182266

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) stbDE/ParE-DnaT
Location 361805..362336 Replicon chromosome
Accession NZ_CP065178
Organism Pectobacterium quasiaquaticum strain A398-S21-F17

Toxin (Protein)


Gene name stbE Uniprot ID A0A086EVU3
Locus tag IG605_RS01735 Protein ID WP_039282785.1
Coordinates 362049..362336 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name stbD Uniprot ID A0A1V2R9J2
Locus tag IG605_RS01730 Protein ID WP_039282788.1
Coordinates 361805..362059 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IG605_RS01705 (IG605_001695) 356914..357504 - 591 WP_005975525.1 DnaA initiator-associating protein DiaA -
IG605_RS01710 (IG605_001700) 357546..357902 - 357 WP_193397224.1 YraN family protein -
IG605_RS01715 (IG605_001705) 357899..359917 - 2019 WP_193408016.1 penicillin-binding protein activator -
IG605_RS01720 (IG605_001710) 359981..360868 + 888 WP_039470360.1 16S rRNA (cytidine(1402)-2'-O)-methyltransferase -
IG605_RS01730 (IG605_001720) 361805..362059 + 255 WP_039282788.1 plasmid stabilization protein Antitoxin
IG605_RS01735 (IG605_001725) 362049..362336 + 288 WP_039282785.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
IG605_RS01740 (IG605_001730) 362513..363298 + 786 WP_039524247.1 4,5-DOPA dioxygenase extradiol -
IG605_RS01745 (IG605_001735) 363558..364718 - 1161 WP_193397176.1 glutathionylspermidine synthase family protein -
IG605_RS01750 (IG605_001740) 364730..365404 - 675 WP_193397175.1 DUF1190 family protein -
IG605_RS01755 (IG605_001745) 365674..367068 - 1395 WP_193397174.1 outer membrane channel protein TolC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-86)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11011.96 Da        Isoelectric Point: 10.7694

>T182266 WP_039282785.1 NZ_CP065178:362049-362336 [Pectobacterium quasiaquaticum]
MTYKLKFVPSAMKEWKKLGHPVREQFKKKLVERLENPRVPSAQLHGRKDQYKIKLKSAGYRLVYLVQDETITVMVMGVGK
REGSQIYSDTKGRSA

Download         Length: 288 bp

>T182266 NZ_CP086370:5017406-5017807 [Massilia sp. HC52]
ATGCCGCTCTACATGCTGGATACCAATATGTGTATCTATCTCATGAAGAATCAGCCAGCACAGGTCTCGGAACGATTTTC
TCAATGCTATGTCGGCGACGTCGTGATGTCCGCGATTACTTATGCCGAGTTGGAATATGGTGTTGAGATTTCAGCCAACA
GCATGCGAGAACGACGAAATCTTGCAGCGCTGGTTGAAGACATTCCTGTTGCGGCTTTCAATATGGCCGCAGCAAAAGCC
TATGGCCCAGTTCGAGCCGCGGCCAGAGAGAGGAAAAGGGATCAGCTCGACAAACTGATTGCAGCGCATGCAATCGCGCT
CGATGTCATCCTCGTCACCAACAACGAGAAAGACTTTGCCAGATACCCAAGTTTGAAAATGGAGAACTGGTTGCGTATCT
GA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9208.38 Da        Isoelectric Point: 3.7947

>AT182266 WP_039282788.1 NZ_CP065178:361805-362059 [Pectobacterium quasiaquaticum]
MAFNILTNTAASITELKRDPMGTVRAAEGETIAILNRNEPAFYCVPPAVFAYLMELAEDAELGRTVDDRMSELADAEEIS
LDDL

Download         Length: 255 bp

>AT182266 NZ_CP086370:5017170-5017406 [Massilia sp. HC52]
ATGAAGACGACCAAACTCTTCCGAAACGGCAATTCGCAGGCCGTGCGCATCCCATCGGAACTGGCCTACGAGCGCACGGA
TATGGAGTTGGAAATAGAGCGGGTGGGCGAAGAGTTGCGTATCCGCCCAGCCCGTAGGCCGCTCACTGGTGTGCTGAAGA
AGTTTGCACGGTTTGGCCCGGATTTCATGTCTGAAGGACGAGGCGATCAAGAGCAGGCCGAGCGGGAACCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A086EVU3

Antitoxin

Source ID Structure
AlphaFold DB A0A1V2R9J2

References