Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1820407..1820552 Replicon chromosome
Accession NZ_CP065034
Organism Klebsiella pneumoniae strain 2016-1400

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1820443..1820545 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1820407..1820552 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GOY40_RS08830 1815537..1817597 + 2061 WP_032444542.1 oligopeptidase B -
GOY40_RS08835 1817601..1818260 - 660 WP_002911407.1 exodeoxyribonuclease X -
GOY40_RS08840 1818339..1818569 - 231 WP_002911406.1 DNA polymerase III subunit theta -
GOY40_RS08845 1818682..1819056 + 375 WP_004151448.1 CopC domain-containing protein YobA -
GOY40_RS08850 1819060..1819929 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
GOY40_RS08855 1819946..1820284 + 339 WP_002911404.1 YebY family protein -
- 1820407..1820552 - 146 - - Antitoxin
- 1820443..1820545 + 103 - - Toxin
GOY40_RS08860 1820920..1821063 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
GOY40_RS08865 1821168..1822136 - 969 WP_162472361.1 VirK/YbjX family protein -
GOY40_RS08870 1822293..1822946 + 654 WP_031589291.1 protein-serine/threonine phosphatase -
GOY40_RS08875 1822943..1823134 - 192 WP_002911395.1 YebW family protein -
GOY40_RS08880 1823232..1823471 - 240 WP_002911393.1 YebV family protein -
GOY40_RS08885 1823587..1825020 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T181990 NZ_CP065034:1820443-1820545 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT181990 NZ_CP065034:c1820552-1820407 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References