Detailed information of TA system TA182056

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/-
• Location: 3385096..3385749
• Replicon: chromosome
• Accession: NZ_CP065051
• Organism: Acinetobacter baumannii strain 2016GDAB1

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: -
• Locus tag: IVB58_RS15945
• Protein ID: WP_000607096.1
• Coordinates: 3385096..3385485 (-)
• Length: 130 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: V5V966
• Locus tag: IVB58_RS15950
• Protein ID: WP_001288210.1
• Coordinates: 3385492..3385749 (-)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
IVB58_RS15930 (IVB58_15880)	3380214..3382409	-	2196	WP_001158905.1	TRAP transporter large permease subunit	-
IVB58_RS15935 (IVB58_15885)	3382597..3383163	-	567	WP_000651536.1	rhombosortase	-
IVB58_RS15940 (IVB58_15890)	3383241..3384326	-	1086	WP_000049106.1	hypothetical protein	-
IVB58_RS15945 (IVB58_15895)	3385096..3385485	-	390	WP_000607096.1	hypothetical protein	Toxin
IVB58_RS15950 (IVB58_15900)	3385492..3385749	-	258	WP_001288210.1	succinate dehydrogenase assembly factor 2	Antitoxin
IVB58_RS15955 (IVB58_15905)	3385937..3387109	+	1173	WP_001190543.1	acyl-CoA dehydrogenase family protein	-
IVB58_RS15960 (IVB58_15910)	3387158..3388648	-	1491	WP_000415137.1	NAD(P)/FAD-dependent oxidoreductase	-
IVB58_RS15965 (IVB58_15915)	3388830..3389207	-	378	WP_001216380.1	50S ribosomal protein L17	-
IVB58_RS15970 (IVB58_15920)	3389226..3390233	-	1008	WP_000198631.1	DNA-directed RNA polymerase subunit alpha	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Flavinator of succinate dehydrogenase (10-82)

Sequences

Toxin

Protein

• Length: 130 a.a.
• Molecular weight: 15583.80 Da
• Isoelectric Point: 10.4637

>T182056 WP_000607096.1 NZ_CP065051:c3385485-3385096 [Acinetobacter baumannii]
MINHSNFKLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYHSQNTI
SRVKILKIIDYQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLH

Nucleotide

• Length: 390 bp

>T182056 NZ_CP086292:c1218165-1217749 [Burkholderia ambifaria]
GTGTTTTTGATTGATACGAACGTCATCAGCGAGATCAGAAAGGGCAAGCGAACCAACCGCGGCGTGCGCGCGTTTTTCAC
GCAGGCGGAGGCCGACGCGAGCCCGCTTTACCTGTCGGTCGTGACGGTGGCCGAACTGCGGCGCGGCGTCGACCTGATCC
GTCATCGCGGCGATCATCCGCAGGCGTCGGCGCTCGAGGCATGGATGGCGACGATCCTGTCCGGCTATGCGTCGAACATC
CTGCCGGTCGATATCGAGACCGCCCAGATGTGGGGCCATTTGCGCGTGCCCGATCCGGCGCACGCCCTCGATCACCTGAT
CGCGGCCACCGCGCTGATCAACGATTTGACGGTCGTTACCCGCAATGTCGACGATTTCGCTCGCACCGGCGTCCGGCTGC
TGAACCCGTTCGATTGA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 10318.77 Da
• Isoelectric Point: 4.6150

>AT182056 WP_001288210.1 NZ_CP065051:c3385749-3385492 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Nucleotide

• Length: 258 bp

>AT182056 NZ_CP086292:c1218388-1218152 [Burkholderia ambifaria]
ATGGCAAATCTTCTGGTGCGTAACGTGGATGACAGTATCGTTCAGAGCCTGCGCGAGCAGGCCGCGGCCAACGGCAGGAG
CGCCGAGGCCGAACATCGGGCCATTCTGGCCGAGGCGCTCGGCCGGCCGAAGCGACGGACATTCGCGCACGTGCTGATGA
GCATGCCGGACGTCGGCGAAGACGCGGATTTCCAACGTGTTCAGGATTCCGGCGAGGTCAGGCGTGTTTTTGATTGA

Structures

Antitoxin

• AlphaFold DB: A0A7U4BQM7