Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2013638..2013782 Replicon chromosome
Accession NZ_CP065162
Organism Klebsiella variicola strain KPN029

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2013674..2013776 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2013638..2013782 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I3U23_RS10015 2008767..2010827 + 2061 WP_008804266.1 oligopeptidase B -
I3U23_RS10020 2010831..2011490 - 660 WP_008804267.1 exodeoxyribonuclease X -
I3U23_RS10025 2011569..2011799 - 231 WP_012541260.1 DNA polymerase III subunit theta -
I3U23_RS10030 2011913..2012287 + 375 WP_023340401.1 CopC domain-containing protein YobA -
I3U23_RS10035 2012291..2013160 + 870 WP_012541262.1 copper homeostasis membrane protein CopD -
I3U23_RS10040 2013177..2013515 + 339 WP_008804271.1 YebY family protein -
- 2013638..2013782 - 145 - - Antitoxin
- 2013674..2013776 + 103 - - Toxin
I3U23_RS10045 2014161..2014304 - 144 WP_048268691.1 Ecr family regulatory small membrane protein -
I3U23_RS10050 2014408..2015376 - 969 WP_162493241.1 VirK/YbjX family protein -
I3U23_RS10055 2015533..2016186 + 654 WP_022066249.1 protein-serine/threonine phosphatase -
I3U23_RS10060 2016183..2016374 - 192 WP_002911395.1 YebW family protein -
I3U23_RS10065 2016472..2016711 - 240 WP_002911393.1 YebV family protein -
I3U23_RS10070 2016827..2018260 - 1434 WP_012967754.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1926097..2031200 105103


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T182188 NZ_CP065162:2013674-2013776 [Klebsiella variicola]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 145 bp

>AT182188 NZ_CP065162:c2013782-2013638 [Klebsiella variicola]
ACCGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References