Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | IV | Classification (family/domain) | cptAB/Cpta(toxin) |
Location | 443477..444137 | Replicon | chromosome |
Accession | NZ_CP065036 | ||
Organism | Pectobacterium parmentieri strain PB20 |
Toxin (Protein)
Gene name | cptA | Uniprot ID | A0A8B3EZX7 |
Locus tag | PB20LOC_RS02130 | Protein ID | WP_012822581.1 |
Coordinates | 443724..444137 (+) | Length | 138 a.a. |
Antitoxin (Protein)
Gene name | cptB | Uniprot ID | A0A0H3I0G9 |
Locus tag | PB20LOC_RS02125 | Protein ID | WP_012822580.1 |
Coordinates | 443477..443743 (+) | Length | 89 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
PB20LOC_RS02105 | 439469..440473 | - | 1005 | WP_103807861.1 | substrate-binding domain-containing protein | - |
PB20LOC_RS02110 | 440527..441135 | - | 609 | WP_014698756.1 | HD domain-containing protein | - |
PB20LOC_RS02115 | 441546..442193 | + | 648 | WP_012822578.1 | hemolysin III family protein | - |
PB20LOC_RS02120 | 442248..443249 | - | 1002 | WP_012822579.1 | tRNA-modifying protein YgfZ | - |
PB20LOC_RS02125 | 443477..443743 | + | 267 | WP_012822580.1 | FAD assembly factor SdhE | Antitoxin |
PB20LOC_RS02130 | 443724..444137 | + | 414 | WP_012822581.1 | protein YgfX | Toxin |
PB20LOC_RS02135 | 444363..445298 | + | 936 | WP_012822582.1 | 23S rRNA (adenine(1618)-N(6))-methyltransferase RlmF | - |
PB20LOC_RS02140 | 445386..445709 | - | 324 | WP_012822583.1 | hypothetical protein | - |
PB20LOC_RS02145 | 445738..446256 | - | 519 | WP_012822584.1 | flavodoxin FldB | - |
PB20LOC_RS02150 | 446584..447600 | + | 1017 | WP_012822585.1 | methionine ABC transporter ATP-binding protein | - |
PB20LOC_RS02155 | 447593..448261 | + | 669 | WP_012822586.1 | ABC transporter permease | - |
PB20LOC_RS02160 | 448279..449097 | + | 819 | WP_033071942.1 | MetQ/NlpA family ABC transporter substrate-binding protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 138 a.a. Molecular weight: 16259.20 Da Isoelectric Point: 10.7923
>T182009 WP_012822581.1 NZ_CP065036:443724-444137 [Pectobacterium parmentieri]
VAQWQCDLRVSWRMQLLSLVVHGLLVLLILLAPWPDGYAWLWLCLVTMVMFGFIRSQRNIKSRQGCITLLSETTLNWRQQ
EWRIVKRPWLLKNGVLLALQSANGKDKQQLWLASDSMGDDEWRHLRQLLLQQKHWAR
VAQWQCDLRVSWRMQLLSLVVHGLLVLLILLAPWPDGYAWLWLCLVTMVMFGFIRSQRNIKSRQGCITLLSETTLNWRQQ
EWRIVKRPWLLKNGVLLALQSANGKDKQQLWLASDSMGDDEWRHLRQLLLQQKHWAR
Download Length: 414 bp
>T182009 NZ_CP086259:c2170422-2170315 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGACTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGGATTATTACCGCAGCGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA
ATGACGCTCGCGCAGTTTGCCATGACTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGGATTATTACCGCAGCGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA
Antitoxin
Download Length: 89 a.a. Molecular weight: 10519.99 Da Isoelectric Point: 5.1392
>AT182009 WP_012822580.1 NZ_CP065036:443477-443743 [Pectobacterium parmentieri]
MEIDNKSRIHWACRRGMRELDIAIMPFFEHDYDTLNDIDKRTFVRLLQSDDPDLFNWLMNHGEPEDGELKRMISLIQTRN
KDRGPVAM
MEIDNKSRIHWACRRGMRELDIAIMPFFEHDYDTLNDIDKRTFVRLLQSDDPDLFNWLMNHGEPEDGELKRMISLIQTRN
KDRGPVAM
Download Length: 267 bp
>AT182009 NZ_CP086259:2170469-2170535 [Escherichia coli]
TGTCTGGTTTCAAGATTAGCCCCCGTTTTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT
TGTCTGGTTTCAAGATTAGCCCCCGTTTTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A8B3EZX7 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A0H3I0G9 |