Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | vagCD/VapC-VagC |
Location | 3606090..3606730 | Replicon | chromosome |
Accession | NZ_CP065177 | ||
Organism | Pectobacterium quasiaquaticum strain A477-S1-J17 |
Toxin (Protein)
Gene name | vagD | Uniprot ID | A0A7V8Q162 |
Locus tag | IG609_RS16530 | Protein ID | WP_039278477.1 |
Coordinates | 3606090..3606506 (-) | Length | 139 a.a. |
Antitoxin (Protein)
Gene name | vagC | Uniprot ID | A0A086EF97 |
Locus tag | IG609_RS16535 | Protein ID | WP_039278475.1 |
Coordinates | 3606503..3606730 (-) | Length | 76 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
IG609_RS16505 (IG609_016490) | 3601471..3601635 | - | 165 | WP_193398323.1 | hypothetical protein | - |
IG609_RS16510 (IG609_016495) | 3601678..3602661 | - | 984 | WP_193398322.1 | quinone oxidoreductase | - |
IG609_RS16515 (IG609_016500) | 3602789..3604195 | + | 1407 | WP_039490832.1 | replicative DNA helicase | - |
IG609_RS16520 (IG609_016505) | 3604237..3605319 | + | 1083 | WP_193398321.1 | alanine racemase | - |
IG609_RS16525 (IG609_016510) | 3605312..3605950 | + | 639 | WP_193398320.1 | hypothetical protein | - |
IG609_RS16530 (IG609_016515) | 3606090..3606506 | - | 417 | WP_039278477.1 | type II toxin-antitoxin system VapC family toxin | Toxin |
IG609_RS16535 (IG609_016520) | 3606503..3606730 | - | 228 | WP_039278475.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin |
IG609_RS16540 (IG609_016525) | 3607344..3607823 | + | 480 | WP_193398319.1 | Lrp/AsnC family transcriptional regulator | - |
IG609_RS16545 (IG609_016530) | 3608074..3608688 | + | 615 | WP_010279239.1 | YitT family protein | - |
IG609_RS16550 (IG609_016535) | 3608752..3609945 | + | 1194 | WP_193398318.1 | amino acid aminotransferase | - |
IG609_RS16555 (IG609_016540) | 3610029..3610526 | + | 498 | WP_193398317.1 | M48 family metallopeptidase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 139 a.a. Molecular weight: 15274.80 Da Isoelectric Point: 8.2931
>T182259 WP_039278477.1 NZ_CP065177:c3606506-3606090 [Pectobacterium quasiaquaticum]
VSRLFMLDTNICSFIMREHPAEVIEKLQQCTLRRDRIVVSAITYAEMRFGAVGKKASPRHMQLVDAFCRRLDAVLPWDSA
AVDATTKIKIELAAAGTPIGPNDTAIAGHAISAKAILVTNNLREFERVPGLTLEDWVK
VSRLFMLDTNICSFIMREHPAEVIEKLQQCTLRRDRIVVSAITYAEMRFGAVGKKASPRHMQLVDAFCRRLDAVLPWDSA
AVDATTKIKIELAAAGTPIGPNDTAIAGHAISAKAILVTNNLREFERVPGLTLEDWVK
Download Length: 417 bp
>T182259 NZ_CP086369:4253003-4253281 [Pectobacterium versatile]
ATGAAAAAGCAAAGGGAAATTGCATATTCTGGTCAATTCCAACGTGATGTGAAAAAAGCTCAACGGCGACATAAAAACAT
GAACAAGCTTAAAACGCTTATGCAGCTTTTGCTTGAAGACAAACGACCGTTGCCACAGGAATATCAGGATCACCCCCTCC
AGGGAAACTATAAGGGCTACAGAGATGCGCATATCGAGCCGGATTGGCTTCTTATTTACAAGCTGACCGATGACGTTTTG
CGTTTTGAACGTACAGGGACGCACGCTGACCTTTTCTAA
ATGAAAAAGCAAAGGGAAATTGCATATTCTGGTCAATTCCAACGTGATGTGAAAAAAGCTCAACGGCGACATAAAAACAT
GAACAAGCTTAAAACGCTTATGCAGCTTTTGCTTGAAGACAAACGACCGTTGCCACAGGAATATCAGGATCACCCCCTCC
AGGGAAACTATAAGGGCTACAGAGATGCGCATATCGAGCCGGATTGGCTTCTTATTTACAAGCTGACCGATGACGTTTTG
CGTTTTGAACGTACAGGGACGCACGCTGACCTTTTCTAA
Antitoxin
Download Length: 76 a.a. Molecular weight: 8879.08 Da Isoelectric Point: 4.8359
>AT182259 WP_039278475.1 NZ_CP065177:c3606730-3606503 [Pectobacterium quasiaquaticum]
MRIVSVFKNGNNRAIRLPRDMDFEGVNELEIVREGDTIMLRPVKPNWHSFLQEDRADADFMTERQDVVEEGRFKL
MRIVSVFKNGNNRAIRLPRDMDFEGVNELEIVREGDTIMLRPVKPNWHSFLQEDRADADFMTERQDVVEEGRFKL
Download Length: 228 bp
>AT182259 NZ_CP086369:4252739-4252999 [Pectobacterium versatile]
ATGGCAGCGAATGCATTTGTACGTGCCCGTATTGATGAGAATCTTAAAAATGAAGCAGCGGAAGTGTTGGCTAGCATGGG
GTTGACGGTATCGGATCTGGTGCGCATAACGTTAACGAAAGTGGCTAAAGAAAAAGCACTTCCATTTGATATGCATGTCC
CTAATAAGCTTACCGCACAAACGATGGCTGACAGCGAGAAAGGTGTTGATGTCTATACAGCAAAAGACGCCGCCGATCTG
TTTGATAAATTAGGGATCTAA
ATGGCAGCGAATGCATTTGTACGTGCCCGTATTGATGAGAATCTTAAAAATGAAGCAGCGGAAGTGTTGGCTAGCATGGG
GTTGACGGTATCGGATCTGGTGCGCATAACGTTAACGAAAGTGGCTAAAGAAAAAGCACTTCCATTTGATATGCATGTCC
CTAATAAGCTTACCGCACAAACGATGGCTGACAGCGAGAAAGGTGTTGATGTCTATACAGCAAAAGACGCCGCCGATCTG
TTTGATAAATTAGGGATCTAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A7V8Q162 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A086EF97 |