Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type IV Classification (family/domain) ykfI-yfjZ/CbtA-CbeA
Location 1031973..1032698 Replicon chromosome
Accession NZ_CP065036
Organism Pectobacterium parmentieri strain PB20

Toxin (Protein)


Gene name ykfI Uniprot ID -
Locus tag PB20LOC_RS04780 Protein ID WP_103808442.1
Coordinates 1031973..1032293 (-) Length 107 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag PB20LOC_RS04785 Protein ID WP_103808441.1
Coordinates 1032363..1032698 (-) Length 112 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PB20LOC_RS04750 1027176..1027466 - 291 WP_196398873.1 transposase -
PB20LOC_RS04755 1027532..1027861 + 330 Protein_921 IS30 family transposase -
PB20LOC_RS04760 1028035..1028664 - 630 WP_103808445.1 hypothetical protein -
PB20LOC_RS04765 1029095..1030309 - 1215 WP_103808444.1 tyrosine-type recombinase/integrase -
PB20LOC_RS04770 1030670..1030840 - 171 WP_155116481.1 hypothetical protein -
PB20LOC_RS04775 1031022..1031855 - 834 WP_103808443.1 DUF4942 domain-containing protein -
PB20LOC_RS04780 1031973..1032293 - 321 WP_103808442.1 TA system toxin CbtA family protein Toxin
PB20LOC_RS04785 1032363..1032698 - 336 WP_103808441.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
PB20LOC_RS04790 1032735..1033208 - 474 WP_121301511.1 DNA repair protein RadC -
PB20LOC_RS04795 1033292..1033525 - 234 WP_103808798.1 hypothetical protein -
PB20LOC_RS04800 1033543..1034016 - 474 WP_103808799.1 hypothetical protein -
PB20LOC_RS04805 1034052..1034621 - 570 WP_196398877.1 hypothetical protein -
PB20LOC_RS04810 1034803..1035501 - 699 WP_121247005.1 DeoR family transcriptional regulator -
PB20LOC_RS04815 1035871..1036746 - 876 WP_103808734.1 GTPase family protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(1-105)

Antitoxin

(7-106)


Sequences


Toxin        


Download         Length: 107 a.a.        Molecular weight: 12035.73 Da        Isoelectric Point: 4.7768

>T182010 WP_103808442.1 NZ_CP065036:c1032293-1031973 [Pectobacterium parmentieri]
MQTSPAIPPREDNPCPSPIAVWQQLLTYLLEKHYGLTLNDTPFCEENVIQEHIDAGITLANAVNFLVEKYELVRIDRNGF
NWQEQSPFLTAVDVLRARRATGLLKA

Download         Length: 321 bp

>T182010 NZ_CP086259:c2513393-2512071 [Escherichia coli]
ATGCCTAAACTTGTCACTTGGATGAACAACCAGCGGGTAGGCGAGTTAACGAAGTTAGCCAACGGCGCGCACACCTTTAA
GTATGCACCGGAGTGGTTAGCCAGCCGTTATGCCAGACCGTTGTCACTTTCGCTGCCATTGCAGAGGGGGAATATCACCT
CAGATGCCGTATTTAACTTCTTCGATAACCTGTTACCCGATAGCCCGATTGTACGTGACCGGATCGTTAAACGTTATCAT
GCTAAATCCAGACAACCGTTTGATTTATTGTCAGAAATAGGGCGAGACAGCGTTGGTGCCGTAACGTTATTACCCGAAAA
TGAAACCATAACGCGCCCGATAATGGCATGGGAAAAGCTTACTGAAGCCAGGCTTGAAGAAGTATTAACGGCTTATAAAG
CAGATATCCCTCTGGGCATGATTAGAGAAGAAAATGACTTTCGCATCTCGGTTGCTGGCGCGCAGGAGAAGACAGCGCTG
CTTAGAATAGGCAATGACTGGTGCATTCCGAAAGGAATAACGCCGACGACGCACATCATTAAATTACCGATTGGCGAAAT
CAGGCAGCCCAATGCGACGCTCGATCTCAGCCAAAGCGTTGATAATGAGTATTACTGTCTGCTGCTGGCGAAAGAACTTG
GGTTGAGTGTTCCGGACGCAGAAATCATTAAAGCGGGAAGGGTGCGCGCGTTAGCGGTCGAACGTTTTGACAGGCGTTGG
AATACTGAGCGAACGGTTTTACTTCGCTTGCCACAGGAGGATATGTGTCAGACATTCGGTTTACCTTCATCTGTGAAATA
TGAATCAGATGGAGGCCCAGGCATCGCGCGGATCATGGCGTTTTTGATGGGGTCCAGCGAGGCGCTTCGCGATCGTTATG
ATTTTATGAAATTCCAAGTCTTCCAGTGGTTGATTGGCGCAACGGATGGCCATGCAAAAAACTTCTCCGTATTTATTCAG
GCTGGCGGCAGTTATCGACTCACGCCATTTTACGACATCATTTCAGCATTTCCGGTCCTTGGCGGTACGGGAATACACAT
CAGCGATCTCAAACTGGCAATGGGGCTTAACGCATCCAAAGGCAAAAAAACGGCAATCGATAAAATTTATCCGCGACATT
TTTTGGCGACAGCAAAGGTGCTGAGATTCCCGGAAGTGCAGATGCATGAAATCCTAAGTGACTTTGCCAGAATGATTCCG
GCAGCACTGGATAACGTGAAGACTTCATTACCGACAGATTTTCCGGAGAACGTGGTGACGGCAGTTGAAACCAATGTGTT
GAGGTTGCATGGACGGTTAAGCCGAGAATACGGTAGTAAGTGA

Antitoxin


Download         Length: 112 a.a.        Molecular weight: 12643.32 Da        Isoelectric Point: 5.5351

>AT182010 WP_103808441.1 NZ_CP065036:c1032698-1032363 [Pectobacterium parmentieri]
MPSSDTPEWGLKCAITPRFGARLVQEGHRLHYLEDRASIVGTFSEMEAHHLEEIFPELIKQLEQKLRSGELNPRQRGCVT
LYCNEWTCEADTLGSFGYVYIVIYPTSAATH

Download         Length: 336 bp

>AT182010 NZ_CP086259:c2513659-2513393 [Escherichia coli]
ATGATGAGCTTTCAGAAGATCTATAGCCCAACGCAATTAGCGAATGCAATGAAACTGGTTCGCCAGCAAAATGGCTGGAC
GCAGAGCGAGCTGGCGAAAAAAATTGGCATTAAGCAGGCGACAATTTCCAATTTCGAAAACAACCCTGACAATACCACGC
TCACGACATTTTTTAAGATTTTACAGTCGCTTGAACTCTCAATGACACTATGCGACACGAAAAATGCCTCGCCAGAATCA
ACAGAACAGCAAGATCTGGAGTGGTAA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References