Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 129192..129719 Replicon chromosome
Accession NZ_CP065036
Organism Pectobacterium parmentieri strain PB20

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag PB20LOC_RS00700 Protein ID WP_039517502.1
Coordinates 129444..129719 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag PB20LOC_RS00695 Protein ID WP_103808671.1
Coordinates 129192..129440 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PB20LOC_RS00660 125235..125393 + 159 WP_155242703.1 hypothetical protein -
PB20LOC_RS00665 125540..126373 + 834 WP_103808667.1 hypothetical protein -
PB20LOC_RS00670 126431..126781 + 351 WP_005974477.1 hypothetical protein -
PB20LOC_RS00675 126904..127377 + 474 WP_103808668.1 DNA repair protein RadC -
PB20LOC_RS00680 127417..127752 + 336 WP_103808669.1 type IV toxin-antitoxin system YeeU family antitoxin -
PB20LOC_RS00685 127811..128131 + 321 WP_103808670.1 TA system toxin CbtA family protein -
PB20LOC_RS00690 128249..129082 + 834 Protein_136 DUF4942 domain-containing protein -
PB20LOC_RS00695 129192..129440 + 249 WP_103808671.1 ribbon-helix-helix domain-containing protein Antitoxin
PB20LOC_RS00700 129444..129719 + 276 WP_039517502.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PB20LOC_RS00705 129767..130279 + 513 WP_103808672.1 AAA family ATPase -
PB20LOC_RS00710 130586..131706 - 1121 Protein_140 IS3 family transposase -
PB20LOC_RS00715 131778..132946 + 1169 WP_103808047.1 IS3 family transposase -
PB20LOC_RS00720 132921..133232 - 312 WP_103808046.1 hypothetical protein -
PB20LOC_RS00725 133714..133976 - 263 Protein_143 PAAR domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - mgtB / hcp 107012..249782 142770


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(9-43)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 11028.25 Da        Isoelectric Point: 5.5034

>T182007 WP_039517502.1 NZ_CP065036:129444-129719 [Pectobacterium parmentieri]
MEIRWTQKAQDDLERIYGFASQYSRHHADEVLDRLIIGTTGIADHPRIGVSQTRYEPREVRKILFDDYEVHYEIQHDTIY
IVDLWHTREDR

Download         Length: 276 bp

>T182007 NZ_CP086259:c2169351-2169244 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCGGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9007.39 Da        Isoelectric Point: 8.7560

>AT182007 WP_103808671.1 NZ_CP065036:129192-129440 [Pectobacterium parmentieri]
MGQPAKQTISAQIPAELAAAVESLAIELDRSKSWVIKEALTAMIEERERRHQRVLKGLADVDAGRVVSHADVIDFANKLK
KS

Download         Length: 249 bp

>AT182007 NZ_CP086259:2169399-2169465 [Escherichia coli]
GTTCTGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References