Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) chpB-mazE/PRK09812-MazE
Location 7427142..7427734 Replicon chromosome
Accession NZ_CP065053
Organism Massilia sp. CCM 8941

Toxin (Protein)


Gene name chpB Uniprot ID -
Locus tag IV454_RS32520 Protein ID WP_206089663.1
Coordinates 7427142..7427489 (-) Length 116 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag IV454_RS32525 Protein ID WP_206089664.1
Coordinates 7427483..7427734 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IV454_RS32495 7422705..7423469 - 765 WP_206089658.1 site-2 protease family protein -
IV454_RS32500 7423524..7424159 - 636 WP_206089659.1 threonylcarbamoyl-AMP synthase -
IV454_RS32505 7424156..7425040 - 885 WP_206089660.1 protease HtpX -
IV454_RS32510 7425187..7426020 - 834 WP_206089661.1 PHP domain-containing protein -
IV454_RS32515 7426100..7426975 - 876 WP_206089662.1 alpha/beta hydrolase -
IV454_RS32520 7427142..7427489 - 348 WP_206089663.1 type II toxin-antitoxin system ChpB family toxin Toxin
IV454_RS32525 7427483..7427734 - 252 WP_206089664.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
IV454_RS32530 7427873..7429021 - 1149 WP_206089665.1 hypothetical protein -
IV454_RS32535 7429211..7429735 + 525 WP_206089666.1 gamma carbonic anhydrase family protein -
IV454_RS32540 7429739..7430695 + 957 WP_206089667.1 Hsp33 family molecular chaperone HslO -
IV454_RS32545 7430697..7431131 + 435 WP_206089668.1 thioesterase family protein -
IV454_RS32550 7431138..7431671 + 534 WP_206089669.1 GNAT family N-acetyltransferase -
IV454_RS32555 7431790..7431978 - 189 WP_206089670.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(9-113)

Antitoxin

SpoVT-AbrB domain

(6-48)


Sequences

Toxin        


Download         Length: 116 a.a.        Molecular weight: 12186.12 Da        Isoelectric Point: 10.9254

>T182061 WP_206089663.1 NZ_CP065053:c7427489-7427142 [Massilia sp. CCM 8941]
VVKRAKFGRGDIILVNLDPTKGHERQGMRPALVLSTSVFNALGLALVAPIAQGGDFARHAGFAAPLTGSGTTIQGVVLVN
QVRMLDLEARAARRVETAPEFVVDDALARLRAITD

Download         Length: 348 bp

>T182061 NZ_CP086294:197238-197888 [Burkholderia sp. B21-007]
ATGGCTAATCACTATCCCAACCTCAACCCTGACAAGGCTCTGATATGGCGCATCGTTCACCGCGACAATCTGCAGTGGAT
TCTGGATAACGGCCTTCACTGTGGCAACAGCGCTGTGAAAGCGCCGGGCTGGGTGAGTATCGGCAACCCAGAACTGATCG
ACAAGCGTGCCAATCACCCGGTGCCGCGGCCACCGGGCGGCTTGTTGAACGACTACGTACCGTTCTACTTCACACCCTTT
TCGCCCATGCTGCGGAATATCCACACCGGCTGGGGCGGCATCCAGAAGCGATCGAATGAGGAAATCGTGATCCTGGTGTC
GAGTCTGTTCCATATTGTCGGGCAAGGCATGCCGTTTTTGTTTACCGATAGTCATGCCTATTACCAGTGGGCAAATTTTT
ACTCAGACGTGGCCTACCTCGACAAGATCGATTGGCCCTTGCTGCAACGGCGGGACTTCAAGCGCGATCCGGACGACCCT
GCTAAGTTTGAGCGCTATCAGGCCGAGGCGCTTATCCATCAACACTTGCCGGTGAGCGGACTTCTCGGCGTCGTGTGCTA
TACGGAACAATTGAAGCAACGCATTGAACAGGAGATTCAGGTCCGCAATCTGAATCTGCCGGTTTATGCCCGAACAGGGT
GGTATTTCTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 8902.30 Da        Isoelectric Point: 4.9431

>AT182061 WP_206089664.1 NZ_CP065053:c7427734-7427483 [Massilia sp. CCM 8941]
MELSVQKWGNSAAVRLPTELLGILKATLGDKLTVSVQNEGVLLKVKRPAYSLADLVAQCDPSAPEPVDMAAWSNVTPVGR
EAW

Download         Length: 252 bp

>AT182061 NZ_CP086294:197888-198964 [Burkholderia sp. B21-007]
ATGATTACATTCACTCAAGGCAATTTGTTGGAGGCTCGCGTTGAGGCGCTGGTCAACACTGTCAACACCGTTGGGGTGAT
GGGCAAGGGCATCGCGCTGATGTTCAAGGAGCGTTTTGACGAGAACTTTCGCCGTTACTCCGCTGCCTGCAAGGCCAAGG
AAGTACGGACCGGTAAGATGTTTGTGACGCCGGTGCATGAGCTGGATGGGCCGCGCTGGATCGTCAACTTCCCCACCAAG
CAACACTGGCGCGCACCGTCGCGCATGGAATGGATCATTGAGGGTTTGCAGGACCTGAGGCAATTCTTGATCGAGCAACA
AGTTAAGTCCATCGCCATCCCGCCGCTTGGCGCCGGTAACGGTGGCCTGGAGTGGGCCGATGTGCGCGAGCAGATCGAGC
TGACATTGGGGGATCTGGACATCGACATCGTTGTGTTCGAGCCCACTAAGCAATACCAGAACGTAGCCAAGCGCGCTGGG
GTCGAGAAGCTAACGCCGGCCCGAGCGCTGATTGCCGAGCTGGTGCGCCGCTACTGGGTGTTGGGCATGGAATGCAGCCT
CCTGGAGATTCAGAAGCTGGCGTGGTTTCTGGAGCGTGCGATTGAGCGCTACAACCCGGGTGACAACCCGCTGAACCTGC
AGTTTGCACCGCACAAGTACGGGCCCTATGCCAACCGGCTCGACCACCTACTGAACAATCTGGATGGCAGTTATTTGCAC
TCGCAGAAGCGCATCAGCGACGCCGATCCACTAGATGTGATCTGGTTTGACGACGAACGCAAGACTTTTGTGCAGACCTA
TCTCAAGAGCGAAGCCAAGGCCTACACGCAGGCACTGGAATCCACTGCGGCGCTGATCGATGGCTTTGAGTCGCCCTTTG
GCATGGAACTGTTGGCGACGGTGGACTGGCTGCTGGCCCGCGAAGGAGTCGCGCCCACGGTGCCGGCCTTGCGCGAAGGG
CTGCGCCATTGGCGAGGCGGCCCGGATGCCGGCGCGCGCAAGGATCGTCTCTTTGACGACCGGACGCTGGGCATTGCGCT
TGAACGCCTGACACAAGCAGCGCCCGCAATTGCGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References