Detailed information of TA system
Overview
TA module
| Type | IV | Classification (family/domain) | sdenTA/AbiEii(toxin) |
| Location | 4275154..4276594 | Replicon | chromosome |
| Accession | NZ_CP065177 | ||
| Organism | Pectobacterium quasiaquaticum strain A477-S1-J17 | ||
Toxin (Protein)
| Gene name | sdenT | Uniprot ID | - |
| Locus tag | IG609_RS19570 | Protein ID | WP_193399053.1 |
| Coordinates | 4275154..4276041 (-) | Length | 296 a.a. |
Antitoxin (Protein)
| Gene name | sdenA | Uniprot ID | - |
| Locus tag | IG609_RS19575 | Protein ID | WP_193399052.1 |
| Coordinates | 4276070..4276594 (-) | Length | 175 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| IG609_RS19545 (IG609_019525) | 4270670..4271578 | + | 909 | WP_193400275.1 | LysR family transcriptional regulator | - |
| IG609_RS19550 (IG609_019530) | 4271677..4272540 | + | 864 | WP_102117032.1 | YicC/YloC family endoribonuclease | - |
| IG609_RS19555 (IG609_019535) | 4272795..4273049 | - | 255 | Protein_3813 | IS1-like element transposase | - |
| IG609_RS19560 (IG609_019540) | 4273102..4274457 | - | 1356 | WP_193399054.1 | type II toxin-antitoxin system HipA family toxin | - |
| IG609_RS19565 (IG609_019545) | 4274447..4274737 | - | 291 | WP_180785889.1 | helix-turn-helix transcriptional regulator | - |
| IG609_RS19570 (IG609_019550) | 4275154..4276041 | - | 888 | WP_193399053.1 | nucleotidyl transferase AbiEii/AbiGii toxin family protein | Toxin |
| IG609_RS19575 (IG609_019555) | 4276070..4276594 | - | 525 | WP_193399052.1 | hypothetical protein | Antitoxin |
| IG609_RS19580 (IG609_019560) | 4276739..4277491 | - | 753 | WP_226373219.1 | hypothetical protein | - |
| IG609_RS19585 (IG609_019565) | 4277743..4278762 | - | 1020 | WP_193399051.1 | SEC-C domain-containing protein | - |
| IG609_RS19590 (IG609_019570) | 4278884..4279177 | - | 294 | WP_193400968.1 | helix-turn-helix transcriptional regulator | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Genomic island | - | - | 4273102..4285202 | 12100 | |
| - | flank | IS/Tn | - | - | 4272747..4273049 | 302 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 296 a.a. Molecular weight: 34231.20 Da Isoelectric Point: 6.1730
>T182261 WP_193399053.1 NZ_CP065177:c4276041-4275154 [Pectobacterium quasiaquaticum]
MLKQQIRQIVQSNPDYAAVTPVIEKEILHHDIIDVLIKQGVMQRLTFIGGTSLRMCYNSSRLSEDLDFNGGHDFKPSAFE
GLESEIQTYIQNKYETEVWVNKPSGEQQGDTVSWKISIVKEANRPDLPRQKMHIDVCAIPSFDIEKRPLINHYDIVVPTE
GILVPVQSLQETLADKLIALAYRARRIKPRDIWDIVWIKQRGIDLSKTLVEKKLTARHKQTDDFRQALSIQLAKLMSQDE
VRDDFNMEMSRFIPKQIKERTLDNPEYWDYVQREVHAITSELLNDVTPKNPFDMG
