Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1929544..1929689 Replicon chromosome
Accession NZ_CP065172
Organism Klebsiella pneumoniae strain KPN110

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1929580..1929682 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1929544..1929689 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I3U25_RS09420 1924674..1926734 + 2061 WP_004151449.1 oligopeptidase B -
I3U25_RS09425 1926738..1927397 - 660 WP_002911407.1 exodeoxyribonuclease X -
I3U25_RS09430 1927476..1927706 - 231 WP_040147502.1 DNA polymerase III subunit theta -
I3U25_RS09435 1927819..1928193 + 375 WP_004151448.1 CopC domain-containing protein YobA -
I3U25_RS09440 1928197..1929066 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
I3U25_RS09445 1929083..1929421 + 339 WP_002911404.1 YebY family protein -
- 1929544..1929689 - 146 - - Antitoxin
- 1929580..1929682 + 103 - - Toxin
I3U25_RS09450 1930057..1930200 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
I3U25_RS09455 1930305..1931273 - 969 WP_004151446.1 VirK/YbjX family protein -
I3U25_RS09460 1931430..1932083 + 654 WP_032415192.1 protein-serine/threonine phosphatase -
I3U25_RS09465 1932080..1932271 - 192 WP_002911395.1 YebW family protein -
I3U25_RS09470 1932369..1932608 - 240 WP_002911393.1 YebV family protein -
I3U25_RS09475 1932724..1934157 - 1434 WP_032415191.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T182226 NZ_CP065172:1929580-1929682 [Klebsiella pneumoniae]
GCAAGGCGGCTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT182226 NZ_CP065172:c1929689-1929544 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGCCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References