Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type VII Classification (family/domain) HepT-MntA/HepT(toxin)
Location 2986259..2987058 Replicon chromosome
Accession NZ_CP065177
Organism Pectobacterium quasiaquaticum strain A477-S1-J17

Toxin (Protein)


Gene name hepT Uniprot ID -
Locus tag IG609_RS13690 Protein ID WP_193400948.1
Coordinates 2986639..2987058 (+) Length 140 a.a.

Antitoxin (Protein)


Gene name mntA Uniprot ID -
Locus tag IG609_RS13685 Protein ID WP_193400946.1
Coordinates 2986259..2986642 (+) Length 128 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IG609_RS13670 (IG609_013665) 2981459..2982595 - 1137 WP_193400941.1 polysaccharide export protein -
IG609_RS13675 (IG609_013670) 2982713..2983810 - 1098 WP_193400942.1 UDP-N-acetylglucosamine--undecaprenyl-phosphate N-acetylglucosaminephosphotransferase -
IG609_RS13680 (IG609_013675) 2984537..2986123 + 1587 WP_193400944.1 TerC family protein -
IG609_RS13685 (IG609_013680) 2986259..2986642 + 384 WP_193400946.1 nucleotidyltransferase domain-containing protein Antitoxin
IG609_RS13690 (IG609_013685) 2986639..2987058 + 420 WP_193400948.1 DUF86 domain-containing protein Toxin
IG609_RS13695 (IG609_013690) 2987110..2988462 - 1353 WP_193400950.1 anaerobic C4-dicarboxylate transporter DcuC -
IG609_RS13700 (IG609_013695) 2988724..2990559 - 1836 WP_193400952.1 outer membrane assembly protein AsmA -
IG609_RS13705 (IG609_013700) 2990623..2991204 - 582 WP_102116608.1 dCTP deaminase -
IG609_RS13710 (IG609_013705) 2991311..2991952 - 642 WP_010281304.1 uridine kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease HepT-like

(13-130)

Antitoxin

Polymerase beta, nucleotidyltransferase

(5-91)


Sequences

Toxin        


Download         Length: 140 a.a.        Molecular weight: 16116.41 Da        Isoelectric Point: 6.4799

>T182253 WP_193400948.1 NZ_CP065177:2986639-2987058 [Pectobacterium quasiaquaticum]
MTDILLNKSSTIQRCLRRIREEFDTEEGFRQNFTKQDSVILNIQRACEAAIDIANYLIRIKQLGIPQSSRDSFALLAANQ
IITLELSDNLQEMVGLRNIAVHDYQTLNLDIVIHVISHRLSDFERFIKQIARYSDSQHL

Download         Length: 420 bp

>T182253 NZ_CP086369:c3497757-3497473 [Pectobacterium versatile]
ATGAGTTATAAGCTGGAGTTTGAAGAGCACGCGCTGAAAGAATTTAAGAAGCTGGGTGCGCCCGTACGGGAGCAGTTCAC
CAAAAAACTGAAAGAGGTTTTACAACATCCCCACGTTCCCGCCAACCGACTTCATGGAATGGCTGACTGCTACAAAATCA
AACTTCGTTCCGCTGGCTATCGGCTAGTGTATCAAGTGCTTGAACATGAGATCGTGGTGCTGGTTTTAGCTGTGGGCAAA
CGGGAACGCTCAGAAGTTTATAAAACAGCGAAAGACCGACTATAA

Antitoxin


Download         Length: 128 a.a.        Molecular weight: 14365.63 Da        Isoelectric Point: 5.1964

>AT182253 WP_193400946.1 NZ_CP065177:2986259-2986642 [Pectobacterium quasiaquaticum]
MFDEIVLTLKKQMPDIKIIYLFGSQATGNARADSDVDIAIMATRALGPVERWELSHQLAKKIGHDVDLIDLLQASTVLKM
EIVRNGKLLYDVEATAGEFEMTTLSMYQHLQKERADIIRSFNQDLKA

Download         Length: 384 bp

>AT182253 NZ_CP086369:c3497998-3497747 [Pectobacterium versatile]
ATGTCCGTACAACCTATCCTTGCGAATGCTGCCGTAAGTATCAGCGACTTTAAAAAATCGCCCAATGCCGCGCTTAAGGA
AGCTAACGGCGAGCCTGTAGCTGTGCTCACCAATGGCCGTATCTCTGGCTATTATGTTTCTCCGGAAACATGGGAAGCGT
TGGCCGATTATCAGGAAGATATCGAACTTGCCAAAATCGCCCGTTCCCGGATGAAGGGGAAGCGTGTGAAGGTCGATCTG
GATGAGTTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References