Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2013638..2013782 | Replicon | chromosome |
| Accession | NZ_CP065162 | ||
| Organism | Klebsiella variicola strain KPN029 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2013674..2013776 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2013638..2013782 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| I3U23_RS10015 | 2008767..2010827 | + | 2061 | WP_008804266.1 | oligopeptidase B | - |
| I3U23_RS10020 | 2010831..2011490 | - | 660 | WP_008804267.1 | exodeoxyribonuclease X | - |
| I3U23_RS10025 | 2011569..2011799 | - | 231 | WP_012541260.1 | DNA polymerase III subunit theta | - |
| I3U23_RS10030 | 2011913..2012287 | + | 375 | WP_023340401.1 | CopC domain-containing protein YobA | - |
| I3U23_RS10035 | 2012291..2013160 | + | 870 | WP_012541262.1 | copper homeostasis membrane protein CopD | - |
| I3U23_RS10040 | 2013177..2013515 | + | 339 | WP_008804271.1 | YebY family protein | - |
| - | 2013638..2013782 | - | 145 | - | - | Antitoxin |
| - | 2013674..2013776 | + | 103 | - | - | Toxin |
| I3U23_RS10045 | 2014161..2014304 | - | 144 | WP_048268691.1 | Ecr family regulatory small membrane protein | - |
| I3U23_RS10050 | 2014408..2015376 | - | 969 | WP_162493241.1 | VirK/YbjX family protein | - |
| I3U23_RS10055 | 2015533..2016186 | + | 654 | WP_022066249.1 | protein-serine/threonine phosphatase | - |
| I3U23_RS10060 | 2016183..2016374 | - | 192 | WP_002911395.1 | YebW family protein | - |
| I3U23_RS10065 | 2016472..2016711 | - | 240 | WP_002911393.1 | YebV family protein | - |
| I3U23_RS10070 | 2016827..2018260 | - | 1434 | WP_012967754.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 1926097..2031200 | 105103 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T182188 NZ_CP065162:2013674-2013776 [Klebsiella variicola]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 145 bp
>AT182188 NZ_CP065162:c2013782-2013638 [Klebsiella variicola]
ACCGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
ACCGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT