Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2262196..2262467 Replicon chromosome
Accession NZ_CP065136
Organism Escherichia coli strain EE72d

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2262326..2262429 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2262196..2262467 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I2T83_RS10805 2258751..2259413 - 663 WP_000944256.1 exodeoxyribonuclease X -
I2T83_RS10810 2259437..2260093 - 657 WP_000011653.1 carbon-nitrogen hydrolase family protein -
I2T83_RS10815 2260195..2260425 - 231 WP_000916763.1 DNA polymerase III subunit theta -
I2T83_RS10820 2260564..2260938 + 375 WP_000204705.1 CopC domain-containing protein YobA -
I2T83_RS10825 2260942..2261814 + 873 WP_119163958.1 copper homeostasis membrane protein CopD -
I2T83_RS10830 2261827..2262168 + 342 WP_001520705.1 YebY family protein -
- 2262196..2262467 - 272 - - Antitoxin
- 2262326..2262429 + 104 - - Toxin
I2T83_RS10835 2262564..2263220 + 657 WP_001520704.1 protein-serine/threonine phosphatase -
I2T83_RS10840 2263221..2263412 - 192 WP_001296140.1 YebW family protein -
I2T83_RS10845 2263517..2263753 - 237 WP_001295499.1 DUF1480 family protein -
I2T83_RS10850 2263871..2265310 - 1440 WP_024166480.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T182079 NZ_CP065136:2262326-2262429 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT182079 NZ_CP065136:c2262467-2262196 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGCCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References