Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) stbDE/ParE-DnaT
Location 4814615..4815146 Replicon chromosome
Accession NZ_CP065036
Organism Pectobacterium parmentieri strain PB20

Toxin (Protein)


Gene name stbE Uniprot ID -
Locus tag PB20LOC_RS22010 Protein ID WP_103808553.1
Coordinates 4814859..4815146 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name stbD Uniprot ID -
Locus tag PB20LOC_RS22005 Protein ID WP_103808552.1
Coordinates 4814615..4814869 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PB20LOC_RS21980 4809833..4810423 - 591 WP_011091952.1 DnaA initiator-associating protein DiaA -
PB20LOC_RS21985 4810465..4810821 - 357 WP_012822117.1 YraN family protein -
PB20LOC_RS21990 4810818..4812836 - 2019 WP_014698522.1 penicillin-binding protein activator -
PB20LOC_RS21995 4812898..4813785 + 888 WP_014698523.1 16S rRNA (cytidine(1402)-2'-O)-methyltransferase -
PB20LOC_RS22005 4814615..4814869 + 255 WP_103808552.1 plasmid stabilization protein Antitoxin
PB20LOC_RS22010 4814859..4815146 + 288 WP_103808553.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PB20LOC_RS22015 4815328..4816116 + 789 WP_033072300.1 4,5-DOPA dioxygenase extradiol -
PB20LOC_RS22020 4816204..4817364 - 1161 WP_103808554.1 glutathionylspermidine synthase family protein -
PB20LOC_RS22025 4817376..4818044 - 669 WP_012822126.1 DUF1190 family protein -
PB20LOC_RS22030 4818328..4819719 - 1392 WP_012822127.1 outer membrane channel protein TolC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-87)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 10997.89 Da        Isoelectric Point: 10.7148

>T182014 WP_103808553.1 NZ_CP065036:4814859-4815146 [Pectobacterium parmentieri]
MTYKLKFVPSAMKEWKKLGHPVREQFKKKLVERLENPRVPSAQLHGRKDQYKIKLKSAGYRLVYLVQDETITVMVMGVGK
REGSQVYSDTQGRSA

Download         Length: 288 bp

>T182014 NZ_CP086259:3922102-3922644 [Escherichia coli]
ATGGTCGACAAGCATGAAGAGATTACTCTGCCCATAGTCCTCTCCTGTAATTATCAGTCTGATATTACTTATCCTGGGCA
AAAACAGTTTGATTGCGGTAACCCTGTTATCGATAAATTTGTACGCGCATCGCTAAAGAAAAGTGTGCGTAATAGCGACT
GTGCGGCTAAAGCACTTATTGACAGACAAAGTGGTGAACTGATCGGCATCTGTACTTTTACGGCATATTCGCTGGAAAAA
CAACGCGTTTCTGGCGTCCTTCAGGGTTCACAACCTTCAGAAATTGGTGTTGTCAGATTAGTCATGTTGGGGGTAGCACG
GAAGTATCAAAAGCGGGGCTTTGGTCAGGACCTACTATGTGATTTTTTTGAACATGTAAAAATAATTCACCAGGCATTAC
CAATTAAAGGGGTTTATCTTGATGCTGACCCTGCCGCCATTAATTTTTATGCTCGTCTCGGCTTTGTTCAGCTTTCAGCG
ACACCAAATGCTTTTGGTGCTGTACCTATGTTTTTGGCGATTCAGCATATTCTCGCGGCTTAG

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9284.50 Da        Isoelectric Point: 3.7947

>AT182014 WP_103808552.1 NZ_CP065036:4814615-4814869 [Pectobacterium parmentieri]
MAFNILTNTVASITELKRDPMGTVRSAEGETIAILNRNEPAFYCVPPAMFAYLMELAEDAELGRTVDDRMSELADAEEIS
LDDL

Download         Length: 255 bp

>AT182014 NZ_CP086259:3921807-3922118 [Escherichia coli]
ATGCCTGGAAAAACAGCCACTCTACCCGATGTCGATAAAACGCTGAAAAATGCGCGGGTCGAACTCAAAACTAGTCCCGA
CGCCAAAAACAAACTTCGTGAAGCTGCGCAAGCCGTTGGGGTAGATTTAAGCGCTTTTATTTTGAGCGCTGCTATGGAAC
GCGCCGAAAGTGTGCTTGATAACCAACGTCGCCGTGAGCTTTCGAATCAAAGCTGGGAACTGATGAACCAACTCATCGCT
GAACCTGCTCAACCGACGCTCGCCCTCAAGGCGTTAATGAAAAGGAAAAACAGCGATGGTCGACAAGCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References