COG5606-COG4679
• Location: 1253544..1254207
• Replicon: chromosome
• Accession: NZ_CP065178
• Organism: Pectobacterium quasiaquaticum strain A398-S21-F17

Toxin (Protein)

• Gene name: tad
• Uniprot ID: -
• Locus tag: IG605_RS05865
• Protein ID: WP_193398732.1
• Coordinates: 1253863..1254207 (-)
• Length: 115 a.a.

Antitoxin (Protein)

• Gene name: ata
• Uniprot ID: -
• Locus tag: IG605_RS05860
• Protein ID: WP_014916192.1
• Coordinates: 1253544..1253861 (-)
• Length: 106 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
IG605_RS05825 (IG605_005815)	1249072..1249950	-	879	WP_193407799.1	aldo/keto reductase family oxidoreductase	-
IG605_RS05830 (IG605_005820)	1249980..1250903	-	924	WP_193401078.1	NADP-dependent oxidoreductase	-
IG605_RS05835 (IG605_005825)	1251022..1251624	+	603	WP_193398779.1	TetR/AcrR family transcriptional regulator	-
IG605_RS05840 (IG605_005830)	1251681..1251908	-	228	WP_226373374.1	hypothetical protein	-
IG605_RS05845 (IG605_005835)	1252229..1252498	+	270	WP_193398733.1	DUF1778 domain-containing protein	-
IG605_RS05850 (IG605_005840)	1252502..1252993	+	492	WP_039498513.1	GNAT family N-acetyltransferase	-
IG605_RS05855 (IG605_005845)	1253242..1253457	+	216	WP_010279992.1	helix-turn-helix transcriptional regulator	-
IG605_RS05860 (IG605_005850)	1253544..1253861	-	318	WP_014916192.1	helix-turn-helix transcriptional regulator	Antitoxin
IG605_RS05865 (IG605_005855)	1253863..1254207	-	345	WP_193398732.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
IG605_RS05870 (IG605_005860)	1254501..1255958	-	1458	WP_193407798.1	sel1 repeat family protein	-
IG605_RS05875 (IG605_005865)	1256064..1257094	-	1031	Protein_1120	helix-turn-helix domain-containing protein	-
IG605_RS05880 (IG605_005870)	1257087..1257818	+	732	WP_226373389.1	alpha/beta hydrolase	-
IG605_RS05885 (IG605_005875)	1257853..1258473	+	621	WP_193407796.1	FMN-dependent NADH-azoreductase	-
IG605_RS05890 (IG605_005880)	1258513..1258821	+	309	WP_193407795.1	YciI family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin HigB-like (12-105)

Antitoxin

• Cro/C1-type helix-turn-helix domain (34-86)

Sequences

Toxin

Protein

• Length: 115 a.a.
• Molecular weight: 12371.12 Da
• Isoelectric Point: 9.7825

>T182271 WP_193398732.1 NZ_CP065178:c1254207-1253863 [Pectobacterium quasiaquaticum]
MKSLYWVGSSKKDLQSLPADVQDVFGYALHVAQTGGKHIQAKPLKGFGGAGVLEVVEDYIGDTYRAVYTVKFGESVYVLH
AFQKKSSSGIATPKPDMNTIRERLKAAENHAKGA

Nucleotide

• Length: 345 bp

>T182271 NZ_CP086372:2102835-2103116 [Xanthomonas oryzae pv. oryzae]
GTGATCAGGAGCTTTATCGACAAGGACGCCGAAAAGATCTGGCTGGGTGAGCGTTCCCGCCGGTTGCCTGCCGACATCCA
ATTGGTCGCGCGCCGCAAGTTGCGCATGCTCAATGCCGCCGCACATCTCGACGATCTGCGGATCCCGCCCGCCAACCGGC
TGGAAGCGTTGAAGGGCCAGCGGCGCGGCCAGTACAGCATCCGGATCAACGATCAATGGCGCATCTGCTTCCGATGGATG
GAAGGCGATGTGGTCCAGGTCGAAATCGTCGATTACCACTGA

Antitoxin

Protein

• Length: 106 a.a.
• Molecular weight: 11434.45 Da
• Isoelectric Point: 10.6133

>AT182271 WP_014916192.1 NZ_CP065178:c1253861-1253544 [Pectobacterium quasiaquaticum]
MSQDIEVSSGNVYADLGNVHAEDMLVKAQLATLISSIIKSRRLTQAEAAKLLGMPQPKLSNLLRGQFRGISETKMLECLT
KLGRDIQIVVGKPRRTPGSVKVVFA

Nucleotide

• Length: 318 bp

>AT182271 NZ_CP086372:2103134-2103424 [Xanthomonas oryzae pv. oryzae]
ATGACGGTCCTACCCAATATCCATCCTGGCGACATTCTGCTTGAGGAGTTTCTCGAGCCTCTGGGCATCAGCCAGAATGC
ACTGGCACGCGCCACCGGCGTCCCGCCGCGCCGTATCAACGAAATCGTGCTGGGCAAGCGCGGCATCACTGCCGACACTG
CCGTGCGTCTGGCCGCCGCGTTGGGCACCTCCGAGCGCTTCTGGCTGGGCCTGCAGGCCGACTACGAGCTGGAACAGGCG
CATCGCGCGCTGGGCGATTTGCCGGCACGGATCAAGCGGCTGGCGGCGTGA