Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) ykfI-yfjZ/CbtA-CbeA
Location 3105995..3106720 Replicon chromosome
Accession NZ_CP065044
Organism Pectobacterium aroidearum strain L6

Toxin (Protein)


Gene name ykfI Uniprot ID -
Locus tag I2D83_RS13945 Protein ID WP_181838212.1
Coordinates 3105995..3106315 (-) Length 107 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag I2D83_RS13950 Protein ID WP_205946720.1
Coordinates 3106385..3106720 (-) Length 112 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I2D83_RS13915 3101186..3101389 - 204 WP_015840819.1 protein DsrB -
I2D83_RS13920 3101600..3103015 + 1416 WP_205946717.1 diguanylate cyclase -
I2D83_RS13925 3103288..3103506 + 219 WP_180777774.1 KTSC domain-containing protein -
I2D83_RS13930 3103734..3104090 + 357 WP_205946718.1 hypothetical protein -
I2D83_RS13935 3104724..3104921 - 198 WP_205946719.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein -
I2D83_RS13940 3105044..3105877 - 834 WP_205948188.1 DUF4942 domain-containing protein -
I2D83_RS13945 3105995..3106315 - 321 WP_181838212.1 TA system toxin CbtA family protein Toxin
I2D83_RS13950 3106385..3106720 - 336 WP_205946720.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
I2D83_RS13955 3106760..3107233 - 474 WP_205568484.1 DNA repair protein RadC -
I2D83_RS13960 3107439..3108044 - 606 WP_205568485.1 hypothetical protein -
I2D83_RS13965 3108073..3108627 - 555 WP_094431875.1 hypothetical protein -
I2D83_RS13970 3108925..3109800 - 876 WP_205568487.1 50S ribosome-binding GTPase -
I2D83_RS13975 3109874..3110731 - 858 WP_205946721.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-105)

Antitoxin

Antitoxin CbeA

(7-106)


Sequences

Toxin        


Download         Length: 107 a.a.        Molecular weight: 12098.83 Da        Isoelectric Point: 4.6104

>T182039 WP_181838212.1 NZ_CP065044:c3106315-3105995 [Pectobacterium aroidearum]
MQTIPEIPSREEQSCPSPIAVWQQLLTYLLEKHYGLTLNDTPFCEENVIQAHIDAGVTLVNAVNFLVEKYELVRIDRDGF
NWQEQSPFLTAVDILRARRATGLLKA

Download         Length: 321 bp

>T182039 NZ_CP086287:286281-286556 [Citrobacter freundii]
ATGAAGGAAAAAGTGTTGTCTTTACGCAAAAAGCAAAAGAACACGCTGGATCAGCTTTTTAAAGCACCGACGCCGCAGGG
AATCAAGTGGTCGGAAATTGAGTCACTGATCAAGGCGTTAGGTGGCGAAATCAAAGAAGGACGAGGCTCGCGATGTAAAT
TTCTTTTAAATAAGAGCATTGCGAGTTTTCATAGACCACATCCTTCTCCGGATACAGATAAAGGCGCGGTCGAAAACGTA
CGTGACTGGTTAACAAGTATAGGGGTAAAACCATGA

Antitoxin


Download         Length: 112 a.a.        Molecular weight: 12482.15 Da        Isoelectric Point: 5.1279

>AT182039 WP_205946720.1 NZ_CP065044:c3106720-3106385 [Pectobacterium aroidearum]
MPSSETPEWGLKRAVMPQFGARLVQEGHYLHYLADRASIVGTFSETEARHLERCFPEMIKQLEQKLCSGELNPRQQGCIT
LHCNEWTCEADTLGSFGYVYIAIYPSAAAAE

Download         Length: 336 bp

>AT182039 NZ_CP086287:286553-286912 [Citrobacter freundii]
ATGATCAAACCCAAAACGCCAAACTCAATGGAAATCGCCGGTCAACCTGCGGTAATTAATTATGTCCCTGAGCTTAATGC
GTTTCGCGGTAAGTTCCTGGGATTGTCAGGCTATTGTGATTTTGTCTCTGACAGCATTCAGGGGCTGCAAAAAGAGGGGG
AGATCTCCTTACGAGAGTATCTTGATGATTGCTCTGCCGCAGGGATAGAACCTTACGCAAACCCGGAAAAGCTGAAGACG
TTTACTCTGCGCTATCCAGAGTCTTTCGGAGAACGTTTAAGTTTTGCGGCAGCGGAAGAACAGGTATCAGTCAATACATG
GATCATCGAAACGCTCAGCAAAAGTCTCAAACAGGCATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References