181966

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) stbDE/ParE-DnaT
Location 4590815..4591346 Replicon chromosome
Accession NZ_CP065031
Organism Pectobacterium brasiliense strain F126

Toxin (Protein)


Gene name stbE Uniprot ID A0A086EVU3
Locus tag F126LOC_RS20120 Protein ID WP_039282785.1
Coordinates 4590815..4591102 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name stbD Uniprot ID A0A1V2R9J2
Locus tag F126LOC_RS20125 Protein ID WP_039282788.1
Coordinates 4591092..4591346 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
F126LOC_RS20100 4586256..4587647 + 1392 WP_039282780.1 outer membrane channel protein TolC -
F126LOC_RS20105 4587918..4588592 + 675 WP_010280216.1 DUF1190 family protein -
F126LOC_RS20110 4588604..4589764 + 1161 WP_039462681.1 glutathionylspermidine synthase family protein -
F126LOC_RS20115 4589832..4590617 - 786 WP_119871053.1 4,5-DOPA dioxygenase extradiol -
F126LOC_RS20120 4590815..4591102 - 288 WP_039282785.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
F126LOC_RS20125 4591092..4591346 - 255 WP_039282788.1 plasmid stabilization protein Antitoxin
F126LOC_RS20135 4592171..4593058 - 888 WP_039556326.1 16S rRNA (cytidine(1402)-2'-O)-methyltransferase -
F126LOC_RS20140 4593120..4595138 + 2019 WP_039282794.1 penicillin-binding protein activator -
F126LOC_RS20145 4595096..4595491 + 396 WP_072036118.1 YraN family protein -
F126LOC_RS20150 4595555..4596145 + 591 WP_005975525.1 DnaA initiator-associating protein DiaA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-86)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11011.96 Da        Isoelectric Point: 10.7694

>T181966 WP_039282785.1 NZ_CP065031:c4591102-4590815 [Pectobacterium brasiliense]
MTYKLKFVPSAMKEWKKLGHPVREQFKKKLVERLENPRVPSAQLHGRKDQYKIKLKSAGYRLVYLVQDETITVMVMGVGK
REGSQIYSDTKGRSA

Download         Length: 288 bp

>T181966 NZ_CP086224:c14266-13916 [Escherichia coli]
ATGTGGGTCATCGAGACAACCGACACCTTTGATGAGTGGTTCGATGCTCTGGATGATACCGATAGAGCAAACGTGCTGGC
TTCGATGATGGTGCTGCGAGATAGAGGCCCCATGCTGTCGAGGCCATACGCGGATACTGTTAACGGTTCATCCTACAGCA
ACATGAAAGAGCTTCGGGTCCAAAGCAAAGGAGATCCTATCAGAGCGTTCTTTGCGTTCGATCCAAAGCGTAAGGGGATT
CTTCTCTGCGCCGGTAACAAGACCGGGGACGAGAAAAGGTTTTATGAAGTAATGATCCCAATTGCAGACCGTGAGTTTGC
GGCGCACTTGGATAAATTGAAGAAGGAGTGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9208.38 Da        Isoelectric Point: 3.7947

>AT181966 WP_039282788.1 NZ_CP065031:c4591346-4591092 [Pectobacterium brasiliense]
MAFNILTNTAASITELKRDPMGTVRAAEGETIAILNRNEPAFYCVPPAVFAYLMELAEDAELGRTVDDRMSELADAEEIS
LDDL

Download         Length: 255 bp

>AT181966 NZ_CP086224:c13911-13609 [Escherichia coli]
ATGGCAAGAACTCTTGACCAAATGCTGGCAACAGAAAAGCCTGAGGTTGTTGCCAAAGCACAGAAAGCGGCCACTGAGAT
GTTACTGAACATCCACTTGGCAGAGCTTCGTGATCGCATGAACCTTACCCAGGGGGAAATTGCTGCATCTCTGGGTGTGA
GACAGCCGACAGTCTCCGAGATGGAAAAACCTGGACGAGATCTCAAGCTGTCGTCCATTAAGCGGTACGTTGAGGCCTCC
GGTGGCAAGCTACGCCTCGATGTTGAACTTCCGGACGGCACCCACTACGGCTTTGCCGTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A086EVU3

Antitoxin

Source ID Structure
AlphaFold DB A0A1V2R9J2

References