Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 1583085..1583719 Replicon chromosome
Accession NZ_CP065177
Organism Pectobacterium quasiaquaticum strain A477-S1-J17

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag IG609_RS07325 Protein ID WP_193399495.1
Coordinates 1583315..1583719 (+) Length 135 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag IG609_RS07320 Protein ID WP_104209861.1
Coordinates 1583085..1583315 (+) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IG609_RS07285 (IG609_007290) 1579133..1579291 + 159 WP_189654467.1 hypothetical protein -
IG609_RS07290 (IG609_007295) 1579438..1580271 + 834 WP_193399489.1 hypothetical protein -
IG609_RS07295 (IG609_007300) 1580329..1580679 + 351 WP_193399490.1 hypothetical protein -
IG609_RS07300 (IG609_007305) 1580802..1581275 + 474 WP_193399491.1 DNA repair protein RadC -
IG609_RS07305 (IG609_007310) 1581315..1581650 + 336 WP_193399492.1 type IV toxin-antitoxin system YeeU family antitoxin -
IG609_RS07310 (IG609_007315) 1581720..1582040 + 321 WP_193399493.1 TA system toxin CbtA family protein -
IG609_RS07315 (IG609_007320) 1582158..1582991 + 834 WP_193399494.1 DUF4942 domain-containing protein -
IG609_RS07320 (IG609_007325) 1583085..1583315 + 231 WP_104209861.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
IG609_RS07325 (IG609_007330) 1583315..1583719 + 405 WP_193399495.1 tRNA(fMet)-specific endonuclease VapC Toxin
IG609_RS07330 (IG609_007335) 1584121..1584333 - 213 Protein_1405 IS110 family transposase -
IG609_RS07335 (IG609_007340) 1584422..1584685 + 264 Protein_1406 integrase core domain-containing protein -
IG609_RS07340 (IG609_007345) 1584715..1584933 + 219 Protein_1407 IS3 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-124)

Antitoxin

SpoVT-AbrB domain

(7-54)


Sequences

Toxin        


Download         Length: 135 a.a.        Molecular weight: 15031.27 Da        Isoelectric Point: 8.0239

>T182251 WP_193399495.1 NZ_CP065177:1583315-1583719 [Pectobacterium quasiaquaticum]
MLKYLLDTNICIYTIKNKPQEVKEAFYRHYGQFAISSITLMELIYGAEKSVNPEKNLAVIEGFSARLEVQTYGFDAAVHT
GQIRAELARQGTPIGPYDAMLAGHARSAGLILVTNNVREFERVPGLRVENWVGR

Download         Length: 405 bp

>T182251 NZ_CP086369:c3233252-3232323 [Pectobacterium versatile]
ATGGATCAGCGTGATATTTATGCCCGGCAGGTCAAACTGTTAATGACCACCCTGCCGTATGTGGCGAAAGAACCCTGTTT
CGCGCTGAAAGGCGGCACAGCAATTAATTTATTTGTGCAGGATTTTCCTCGTCTATCGGTAGATATCGATCTGGTTTATC
AAACCTTCATAGATCGTGATACCGATCTAATCGCTATTGACGATGCATTGATGCGTATTACGGAATCGCTGAACGGCAGG
CCGGGGATCACGGCGATCCGGCAGGAGAATAAAGCCGATGAAAAACGCATCATCGTTAACACCGTTGATGCGCAGATAAA
GATTGAAGTCAGCCCAGTTTGGCGTGGATTGCTGTTGCCTCCAGCAGAAATGCCAGTATGCGAGCAGGTGGAAATGGAAT
TCGGCTTTACCACTATGAATGTCGTTTCACTGGCAGATCTTTACGGCGGTAAAATCTGCGCTGCGCTCGATCGCCAGCAT
CCACGCGATCTGTTTGACGTGCTAAATATGCTGGAGAAACCGGGCCTCACACGTGAACTCTTTGATGGCTTTCTTTGCTA
TCTGGCTGGTCATCCCCGTCCCATCACCGAACTACTGGCACCAAACTGGGACATTGCACGTATCACCACACTGTACCAAC
AAGAATTTTCGGGCATGACGCAACAGGCAACGTCGCTGGAATCGCTTTTGTCAGTGACGATTTTACTGCCGCAAGCATTG
AGATCTCACTTTACTGCTCAGGATAAACAGTTTTTACTGAGCTATAAGCAAAACACCCCTGACTGGTCGCTATATCGCTA
TCCTGATATTCAACATCTTCCCGCTATTCGTTGGAAACAGCATAATTTAGCGGCCTTACATGCTAAAAATCCGGCCAAAT
TTAGTGCGGCGGTAAGCAAGCTTGAGAAGGTTCTGGAACAGCGATTTTAG

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8666.74 Da        Isoelectric Point: 4.4230

>AT182251 WP_104209861.1 NZ_CP065177:1583085-1583315 [Pectobacterium quasiaquaticum]
MEKTTVFKSNRSQAVRLPKAVALPDDVKQVDIVAIGRTRIITPAGESWDSWFEGESVTPDFMITREQPDEQVREDF

Download         Length: 231 bp

>AT182251 NZ_CP086369:c3234021-3233239 [Pectobacterium versatile]
TTGACTAATTATCTAAACTGGCTAATGCAAAACACGCTGCCCGGTCAGGTGTTGCTCCAATCATGGCTTACCCGCAACGG
CATAGATCGTAAGCTCTCTTACGTCTATGTCCAAAACGGTTGGCTTAGGCGAATCGCGCACGGCGTTTACTGCCGGACGG
GCCGAGAACCGGATTGGGTAGATGCGGTTTATTGCCTGCAAACACAATGGGAAAAACCAATACGGGTAGCAGGACTGACG
AGCATCGCGTTACAAGGTTATTCCCACTATACCGAACTGGGTAAACCTCAAATTTGGCTCACGATCCCGGCGTACATTAC
GCTACCGGGGTGGTTCGCTGCCTTTGAAAAATCCGCCACCTTTGTCGTGCTCTATACATCAGACCTGTCGGTTGATGTGA
TGCCATTCACGACAGAACTGAGAATCGGCGATCGGCGGCTGACTGGCAGTGTTCCAGAACTTGCCGCATATGAAATCGCC
AGCGGTGTTCCCACACAAATATCATTTGAGCATGCTGATGCATTGTTTCAGGGTCTACACCTTCTCAGTCCGCGTAAATT
ACAGGCACTGCTCTGCGCCAGTCATTCAGTAAAAACCAACAGGGTGATGCTCTACCTTGCCCAGCGTAATGGGCATCCTT
ATTTTCAGTATCTCGATAAAAGTGGTATAGAAGTAGGCGCAGGAAAGCGGCAAATTGTCCCCGGCGGCTGGCTGGAACCG
GATTACCAGATCACTGTTCCTAGGGAGTTTAAATCGGAAGGAGTCGAAGATGGATCAGCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References