Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4108948..4109216 Replicon chromosome
Accession NZ_CP065152
Organism Escherichia coli O150:H6 strain FEX669

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4108986..4109088 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4108948..4109216 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H7994_RS19860 4106105..4107544 + 1440 WP_012601553.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
H7994_RS19865 4107662..4107880 + 219 WP_096939647.1 DUF1480 family protein -
H7994_RS19870 4108003..4108194 + 192 WP_001317886.1 YebW family protein -
H7994_RS19875 4108195..4108851 - 657 WP_000812743.1 protein-serine/threonine phosphatase -
- 4108948..4109216 + 269 - - Antitoxin
- 4108986..4109088 - 103 - - Toxin
H7994_RS19880 4109246..4109587 - 342 WP_196316002.1 YebY family protein -
H7994_RS19885 4109600..4110472 - 873 WP_000879311.1 copper homeostasis membrane protein CopD -
H7994_RS19890 4110476..4110850 - 375 WP_000168747.1 CopC domain-containing protein YobA -
H7994_RS19895 4110989..4111219 + 231 WP_000916763.1 DNA polymerase III subunit theta -
H7994_RS19900 4111321..4111977 + 657 WP_000011664.1 carbon-nitrogen hydrolase family protein -
H7994_RS19905 4112000..4112662 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T182156 NZ_CP065152:c4109088-4108986 [Escherichia coli O150:H6]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT182156 NZ_CP065152:4108948-4109216 [Escherichia coli O150:H6]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References