MLKQQIRQIVQSNPDYAAVTPVIEKEILHHDIIDVLIKQGVMQRLTFIGGTSLRMCYNSSRLSEDLDFNGGHDFKPSAFE
GLESEIQTYIQNKYETEVWVNKPSGEQQGDTVSWKISIVKEANRPDLPRQKMHIDVCAIPSFDIEKRPLINHYDIVVPTE
GILVPVQSLQETLADKLIALAYRARRIKPRDIWDIVWIKQRGIDLSKTLVEKKLTARHKQTDDFRQALSIQLAKLMSQDE
VRDDFNMEMSRFIPKQIKERTLDNPEYWDYVQREVHAITSELLNDVTPKNPFDMG
Download Length: 888 bp
>T182261 NZ_CP086370:c452143-451649 [Massilia sp. HC52]
ATGAGTTTGCGGCTCACCCCGCCCGTGCCGCTCGCGGCCACCCACCTTTTGGATGGATTCGAGTGCGGCGAAGCAGCACT
AGACGGGTGGCTCAAGCGACGCGCAATGGCCAACCAAGTGAGCAATGCCAGCCGCACATTTGTCGTAGCGGATCAGGATG
GCCATGTCTATGGCTACTATGCCATGGCCGCGGGCGCAGTCGCTCACCAAATGGCAACCGGCTCGGTCCGCCGGAACATG
CCGGACCCCGTCCCAGTATTGGTCCTGGCGCGGCTAGCGGTTGATCGCCGTGCCCAAGGCATGAAGATTGGTGCCGCCCT
ACTGCAGGACGCTGTCAACAGGGCGGTGACGGTTTCCCGGCATGCCGGCGTCCGAGCCCTGCTGGTACATGCGCTTAACG
ACACCGCCAAGAAGTTCTACGAACACTATGGCTTCCAGGAGTCGCCGCAACATCCGATGACGCTGATGTTACGCTTGAAT
GCCGTCAAGGAATGA
ATGAGTTTGCGGCTCACCCCGCCCGTGCCGCTCGCGGCCACCCACCTTTTGGATGGATTCGAGTGCGGCGAAGCAGCACT
AGACGGGTGGCTCAAGCGACGCGCAATGGCCAACCAAGTGAGCAATGCCAGCCGCACATTTGTCGTAGCGGATCAGGATG
GCCATGTCTATGGCTACTATGCCATGGCCGCGGGCGCAGTCGCTCACCAAATGGCAACCGGCTCGGTCCGCCGGAACATG
CCGGACCCCGTCCCAGTATTGGTCCTGGCGCGGCTAGCGGTTGATCGCCGTGCCCAAGGCATGAAGATTGGTGCCGCCCT
ACTGCAGGACGCTGTCAACAGGGCGGTGACGGTTTCCCGGCATGCCGGCGTCCGAGCCCTGCTGGTACATGCGCTTAACG
ACACCGCCAAGAAGTTCTACGAACACTATGGCTTCCAGGAGTCGCCGCAACATCCGATGACGCTGATGTTACGCTTGAAT
GCCGTCAAGGAATGA
Antitoxin
Download Length: 175 a.a. Molecular weight: 19460.53 Da Isoelectric Point: 9.0551
>AT182261 WP_193399052.1 NZ_CP065177:c4276594-4276070 [Pectobacterium quasiaquaticum]
MTKSDELLNVFSKAVNAGGGIHSATELAFMQGVPCDSAFRKFLADCVKRGLLRRVVKGFYESVITPPEPETAIYKIIKKL
RSGVLNYISLESQLSHTGDISQVVMGRVTVVTKGRSGCFDTPYGVIEFTHTKKPVEQVAPNLYYDPDIKMYRAYKEQAIA
DLKHCQRNLHMLES
MTKSDELLNVFSKAVNAGGGIHSATELAFMQGVPCDSAFRKFLADCVKRGLLRRVVKGFYESVITPPEPETAIYKIIKKL
RSGVLNYISLESQLSHTGDISQVVMGRVTVVTKGRSGCFDTPYGVIEFTHTKKPVEQVAPNLYYDPDIKMYRAYKEQAIA
DLKHCQRNLHMLES
Download Length: 525 bp
>AT182261 NZ_CP086370:c452412-452140 [Massilia sp. HC52]
ATGCGTGACGCCGCCATCAATTTGCGGGCTTTGCCCGAGCAGCGGGACTTGATTGATCGCGCCGCAAACCTGTTGGGCAA
GAACCGTTCGGATTTTATGCTTGAAGCCGCCTGTGAAAAAGCCCAGGAGGTCGTACTCGATCAGGTTTTTTTCAGCATGG
ATACAGACAAATTCAAGCACTTCAATGCCCTCCTCGATGCACCGCCTAGCCACAATCCCGGACTTGAACGACTAATGGCC
GTTGCCGCTCCTTGGATTACTGCCAAGAAATGA
ATGCGTGACGCCGCCATCAATTTGCGGGCTTTGCCCGAGCAGCGGGACTTGATTGATCGCGCCGCAAACCTGTTGGGCAA
GAACCGTTCGGATTTTATGCTTGAAGCCGCCTGTGAAAAAGCCCAGGAGGTCGTACTCGATCAGGTTTTTTTCAGCATGG
ATACAGACAAATTCAAGCACTTCAATGCCCTCCTCGATGCACCGCCTAGCCACAATCCCGGACTTGAACGACTAATGGCC
GTTGCCGCTCCTTGGATTACTGCCAAGAAATGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|