Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 4496585..4497112 Replicon chromosome
Accession NZ_CP065031
Organism Pectobacterium brasiliense strain F126

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag F126LOC_RS19695 Protein ID WP_119871082.1
Coordinates 4496585..4496860 (-) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag F126LOC_RS19700 Protein ID WP_119871081.1
Coordinates 4496864..4497112 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
F126LOC_RS19670 4491743..4492975 + 1233 WP_119871085.1 FtsX-like permease family protein -
F126LOC_RS19675 4492965..4494500 + 1536 WP_119871084.1 SUMF1/EgtB/PvdO family nonheme iron enzyme -
F126LOC_RS19680 4494523..4495227 + 705 WP_014913963.1 hypothetical protein -
F126LOC_RS19685 4495238..4495720 + 483 WP_014913962.1 hypothetical protein -
F126LOC_RS19690 4496025..4496537 - 513 WP_119871083.1 AAA family ATPase -
F126LOC_RS19695 4496585..4496860 - 276 WP_119871082.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
F126LOC_RS19700 4496864..4497112 - 249 WP_119871081.1 ribbon-helix-helix domain-containing protein Antitoxin
F126LOC_RS19705 4497222..4497407 - 186 Protein_3856 DUF4942 domain-containing protein -
F126LOC_RS19710 4497426..4500674 - 3249 WP_119871080.1 type I restriction endonuclease subunit R -
F126LOC_RS19715 4500671..4501657 - 987 WP_119871220.1 restriction endonuclease subunit S -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 4496025..4511279 15254


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(9-43)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 11046.26 Da        Isoelectric Point: 5.1631

>T181965 WP_119871082.1 NZ_CP065031:c4496860-4496585 [Pectobacterium brasiliense]
MEIRWTQKAQDDLERIYGFASQYSRQHADEVLDRLIIGTTGLADYPRIGVSQTRYEPREVRKILFDDYEVHYEIQHDTSY
IVDLWHKREDR

Download         Length: 276 bp

>T181965 NZ_CP086223:19759-20139 [Escherichia coli]
ATGAGGCATATATCACCGGAAGAACTTATTGCGCTTCATGATGCGAATATAAGCCGCTACGGCGGCCTGCCGGGAATGTC
TGATCCGGGTAGGGCAGAGGCCATTATCGGGAGAGTTCAGGCCAGAGTTGCCTACGAAGAGATCACCGACCTTTTCGAAG
TCTCCGCCACCTACCTGGTGGCTACAGCGAGAGGGCATATATTCAATGATGCCAATAAGCGTACCGCGCTAAACAGTGCG
CTGTTATTTCTACGCCGTAACGGGGTGCAGGTATTTGATTCACCTGAACTGGCAGACCTTACTGTAGGCGCTGCGACTGG
CGAGATATCTGTATCTTCTGTCGCCGACACGTTACGTAGATTGTATGGTCCTGCGGAGTAG

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9090.52 Da        Isoelectric Point: 10.0121

>AT181965 WP_119871081.1 NZ_CP065031:c4497112-4496864 [Pectobacterium brasiliense]
MGQPAKQTISAQIPAELAAAVERLAIELDRSKSWVIKEALTAMIEERERRHQRILKGLADVDAGRVVSHADVIDFANKLK
KS

Download         Length: 249 bp

>AT181965 NZ_CP086223:19538-19759 [Escherichia coli]
ATGCGATCCATTAACTTCCGTACCGCGCGTGGCAACCTTTCTGAAGTGCTCAACAATGTTGAAGCCGGGGAAGAGGTTGA
AATCACCCGCAGAGGCCGTGAGCCAGCAGTAATTGTCAGCAAGGCTACTTTCGAAGCCTACAAAAAAGCGGCGCTGGATG
CTGAATTTGCATCCCTGTTTGACACCCTGGACTCCACCAACAAGGAACTGGTTAACCGATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References