Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-yefM/YoeB-RelB
Location 730512..731022 Replicon chromosome
Accession NZ_CP065135
Organism Halomonas venusta strain PBH

Toxin (Protein)


Gene name relB Uniprot ID -
Locus tag IR195_RS03545 Protein ID WP_206048757.1
Coordinates 730759..731022 (+) Length 88 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag IR195_RS03540 Protein ID WP_125745710.1
Coordinates 730512..730766 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IR195_RS03515 726461..727339 + 879 WP_206048753.1 hypothetical protein -
IR195_RS03520 727621..728472 + 852 WP_206048754.1 GNAT family N-acetyltransferase -
IR195_RS03525 728555..729088 + 534 WP_206048755.1 AAA family ATPase -
IR195_RS03530 729315..729695 + 381 WP_125753443.1 GFA family protein -
IR195_RS03535 729808..730350 + 543 WP_206048756.1 DinB family protein -
IR195_RS03540 730512..730766 + 255 WP_125745710.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
IR195_RS03545 730759..731022 + 264 WP_206048757.1 Txe/YoeB family addiction module toxin Toxin
IR195_RS03550 731069..732031 + 963 WP_206048758.1 ribonuclease Z -
IR195_RS03555 732205..733401 - 1197 WP_206048759.1 homoserine O-acetyltransferase -
IR195_RS03560 733477..734649 - 1173 WP_206048760.1 UbiH/UbiF/VisC/COQ6 family ubiquinone biosynthesis hydroxylase -
IR195_RS03565 734765..735613 + 849 WP_206048761.1 NAD-dependent protein deacetylase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(8-87)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10372.68 Da        Isoelectric Point: 7.9831

>T182068 WP_206048757.1 NZ_CP065135:730759-731022 [Halomonas venusta]
MSSRLLSWTDESWSDYLYWQTQDKKTLKRINKLINDARRSPFEGIGKPEPLKENLAGFWSRRIDDTDRLVYAVDDNAITI
ISCRYHY

Download         Length: 264 bp

>T182068 NZ_CP086295:2031285-2031602 [Burkholderia sp. B21-007]
ATGCCATACAGTGCACCTACATTCAGTATCCGGACCACCGACGTCTTCGACGCGTGGTTTGCCGGCCTGCAGGATCGCGT
CGCGAAGCGCCGCATCCAGGCGCGCATCGACCGTCTGTCGATGGGCAATCCAGGCGACTGGAAATCCGCCGGCTCCCCCG
TCGTCGAAACGCGTATCGATCACGGGCCCGGCTATCGCGTCTACTACGTCAGGCGCGGAACGATATGGGTGATCCTGCTC
TGCGGCGGCGACAAGTCGACGCAACAGGCGGACATCCGCGCCGCGCACGCGATGCTCGCGCGGCTCGACCTGGAGTGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9492.68 Da        Isoelectric Point: 5.0733

>AT182068 WP_125745710.1 NZ_CP065135:730512-730766 [Halomonas venusta]
MKIVSFTEARNSLKTVLDSVVNDADTAVITRRDSEDAVVMSLDYYNSLMETVHLLRSPANAEHLNRSIEQFKAGKVTHRD
LIDE

Download         Length: 255 bp

>AT182068 NZ_CP086295:2031606-2031905 [Burkholderia sp. B21-007]
ATGGACAAGATCAAGACCCGGCCGTGGGATTCGGCCGAACACCTGAAAACCGACGACGACATGGCCGACTACTTCGAGGC
CTGTCTGCAGGAAGGCGGCGACGACCCGGCCTTCATCGCGCATGCGCTCGGCGTGATCGCCCGCGCGCGCGGCATGTCGC
AGGTCTCGCGCGACGCGGGCCTGTCGCGCGAAGGGCTGTACAAGGCGCTGTCGCATGACGGCAATCCGAGCTTCGGCACG
ATCCTGAAAGTGATCAAGGCGCTCGGCCTGCAACTGCACGGCGCGAAGGCGCACGCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References