Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/ParE-RHH
Location 463779..464362 Replicon chromosome
Accession NZ_CP065178
Organism Pectobacterium quasiaquaticum strain A398-S21-F17

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag IG605_RS02220 Protein ID WP_193397854.1
Coordinates 464057..464362 (+) Length 102 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A7V8PT23
Locus tag IG605_RS02215 Protein ID WP_010296210.1
Coordinates 463779..464069 (+) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IG605_RS02195 (IG605_002185) 458913..460175 - 1263 WP_014913996.1 L-rhamnose isomerase -
IG605_RS02200 (IG605_002190) 460172..461662 - 1491 WP_193407647.1 rhamnulokinase -
IG605_RS02205 (IG605_002195) 461999..462838 + 840 WP_193397852.1 HTH-type transcriptional activator RhaS -
IG605_RS02210 (IG605_002200) 462863..463717 + 855 WP_193407648.1 helix-turn-helix domain-containing protein -
IG605_RS02215 (IG605_002205) 463779..464069 + 291 WP_010296210.1 ribbon-helix-helix protein, CopG family Antitoxin
IG605_RS02220 (IG605_002210) 464057..464362 + 306 WP_193397854.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
IG605_RS02225 (IG605_002215) 464422..466131 - 1710 WP_193407649.1 ABC transporter ATP-binding protein -
IG605_RS02230 (IG605_002220) 466128..466994 - 867 WP_193407650.1 ABC transporter permease -
IG605_RS02235 (IG605_002225) 466987..467946 - 960 WP_193407651.1 ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-96)

Antitoxin

Ribbon-helix-helix protein, CopG

(9-46)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11606.46 Da        Isoelectric Point: 9.4385

>T182267 WP_193397854.1 NZ_CP065178:464057-464362 [Pectobacterium quasiaquaticum]
MPQVIVSERAKRDLQRLQDFLKNKNALAAKKAAEVLIRGIRQLEALPNIGRPVEHLPLEYQELVIEFGSSGYVMLYRHDE
LTDRVVILTVKHQKEAGYQNP

Download         Length: 306 bp

>T182267 NZ_CP086370:6719438-6720361 [Massilia sp. HC52]
ATGAACTTTGCCGGCATCAGCGCCAAGGCACCGGAAGCGGACGGCTTGCAGTACGCCCTGTCCCTGCTGGAGCGCCATTT
CGCGGAGCAGACCGTGGCCGTCGAAGGCGGCGCCGTGAGCTACCGCGAGATCGCTCCGGCGCCGGGCGTGCCGCCTGCGC
CAGCCACGCAGTCTGCCATTGTGCTCTTGCACGGCATAGGCTCGGGCGCCGCCTCCTGGCTGCCTTGCGCGCTGGAGCTG
GCAGCCGCCGCGCCGGGCGCGCGCATCATCGCCTGGAACGCACCCGGCTACGGCGCTTCCACGCCGCTGCCCGCCGCACG
TCCCGGCGCGGACGCCTACGCAGCCCGCCTGCGCCAGATGCTGCAGGCCCTGGGCGTGCTGGGCGCGCACGACAGCGGCC
GCATCACGCTGGTGGGCCATTCGCTGGGCGCCATGATGGCGTCCGCCTACGCGGCGGCCCATCCGGCCACGCTGGACAAG
CTGGTGCTGCTCAGCCCAGCGCGCGGCTACGGCCAGGCGGCGCGGCTGGAGCAAGGTGCGCAAGTGGCCCGCGAACGCCT
GTCCACCGTGGGCGAGCTGGGCGTGCATGGCATGGCCACGCAGCGCTCGGCCCGCCTCCTGTCCGGCAACGCCACCACCG
CGCAGCGCGACTGGGTGCGCTGGAATATGGCGCAGCTGAACCTGGCCGGCTACACGCAGGCGGTGCATCTGCTGTGCGGC
GACGCCATCGAGAACTACGCGCTGTCCGGCGCCGTGTGCGCAGTGGCCTCGGTCCACTGCGGCAGCGCCGACAACGTCAC
CACGCCGGACGACTGCCGCCTGGTGGCGGAGCGCCACGGCCTGCCCTTCGCACTGATAGACCAGGCCGGCCACGCCTGCT
ACGTGGAGCAGCCATCCGCTGCCATGGCCGCCATCCTGAACTGA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 11064.13 Da        Isoelectric Point: 4.7692

>AT182267 WP_010296210.1 NZ_CP065178:463779-464069 [Pectobacterium quasiaquaticum]
MADTTRQTTTLRIDQDIKERLKTLADDRNSSAHALMLEAIAEYVEREEKRSQYRKEALAAWEDYQDTGKHITADETVTWL
ESWGSGHEQDAPACHK

Download         Length: 291 bp

>AT182267 NZ_CP086370:6720387-6721223 [Massilia sp. HC52]
ATGAACAACAAGCCTGAACAAGCGGAAGACGACAGCGCCGACAAATACACGGTGCCCGGCCTGGAACGCGGCCTGCGCCT
GCTGTGCGAATTCAGCCGCAACGAGAAGACCTTGTCCGCGCCGGAACTGGCCAAGCGCCTGGACGTGCCGCGTTCCACCG
TGTTCCGCCTGCTGACCACACTGGAGCGCATGGGCTTCGTCGAACGCGCCGAGGGCGGCCGCGACTACCGCCTCGGCATG
GCCGTGCTGCGCATGGGCTTTGAATACCTGGCCTCGCTGGAGCTGACCGAAATCGGCCGCCCGCTGCTCGAGCGCCTGCG
CGACGAAATCGGCTACTCCACCACGCTGGTGGTGCGCGACGCGCGCAACATCGTCTACGTGGCCAAGTCCAGCACCCCGG
CGCCGTTCGTCAGCACCGTCAACGTCGGCACCCGCCTGCCGGCCCATGCCACGGTGCTGGGCCGCGTGCTGCTGCAGGAC
CTGACCCTGCCGCAGTTGCGCGAGCTGTATCCGGAAGAGCACCTGAAGGTGTATTCGGACAGCACGCCGCACACCGTGCT
GGACCTGTTCAACCTGCTGCAGCAGGACCGCGAGCGCGGCTACGTGTGGGAGCAGGGCTTCTTCGAGCGCGGCATTTCCA
CCATGGCCGCGCCGGTGCGCGACCACAGCGGCAAGGTCGTCGCCGCGCTGGGCGCCACCATCCCCGACCAGAACATCGGC
GGCGAACAGCTGGAGCGCATCGTGGCCCAGGTGCGCGGCAGCGCAGGCGAGCTTTCGCGCCTGCTGGACCACGCGCCGAC
CGAGACCGCGCAAATCGTCAACCTCTGGCAGCGTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A7V8PT23

References