Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/Phd(antitoxin)
Location 2430503..2431050 Replicon chromosome
Accession NZ_CP065135
Organism Halomonas venusta strain PBH

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag IR195_RS11730 Protein ID WP_206047624.1
Coordinates 2430503..2430805 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag IR195_RS11735 Protein ID WP_095603088.1
Coordinates 2430793..2431050 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IR195_RS11700 2426140..2426628 - 489 WP_125748685.1 VOC family protein -
IR195_RS11705 2426752..2427543 - 792 WP_206047621.1 type I methionyl aminopeptidase -
IR195_RS11710 2427536..2427742 - 207 WP_125748691.1 ParD-like family protein -
IR195_RS11715 2427920..2429134 - 1215 WP_206047622.1 winged helix DNA-binding domain-containing protein -
IR195_RS11720 2429226..2429630 - 405 WP_125748698.1 DUF1801 domain-containing protein -
IR195_RS11725 2429713..2430300 - 588 WP_206047623.1 class I SAM-dependent methyltransferase -
IR195_RS11730 2430503..2430805 - 303 WP_206047624.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
IR195_RS11735 2430793..2431050 - 258 WP_095603088.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
IR195_RS11740 2431185..2431652 - 468 WP_206049785.1 pyridoxamine 5'-phosphate oxidase family protein -
IR195_RS11745 2431772..2432398 - 627 WP_206047625.1 LysE family translocator -
IR195_RS11750 2432647..2433609 + 963 WP_125748740.1 carbon starvation induced protein CsiD -
IR195_RS11755 2433674..2434888 + 1215 WP_146944894.1 L-2-hydroxyglutarate oxidase -
IR195_RS11760 2434964..2435479 - 516 WP_206047626.1 GNAT family N-acetyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-91)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-72)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11636.34 Da        Isoelectric Point: 4.4400

>T182069 WP_206047624.1 NZ_CP065135:c2430805-2430503 [Halomonas venusta]
MAEVIWTEPALQELDAIAEYIALDNPAAASHLVQDVFDKTERLENFPRSGRIPPELPNSVYREIVVPPCRIFYREDEKQI
LILYVMREERQLRAYMLGSS

Download         Length: 303 bp

>T182069 NZ_CP086295:2031606-2031905 [Burkholderia sp. B21-007]
ATGGACAAGATCAAGACCCGGCCGTGGGATTCGGCCGAACACCTGAAAACCGACGACGACATGGCCGACTACTTCGAGGC
CTGTCTGCAGGAAGGCGGCGACGACCCGGCCTTCATCGCGCATGCGCTCGGCGTGATCGCCCGCGCGCGCGGCATGTCGC
AGGTCTCGCGCGACGCGGGCCTGTCGCGCGAAGGGCTGTACAAGGCGCTGTCGCATGACGGCAATCCGAGCTTCGGCACG
ATCCTGAAAGTGATCAAGGCGCTCGGCCTGCAACTGCACGGCGCGAAGGCGCACGCGTGA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9887.46 Da        Isoelectric Point: 9.5103

>AT182069 WP_095603088.1 NZ_CP065135:c2431050-2430793 [Halomonas venusta]
MKVELVTNLKRQATKILADLHLSKEPVLITEHGKPSAYLVDVQDYEFMQRRLELLEGLSRGERAVLEGRTYSQSEAREKM
SKWLK

Download         Length: 258 bp

>AT182069 NZ_CP086295:2031285-2031602 [Burkholderia sp. B21-007]
ATGCCATACAGTGCACCTACATTCAGTATCCGGACCACCGACGTCTTCGACGCGTGGTTTGCCGGCCTGCAGGATCGCGT
CGCGAAGCGCCGCATCCAGGCGCGCATCGACCGTCTGTCGATGGGCAATCCAGGCGACTGGAAATCCGCCGGCTCCCCCG
TCGTCGAAACGCGTATCGATCACGGGCCCGGCTATCGCGTCTACTACGTCAGGCGCGGAACGATATGGGTGATCCTGCTC
TGCGGCGGCGACAAGTCGACGCAACAGGCGGACATCCGCGCCGCGCACGCGATGCTCGCGCGGCTCGACCTGGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References