Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) slvAT/RES(toxin)
Location 2481555..2482462 Replicon chromosome
Accession NZ_CP065053
Organism Massilia sp. CCM 8941

Toxin (Protein)


Gene name slvT Uniprot ID -
Locus tag IV454_RS11285 Protein ID WP_054265991.1
Coordinates 2481555..2482064 (-) Length 170 a.a.

Antitoxin (Protein)


Gene name slvA Uniprot ID -
Locus tag IV454_RS11290 Protein ID WP_054268080.1
Coordinates 2482061..2482462 (-) Length 134 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IV454_RS11270 2478980..2479426 + 447 WP_054265988.1 YiiD C-terminal domain-containing protein -
IV454_RS11275 2479470..2480666 + 1197 WP_054265989.1 acetyl-CoA C-acyltransferase -
IV454_RS11280 2480740..2481519 + 780 WP_206091525.1 enoyl-CoA hydratase -
IV454_RS11285 2481555..2482064 - 510 WP_054265991.1 RES family NAD+ phosphorylase Toxin
IV454_RS11290 2482061..2482462 - 402 WP_054268080.1 hypothetical protein Antitoxin
IV454_RS11295 2482696..2483658 - 963 WP_206091526.1 hypothetical protein -
IV454_RS11300 2483666..2484994 - 1329 WP_206091527.1 sphingomyelin phosphodiesterase -
IV454_RS11305 2485051..2487060 - 2010 WP_206091528.1 neutral/alkaline ceramidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(10-158)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 170 a.a.        Molecular weight: 18369.60 Da        Isoelectric Point: 4.2085

>T182060 WP_054265991.1 NZ_CP065053:c2482064-2481555 [Massilia sp. CCM 8941]
MILTPLNAVAYRVHQPKWSFAPTSGAGAGAYGGRANRPGVNALYLSLELETALAEYQQLDALLPPGLMVSYNVSINAIVD
FRGGFTSGWDALWQDFYCDWRNMHFNQGIEPPSWVIGDQVLAADAKGILFNSAITGGENLVIYTDALTGADAINVYDPNN
DLPKNQSSW

Download         Length: 510 bp

>T182060 NZ_CP086292:2592429-2592710 [Burkholderia ambifaria]
ATGACCTTTGAGCTTGCCTTTCTCGAACCTGCGTTGAAGGAGTGGAAAAAGCTCGATCGCACCATCCGCGACCAGTTCAA
ATCCCGACTCGCCGAGCGCCTCGAGAATCCCCGCATTGCGTCGGCCAAGCTGCATGGCCATCCGGATCGCTACAAGATCA
AGCTGCGCAGCGTCGGCTACCGACTCGTCTACGAAGTGCGCGATACGGAAGTGATCGTACTGGTTGTCGCAGTCGGTCGC
CGTGACCGCGATGCCGTCTATCTTGCCGCGATGAAGCGGTAG

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 15030.12 Da        Isoelectric Point: 6.7181

>AT182060 WP_054268080.1 NZ_CP065053:c2482462-2482061 [Massilia sp. CCM 8941]
MTVPAGEAVPVFDRNFDEFMNFLNSEASPSISPKRFGLVFRVDMQTLAAQAHVHRNTVRLAPDTETIQSYLRESVRVMCA
ATDISGSIEKAIYWFKNHPLPTFDYKTPQDLVSEKRTDALIKYIQSLQAGYIG

Download         Length: 402 bp

>AT182060 NZ_CP086292:2592191-2592439 [Burkholderia ambifaria]
ATGCCTCACACCATTCTGGCAAATGTTACGGCGAGCGTTTCGGAACTGAAGCGCAATCCGATGGGTACCGTCGCGGCGGG
CGAGGGCTTTCCGGTTGCGATTCTGAATCACAACGAGCCCGCGTTCTATTGCATCCCGGCGAAGACGTGGGAAGCGATGG
TCGAACGTCTCGAAGATATAGAAGACAACGCGCTTGCCAATACGCGTGCGAAGGACAAGGTCGTCAAGGTCAAGCTGAAT
GACCTTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References