Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relBE/RelE-RelB |
Location | 1484231..1484790 | Replicon | chromosome |
Accession | NZ_CP065151 | ||
Organism | Vibrio kanaloae strain R17 |
Toxin (Protein)
Gene name | relE | Uniprot ID | - |
Locus tag | BTD91_RS20740 | Protein ID | WP_077681805.1 |
Coordinates | 1484512..1484790 (+) | Length | 93 a.a. |
Antitoxin (Protein)
Gene name | relB | Uniprot ID | F9RXS2 |
Locus tag | BTD91_RS20735 | Protein ID | WP_006710667.1 |
Coordinates | 1484231..1484515 (+) | Length | 95 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
BTD91_RS20700 | 1479289..1479531 | - | 243 | WP_077681789.1 | helix-turn-helix domain-containing protein | - |
BTD91_RS20705 | 1479620..1480573 | - | 954 | WP_077681788.1 | hypothetical protein | - |
BTD91_RS20710 | 1480650..1481828 | - | 1179 | WP_077681787.1 | site-specific integrase | - |
BTD91_RS20715 | 1481995..1482111 | - | 117 | WP_077681793.1 | DUF3265 domain-containing protein | - |
BTD91_RS20720 | 1482102..1482851 | - | 750 | WP_077681864.1 | metallophosphatase family protein | - |
BTD91_RS20725 | 1482881..1482973 | - | 93 | WP_077681807.1 | DUF3265 domain-containing protein | - |
BTD91_RS20730 | 1482988..1484031 | - | 1044 | WP_077681806.1 | hypothetical protein | - |
BTD91_RS20735 | 1484231..1484515 | + | 285 | WP_006710667.1 | type II toxin-antitoxin system RelB/DinJ family antitoxin | Antitoxin |
BTD91_RS20740 | 1484512..1484790 | + | 279 | WP_077681805.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
BTD91_RS20745 | 1484927..1485700 | - | 774 | WP_077681804.1 | aminoglycoside phosphotransferase family protein | - |
BTD91_RS20750 | 1485837..1486259 | - | 423 | WP_077681803.1 | hypothetical protein | - |
BTD91_RS20755 | 1486406..1486993 | - | 588 | WP_077681802.1 | hypothetical protein | - |
BTD91_RS20760 | 1487098..1487775 | - | 678 | WP_077681800.1 | response regulator | - |
BTD91_RS20765 | 1487910..1488407 | - | 498 | WP_017057199.1 | hypothetical protein | - |
BTD91_RS20770 | 1488343..1488579 | - | 237 | WP_077681798.1 | DUF3265 domain-containing protein | - |
BTD91_RS20775 | 1488951..1489094 | - | 144 | WP_077681796.1 | DUF3265 domain-containing protein | - |
BTD91_RS20780 | 1489057..1489479 | - | 423 | WP_017054818.1 | GNAT family N-acetyltransferase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Genomic island | - | - | 1482988..1505530 | 22542 | |
- | inside | Integron | - | katA | 1346..1507736 | 1506390 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 93 a.a. Molecular weight: 10807.50 Da Isoelectric Point: 4.5370
>T182135 WP_077681805.1 NZ_CP065151:1484512-1484790 [Vibrio kanaloae]
MILWEEESLNDREKIFEFLYDFNPDAADKTDEIIEAKVENLLEQPLMGVQRDGIRGRLLIIPKISMIVSYWVDGSAIRVM
RVLHQKQKFPTD
MILWEEESLNDREKIFEFLYDFNPDAADKTDEIIEAKVENLLEQPLMGVQRDGIRGRLLIIPKISMIVSYWVDGSAIRVM
RVLHQKQKFPTD
Download Length: 279 bp
>T182135 NZ_CP086334:c2781430-2781080 [Escherichia coli]
ATGGTAAAGAAAAGTGAATTTGAACGGGGAGACATTGTGCTGGTTGGCTTTGATCCAGCAAGCGGCCATGAACAGCAAGG
TGCTGGTCGACCTGCGCTTGTGCTCTCCGTTCAAGCCTTTAATCAACTGGGAATGACGCTGGTGGCCCCCATTACGCAGG
GCGGAAATTTTGCCCGTTATGCCGGATTTAGCGTTCCTTTACATTGCGAAGAAGGCGATGTGCACGGCGTGGTGCTGGTG
AATCAGGTGCGGATGATGGATCTACGCGCCCGGCTGGCAAAGCGTATTGGTCTGGCTGCGGGTGAGGTGGTGGAAGAGGC
GTTATTACGTTTGCAGGCGGTGGTGGAATAA
ATGGTAAAGAAAAGTGAATTTGAACGGGGAGACATTGTGCTGGTTGGCTTTGATCCAGCAAGCGGCCATGAACAGCAAGG
TGCTGGTCGACCTGCGCTTGTGCTCTCCGTTCAAGCCTTTAATCAACTGGGAATGACGCTGGTGGCCCCCATTACGCAGG
GCGGAAATTTTGCCCGTTATGCCGGATTTAGCGTTCCTTTACATTGCGAAGAAGGCGATGTGCACGGCGTGGTGCTGGTG
AATCAGGTGCGGATGATGGATCTACGCGCCCGGCTGGCAAAGCGTATTGGTCTGGCTGCGGGTGAGGTGGTGGAAGAGGC
GTTATTACGTTTGCAGGCGGTGGTGGAATAA
Antitoxin
Download Length: 95 a.a. Molecular weight: 10857.17 Da Isoelectric Point: 8.0515
>AT182135 WP_006710667.1 NZ_CP065151:1484231-1484515 [Vibrio kanaloae]
MDTRIQFRVDDEIKRLAQQMAESQGRTLSDACRELTEQMAEQQRKALSHDAWLTEQVNLAFEKFDSGKASFVDHDSAKAR
MAERKAKIRSRGQQ
MDTRIQFRVDDEIKRLAQQMAESQGRTLSDACRELTEQMAEQQRKALSHDAWLTEQVNLAFEKFDSGKASFVDHDSAKAR
MAERKAKIRSRGQQ
Download Length: 285 bp
>AT182135 NZ_CP086334:c2781675-2781424 [Escherichia coli]
ATGCGTATTACCATAAAAAGATGGGGGAACAGTTCAGGTATGGTCATTCCTAATGTTGTGATGAAAGAACTTAACTTACG
GCCGGGGCAGAGCGTGGAGGCGCAAGTGAGCAACAATCAACTGATTCTGACACCCATCTCCAGGCGCTACTCGCTTGATG
AACTGCTGGCACAGTGTGACATGAACGCCACGGAACTTAGCGAGCAGGATGTCTGGGGTAAATCCACCCCTGCGGGTGAC
GAAATATGGTAA
ATGCGTATTACCATAAAAAGATGGGGGAACAGTTCAGGTATGGTCATTCCTAATGTTGTGATGAAAGAACTTAACTTACG
GCCGGGGCAGAGCGTGGAGGCGCAAGTGAGCAACAATCAACTGATTCTGACACCCATCTCCAGGCGCTACTCGCTTGATG
AACTGCTGGCACAGTGTGACATGAACGCCACGGAACTTAGCGAGCAGGATGTCTGGGGTAAATCCACCCCTGCGGGTGAC
GAAATATGGTAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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