Detailed information of TA system TA182136

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/YafN(antitoxin)
• Location: 1500084..1500649
• Replicon: chromosome
• Accession: NZ_CP065151
• Organism: Vibrio kanaloae strain R17

Toxin (Protein)

• Gene name: relE
• Uniprot ID: A0A4U1W7G7
• Locus tag: BTD91_RS20845
• Protein ID: WP_053815743.1
• Coordinates: 1500084..1500371 (-)
• Length: 96 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: BTD91_RS20850
• Protein ID: WP_077681057.1
• Coordinates: 1500368..1500649 (-)
• Length: 94 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BTD91_RS20830	1496815..1497234	-	420	WP_046224149.1	DUF1311 domain-containing protein	-
BTD91_RS20835	1497781..1497873	-	93	WP_077681855.1	DUF3265 domain-containing protein	-
BTD91_RS20840	1498408..1498881	-	474	WP_077681856.1	GNAT family N-acetyltransferase	-
BTD91_RS20845	1500084..1500371	-	288	WP_053815743.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
BTD91_RS20850	1500368..1500649	-	282	WP_077681057.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
BTD91_RS20855	1500850..1501344	-	495	WP_077681056.1	GNAT family N-acetyltransferase	-
BTD91_RS20860	1502044..1502598	-	555	WP_077681054.1	hypothetical protein	-
BTD91_RS20865	1502745..1503515	-	771	WP_025623994.1	hypothetical protein	-
BTD91_RS20870	1504160..1504948	-	789	WP_077681053.1	DUF2971 domain-containing protein	-
BTD91_RS20875	1504979..1505071	-	93	WP_077681052.1	DUF3265 domain-containing protein	-
BTD91_RS20880	1505096..1505302	-	207	WP_077681051.1	KTSC domain-containing protein	-
BTD91_RS20885	1505312..1505530	-	219	WP_025543067.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	1482988..1505530	22542
	-	inside	Integron	-	katA	1346..1507736	1506390

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (3-88)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (9-74)

Sequences

Toxin

Protein

• Length: 96 a.a.
• Molecular weight: 10961.60 Da
• Isoelectric Point: 5.0872

>T182136 WP_053815743.1 NZ_CP065151:c1500371-1500084 [Vibrio kanaloae]
MKVVWSPLALQKLGDAAEFISLDNPVAAENWVNEVFDKTELLSSMPEMGRTVPELPHTNYREILFGHYRIIYSLSHEIRV
LTVRNCRQMLTESDV

Nucleotide

• Length: 288 bp

>T182136 NZ_CP086334:c2878096-2877923 [Escherichia coli]
ATGGCACTATTCTCTAAAATATTAATTTTTTATGTGATTGGTGTGAACATATCCTTTGTCATTATCTGGTTTATCTCACA
TGAGAAAACACATATTCGTTTACTTAGTGCATTCCTGGTCGGAATAACCTGGCCAATGAGTCTGCCTGTGGCATTACTTT
TTTCTCTCTTTTAG

Antitoxin

Protein

• Length: 94 a.a.
• Molecular weight: 10440.99 Da
• Isoelectric Point: 5.8719

>AT182136 WP_077681057.1 NZ_CP065151:c1500649-1500368 [Vibrio kanaloae]
MSRIHFDQDIQPLSEFRAGVTSFIKQINETRRPLVITQRGKGVAVVLDVAEYEAMQEKIELLEEMRTAEAQLASGLGISN
EDARAQVLGRIKK

Nucleotide

• Length: 282 bp

>AT182136 NZ_CP086334:c2878420-2878124 [Escherichia coli]
ATGGAAGGTAAAAACAAGTTCAATACTTATGTTGTTTCTTTTGATTATCCATCATCTTATTCCTCAGTGTTCTTAAGGTT
AAGATCATTGATGTATGATATGAATTTCTCCTCTATCGTGGCTGATGAATATGGGATACCACGACAATTGAATGAAAATT
CCTTCGCAATAACGACATCATTAGCCGCAAGTGAAATCGAAGATTTAATCAGGCTCAAATGCTTAGACTTACCGGATATT
GATTTTGACCTCAACATTATGACAGTTGATGACTATTTCCGTCAGTTTTACAAGTAG

Structures

Toxin

• AlphaFold DB: A0A4U1W7G7