Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 3635652..3636308 Replicon chromosome
Accession NZ_CP065032
Organism Serratia sp. CMO1

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag IT763_RS17365 Protein ID WP_016926704.1
Coordinates 3635652..3636041 (-) Length 130 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID A0A8G2LCA8
Locus tag IT763_RS17370 Protein ID WP_004941563.1
Coordinates 3636045..3636308 (-) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IT763_RS17350 3632119..3633549 + 1431 WP_016926706.1 multidrug transporter subunit MdtD -
IT763_RS17355 3633546..3634928 + 1383 WP_016926705.1 two-component system sensor histidine kinase BaeS -
IT763_RS17360 3634928..3635644 + 717 WP_004941568.1 two-component system response regulator BaeR -
IT763_RS17365 3635652..3636041 - 390 WP_016926704.1 type II toxin-antitoxin system VapC family toxin Toxin
IT763_RS17370 3636045..3636308 - 264 WP_004941563.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
IT763_RS17375 3636646..3636984 + 339 WP_004941561.1 YegP family protein -
IT763_RS17380 3637163..3638515 + 1353 WP_049299962.1 tRNA 5-hydroxyuridine modification protein YegQ -
IT763_RS17385 3638983..3639888 + 906 WP_143779312.1 lipid kinase YegS -
IT763_RS17390 3640057..3641271 + 1215 WP_016926700.1 D-galactonate dehydratase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-119)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 14342.61 Da        Isoelectric Point: 7.8794

>T181983 WP_016926704.1 NZ_CP065032:c3636041-3635652 [Serratia sp. CMO1]
MYMFDTNTVSHLFRQHPQVLNVMEKLPPSAVCISSVTEAELLYGVAKRRNKALQSMVEAFLAAVTVYAWDSEAARCYGEM
RATMERKGKIMGAMDQLIAAHAQSRGATLVTNDRAFAMVPGLAVEDWTR

Download         Length: 390 bp

>T181983 NZ_CP086253:c3324238-3323321 [Pectobacterium aquaticum]
ATGGATAAGCAATCACCTTATTATCGGCAAGTTGCGTTGCTGCTCAGCGCATTACCTGTAGTGGCATCAGAGCGATGCTT
TGCACTAAAAGGAGGAACGGCAATAAACTTGTTTGTCCGTGATTTTCCACGTTTGTCGGTTGATATCGATTTGGCTTACA
TTCCGCTGGAAAGCAGAGATGTGGCATTGCCAAATGTTCGGGCTGCTTTGACGCGGATTGCTGAAATACTGCAACAACAG
GTTGGTATTTCGGCGGTACTACAAACGAATAATCCTGATGAAATGCGCATTGTGGTTTCTTCTCCGGAGGCGCAGATAAA
GATAGAAGTTTCGCCTGTTGCACGAGGCACACTGTATCCTCCAGAAGAACGTGACGTTGTTGAAGCGGTAGAAGACGAAT
TCGGTTTTGCTACTATTCCGGTTGTATCGCTTGCCGATCTCTATGGTGGAAAGCTTTGCGCTGCATTGGATAGGCAACAT
CCCCGTGATTTTTATGACGTCAAAATGCTACTCGAAACGCAAGGTATTGATCGCCACATTTTTAATGGTTTCATCACCTA
TCTACTGGGACATAAGCGCCCGTTATCAGAAATCTTAGATCCTCATTGGAAAGATATTTCTTTGCCATACGCAAATGAAT
TTAACGGAATGACATTCGATACGGTCTCTCTGGAAGAACTCAATGCGATACCCAACTTGATGGTCACCGCCCTCAAAGCA
CAATTCACGCAGCAGGATTATGACTTTTTGATGTCTTTCAAAAGTGGTCAACCGGACTGGAGTCTAGCGCCTGAAGATCA
GATTCAGCATCTGCCCGCGGTTAAGTGGAAGTTGCAAAATATTGTGCGCATACCAAAAGATAAGCATATTCAGGCGTTGG
CGAAGCTTGAGACGGTTCTCGCTGAGTGGATAAGGTAG

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 10062.31 Da        Isoelectric Point: 4.6702

>AT181983 WP_004941563.1 NZ_CP065032:c3636308-3636045 [Serratia sp. CMO1]
MERIAKLFKNGRNQAVRLPVEFEFDTDRVYIRRDREGNVILSKYPAKPDSWAPLLSIIAQTPVPQEFLGAEDRQQGVADR
DPFSEEE

Download         Length: 264 bp

>AT181983 NZ_CP086253:c3325004-3324231 [Pectobacterium aquaticum]
ATGTCATCAAAACTAAACTGGCTTTTGCAGAACACTGCACCGGGCTCTTTGGTATTACAGTCTTGGCTGACAAAAAACGG
TATTAGCCCTTCTTTAGCCAATAAGTATATGCACAGCGACTGGCTGCAAAAGCTACGTGCTGGGGTATACGTGCGGAGTG
GGCGTGAAGCGCAGTGGAGTGATGCCGTTCTATGCTTGCAAAATCAGCTTGGGATTTCTGTACATCTGGCGGGGCTTACT
AGCCTGACTTATCAGGGGCGATCTCATTATCTTCACTTAAAGCATCAGGCCATTTGGCTCTGTGTAGAAGATAAAGCTTC
TCTGCCAAAGTGGTTCAAAGAATTCCCCAATGTCGAGTGGCTTTTACTTTCTAATCAGAAGCTCAATATGAATGATGAAA
AGTATCTGACAGAGATCGAAATTAAAGGGGAGCTGTTGAAAGCGAGTGTGCCGGAACTAGCGGCTTACGAGATTGCTAAT
GCAGTCCCTGGTTCGCTTTCATTTGAGCACGCTGCGGAGTTGTTTCAGGGGCTGGTAAACCTGAGTCCGCGTAAAGTTGA
AGTATTATTGCAATCTAGTCGAGCAGTGCAAACTAACCGCCTTTATCTGTTTCTAGCCGATCACTATGCTCATGCATGGG
GTAAGCGAATAGATAAAGCCAACGTTGAGTTAGGGGCCGGAAAACGGCAGATCGTATCGGGTGGCAAACTGGATCAAAAA
TATCAGATCACCGTTCCAGAGCGTTTTGTTAGCAAAGGGATCTCACATGGATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References