Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1935274..1935419 Replicon chromosome
Accession NZ_CP065167
Organism Klebsiella pneumoniae strain KPN114

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1935310..1935412 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1935274..1935419 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I3U24_RS09455 1930404..1932464 + 2061 WP_004151449.1 oligopeptidase B -
I3U24_RS09460 1932468..1933127 - 660 WP_002911407.1 exodeoxyribonuclease X -
I3U24_RS09465 1933206..1933436 - 231 WP_002911406.1 DNA polymerase III subunit theta -
I3U24_RS09470 1933549..1933923 + 375 WP_004151448.1 CopC domain-containing protein YobA -
I3U24_RS09475 1933927..1934796 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
I3U24_RS09480 1934813..1935151 + 339 WP_002911404.1 YebY family protein -
- 1935274..1935419 - 146 - - Antitoxin
- 1935310..1935412 + 103 - - Toxin
I3U24_RS09485 1935787..1935930 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
I3U24_RS09490 1936035..1937003 - 969 WP_014907334.1 VirK/YbjX family protein -
I3U24_RS09495 1937160..1937813 + 654 WP_009484457.1 protein-serine/threonine phosphatase -
I3U24_RS09500 1937810..1938001 - 192 WP_002911395.1 YebW family protein -
I3U24_RS09505 1938099..1938338 - 240 WP_002911393.1 YebV family protein -
I3U24_RS09510 1938454..1939887 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T182208 NZ_CP065167:1935310-1935412 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT182208 NZ_CP065167:c1935419-1935274 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References