Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) ykfI-yfjZ/CbtA-CbeA
Location 3108158..3108883 Replicon chromosome
Accession NZ_CP065036
Organism Pectobacterium parmentieri strain PB20

Toxin (Protein)


Gene name ykfI Uniprot ID -
Locus tag PB20LOC_RS14095 Protein ID WP_103808729.1
Coordinates 3108158..3108478 (-) Length 107 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag PB20LOC_RS14100 Protein ID WP_103808730.1
Coordinates 3108548..3108883 (-) Length 112 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PB20LOC_RS14075 3104001..3105320 + 1320 WP_103808725.1 site-specific integrase -
PB20LOC_RS14080 3105392..3106441 - 1050 WP_103808726.1 macro domain-containing protein -
PB20LOC_RS14085 3106455..3107102 - 648 WP_103808727.1 DUF4433 domain-containing protein -
PB20LOC_RS14090 3107207..3108040 - 834 WP_103808728.1 DUF4942 domain-containing protein -
PB20LOC_RS14095 3108158..3108478 - 321 WP_103808729.1 TA system toxin CbtA family protein Toxin
PB20LOC_RS14100 3108548..3108883 - 336 WP_103808730.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
PB20LOC_RS14105 3108923..3109396 - 474 WP_103808731.1 DNA repair protein RadC -
PB20LOC_RS14110 3109481..3109714 - 234 WP_040034648.1 membrane protein -
PB20LOC_RS14115 3109732..3110205 - 474 WP_103808732.1 hypothetical protein -
PB20LOC_RS14120 3110241..3110810 - 570 WP_196398879.1 hypothetical protein -
PB20LOC_RS14125 3110992..3111690 - 699 WP_121301470.1 DeoR family transcriptional regulator -
PB20LOC_RS14130 3112060..3112935 - 876 WP_196398866.1 GTPase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-105)

Antitoxin

Antitoxin CbeA

(7-106)


Sequences

Toxin        


Download         Length: 107 a.a.        Molecular weight: 12066.79 Da        Isoelectric Point: 4.5971

>T182013 WP_103808729.1 NZ_CP065036:c3108478-3108158 [Pectobacterium parmentieri]
MQTIPAIPSREDNPCPSPIAAWQQLLTYLLEKHYGLTLNDTPFCEENVIQEHIDAGITLVNAVNFLVEKYELVRIDRDGF
NWQEQSPFLTAVDILRARRATGLLKA

Download         Length: 321 bp

>T182013 NZ_CP086259:3888130-3888348 [Escherichia coli]
ATGTCCGAAAAACCTTTAACGAAAACCGATTATTTAATGCGTTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGTGT
TATCGAGAAAAATAAATACGAATTATCAGATAATGAACTGGCGGTATTTTACTCAGCCGCAGATCACCGCCTCGCCGAAT
TGACCATGAATAAACTATACGACAAGATCCCTTCCTCAGTATGGAAATTTATTCGCTAA

Antitoxin


Download         Length: 112 a.a.        Molecular weight: 12471.28 Da        Isoelectric Point: 6.6869

>AT182013 WP_103808730.1 NZ_CP065036:c3108883-3108548 [Pectobacterium parmentieri]
MPSSDTPEWGLKCAVTPRFGARLVQEGHRLHYLADRASIVGTFSKTEAQSLERCFPELIKLLEQKLRMGELNPRQQNCVT
LHCNEWICEADTLGSVGYVYIVIYPSSAATQ

Download         Length: 336 bp

>AT182013 NZ_CP086259:3887730-3888104 [Escherichia coli]
ATGGATGAATACTCACCCAAAAGACATGATATCGCACAGCTTAAGTTTCTCTGTGAAACCCTGTATCATGACTGCCTTGC
AAACCTTGAAGAAAGCAATCATGGCTGGGTTAACGACCCAACCTCGGCGATCAACCTCCAGTTGAATGAACTGATTGAGC
ATATTGCGACCTTCGCACTTAATTACAAAATTAAGTATAATGAAGACAATAAGCTCATTGAGCAGATCGACGAATATCTG
GATGACACCTTTATGTTGTTCAGTAGTTATGGTATTAATATGCAGGATCTTCAGAAATGGCGGAAGTCAGGTAATCGACT
ATTCCGTTGTTTTGTCAATGCGACGAAAGAGAATCCTGCGAGTTTATCTTGTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References