Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) chpSB/PRK09812-ChpS
Location 4540785..4541377 Replicon chromosome
Accession NZ_CP065032
Organism Serratia sp. CMO1

Toxin (Protein)


Gene name chpB Uniprot ID -
Locus tag IT763_RS21685 Protein ID WP_049300714.1
Coordinates 4541027..4541377 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name chpS Uniprot ID -
Locus tag IT763_RS21680 Protein ID WP_049300713.1
Coordinates 4540785..4541033 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IT763_RS21660 4536605..4536943 + 339 WP_016930352.1 PTS lactose/cellobiose transporter subunit IIA -
IT763_RS21665 4536940..4538247 + 1308 WP_151254276.1 6-phospho-beta-glucosidase -
IT763_RS21670 4538318..4539298 + 981 WP_016930354.1 LacI family transcriptional regulator -
IT763_RS21675 4539490..4540674 + 1185 WP_206194995.1 MFS transporter TsgA -
IT763_RS21680 4540785..4541033 + 249 WP_049300713.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
IT763_RS21685 4541027..4541377 + 351 WP_049300714.1 type II toxin-antitoxin system ChpB family toxin Toxin
IT763_RS21690 4541374..4542657 - 1284 WP_060441380.1 cytosine deaminase -
IT763_RS21695 4542946..4545495 + 2550 WP_206194996.1 nitrite reductase large subunit NirB -
IT763_RS21700 4545492..4545818 + 327 WP_143778634.1 nitrite reductase small subunit NirD -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(8-114)

Antitoxin

Antitoxin PemI-like

(1-82)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 12404.41 Da        Isoelectric Point: 11.5657

>T181986 WP_049300714.1 NZ_CP065032:4541027-4541377 [Serratia sp. CMO1]
MVKRPVFQRGDLIRVSLNPVVGREQQGDFRPALVLSPREFNALGMVLVAPISQGANFARTAGFTVSLSGSGTATQGVILI
NQVRMMDLAGRSAQFIERAPGEVIADALARLQAIID

Download         Length: 351 bp

>T181986 NZ_CP086253:c4256861-4255974 [Pectobacterium aquaticum]
ATGCTGAAGCAACAAATTCGCCAAATTGTCCAGTCAAACCCTGACTATGCCGCAGTGACACCCGTCATAGAAAAAGAGAT
CTTGCATCATGACATTATGGATGTGCTGATCAAACAGGGCGTCATGCAGCGGTTAACGTTTATTGGCGGCACCTCATTAC
GAATGTGTTACAACAGCAGCAGGCTATCAGAAGATCTTGATTTCAATGGTGGTCATGATTTCCAGCCCTCAGCGTTTGAG
GGGCTGGAGTCCGAAATCCAAACCTATATTCAGAACAAGTATGAAACCGAAGTTTGGGTAAACAAACCTTCTGGCGAGCA
GCAAGGGGATACTGTTTCTTGGAAAATTAGTATCGTAAAAGAAGCTAATCGTCCTGATTTGCCACGGCAAAAAATGCATA
TTGACGTCTGTGCTATTCCGTCATTTGATATTGAAAAACGCCCACTAATCAATCATTACAACATCGTTGTACCGACTGAA
GGGATCTTGGTTCCGGTACAGTCGTTACAAGAAACATTGGCCGATAAGTTGATCGCGTTAGCGTATCGGGCAAGACGTAT
TAAACCTCGTGATATCTGGGATATTGTTTGGATTAAGCAGCGCGGTATTGATTTATCCAAGACACTGGTTGAAAAGAAGC
TCACCGCCAGACAGAAGCAAACAGAAGACTTTCGACAGGCGCTGTCTATTCAGTTAGCCAAGCTAATGTCGGAAGATGAA
GTCCGTGACGACTTCAATATGGAAATGAGCCGTTTTATCTCTAAGCAAATTAAAGAGAGAACCCTCGATAACCCTGCATA
TTGGGCTTATGTTCAGGGCGAGGTACATGCCATCGCGTCTGAGTTACTGAATGACGGAACACCAAAAAATCCATTTGATA
TGGGTTAG

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9069.53 Da        Isoelectric Point: 4.5026

>AT181986 WP_049300713.1 NZ_CP065032:4540785-4541033 [Serratia sp. CMO1]
MKVFIKKWGNSAGMLVPSALMNELELQVGQEMDMQVIDGALVIKPVKKRYSLQQLLDGCDGEAPAAADDNWEHMPPAGKE
VW

Download         Length: 249 bp

>AT181986 NZ_CP086253:c4257414-4256890 [Pectobacterium aquaticum]
ATGGCTAAATCTGATGAGCTATTAAACGCGTTGGCCAAAGCAGTGAACGCCGGCGGCGGCATTCACAGTGTAACAGAGCT
GGCTTTTATGCAGGGTGTGCCTTGTGACTCAGCCTTTAGAAAATTCCTGGCAGATTGCGTAAAGAAGGGGTTGCTAAGAC
GAGTGGTGAAAGGCTTCTATGAAAGTGTTATTACACCACCTGAGCCTGAGACTGCCATTTATAAAATCATCAAAAAGTTG
CGCAGCGGCGTATTGAGCTACATCAGCTTAGAAAGTCAGCTCAGTCATACCGGTGATATTTCACAAGTTGTGATGGGTAG
AGTCACTGTGGTGACTAAAGGTCGAAGTGGTTGTTTTGATACGCCTTATGGCGTGATCGAGTTTACCCATACTAAAAAGC
CAGTCGAGCAAATTGCACCTAATTTGTATTATGACCCCGACATCAAAATGTATCGCGCATACAAGGAACAAGCGATTGCA
GATCTAAAACACTGCCAGCGCAATCTACATATGTTGGAGAGCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References