Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/ParE-RHH
Location 4441558..4442141 Replicon chromosome
Accession NZ_CP065031
Organism Pectobacterium brasiliense strain F126

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag F126LOC_RS19475 Protein ID WP_119871112.1
Coordinates 4441558..4441863 (-) Length 102 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag F126LOC_RS19480 Protein ID WP_119871111.1
Coordinates 4441851..4442141 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
F126LOC_RS19460 4437974..4438933 + 960 WP_039279295.1 ABC transporter permease -
F126LOC_RS19465 4438926..4439792 + 867 WP_010285293.1 ABC transporter permease -
F126LOC_RS19470 4439789..4441498 + 1710 WP_119871113.1 ABC transporter ATP-binding protein -
F126LOC_RS19475 4441558..4441863 - 306 WP_119871112.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
F126LOC_RS19480 4441851..4442141 - 291 WP_119871111.1 ribbon-helix-helix protein, CopG family Antitoxin
F126LOC_RS19485 4442203..4443057 - 855 WP_119871110.1 helix-turn-helix domain-containing protein -
F126LOC_RS19490 4443082..4443921 - 840 WP_014913998.1 HTH-type transcriptional activator RhaS -
F126LOC_RS19495 4444258..4445748 + 1491 WP_119871109.1 rhamnulokinase -
F126LOC_RS19500 4445745..4447007 + 1263 WP_039282588.1 L-rhamnose isomerase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-96)

Antitoxin

Ribbon-helix-helix protein, CopG

(9-46)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11602.42 Da        Isoelectric Point: 9.4590

>T181964 WP_119871112.1 NZ_CP065031:c4441863-4441558 [Pectobacterium brasiliense]
MPQVIVSERARRDLQRLQDFLKNKNALAAKKAAEVLIRGIRQLEALPNIGRPVEHLPLEYQELVIEFGSSGYVVLYRHDE
LTDRVVILTVKHQKEAGYQNP

Download         Length: 306 bp

>T181964 NZ_CP086221:88062-89387 [Escherichia coli]
ATGAGCCGGAAACAGCAACGTCTGGTAATTTGGATGAACGGCATCAAAGTCGGGTACTGGGAAAAAAGCAAAGGGGTAGA
CAGCTTAGAATACCTTCCTGAATGGGTTGCTGACGAACAGGGAAGGCCGCTGTCATTGTCCCTTCCTTTTACTCCCGGGA
ACCAGGTCTGGCGTGGAAATGTGGTACGTGACTATTTTGATAATTTACTGCCGGACAGCGAAGGCATACGCAGACGTCTG
GCAATGCGTTACAAGGCCGATAGCCTGGAGCCTTTTGATCTGCTGACGGAGCTGGGAAAAGACTGCGTGGGCGCGATACA
GCTGCTTCATGACGGAGATGAACCCACTGATTTATATTCCGTGAAGTATCACCCGCTTACTGAATCAGAAATTGCGGCAA
CTTTGCGTAATACCACGGAGACATTGCTACCGGGCAGGCCAGAAGATAACGACGACTTACGTTTATCTATTGCCGGTGCT
CAGGAGAAAACAGCCCTACTGTGGCATGAAGATCGGTGGTGTATGCCGGAGGGTAATACACCAACGACGCATATATTCAA
GCTACCGCTCGGACTTGTGGGGAACATGAAAGCCGACATGAGCTCGTCGGTTGAAAATGAATGGCTCTGCTCGGTACTTC
TCGGCCAGTACGGGCTCCCCGTGGCAAGAACGCAGATTGCTCACTTTGAAGATCAGAAAGCGCTGGTGGTAGAACGTTTT
GACCGAAAATGGTCAGGAGACGGACAATGGATCATTCGTTTACCCCAGGAGGATATGTGTCAGGCCCTGGGCGTTTCGCC
ATTACGAAAATATCAGGCGGACGGCGGGCCAGGTATATCGGAAATTATGGAGGTTCTGAGTAATTCAGACCGTGCTGAGC
GTGACAAAGCGCAGTTTTTTATGACGCAGATAATTTTCTGGATGATGGCCGCAACAGATGGCCACGCTAAAAATTTCAGT
ATTTCTATTGGGCCACAGGGACGTTATCACCTTACACCAAACTATGATGTGTTGTCGGCATGGCCGGTGATCGGTCATGG
GAACAATCAGATATCCTGGCAGAAGTGCAAACTGGCGATGGCCGTACGTGGCAGTAGCAACTATTACCAGATATATCGAA
TACAACGACGCCACTGGATCAGGCATGGTGAGATAACCGGCCTGAGTAAACAGCAGACAGAGGCGATGATAGAGGAAATC
ATCGCCAGAACCCCGGGTGTCATTGAACGTGTTAGCGGGCTTCTTCCGGACCAGTTCCCCCAGCAGCTTGCGGAAAGTAT
TTTTGATGGAATGAGGCAGCAATGCAGGCGCCTGGCTGAGAAATGA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 11100.17 Da        Isoelectric Point: 4.7845

>AT181964 WP_119871111.1 NZ_CP065031:c4442141-4441851 [Pectobacterium brasiliense]
MADTPRQTTTLRIDQDIKERLKTLADDRHSSAHALMLEAITEYVEREEKRSQYRKEALAAWEEYQSTGEHITADETVTWL
ESWGSGHEQDAPACHK

Download         Length: 291 bp

>AT181964 NZ_CP086221:87764-88057 [Escherichia coli]
ATCAATAATGATTACCCGTTAAACACGCTCAACCAGCTGCGTCCCTTGCTCATTGGTTTTCGCAAGGCGAATGGCCTGAC
GCAAAAAGACCTGTCCGAAAGGTTAGGCGTCACTCAACAGACATACTCACGTCTGGAAGCCAACCCTGCCAGTGCGAGCA
TTGAACGGCTATTCAAGGTGTTTTCCATCCTGGGCGTAAAAATCAGCTTCTCCTCGGCAACCACCTCTTCAGAGAGGAAG
CAGACGGAAGAAATGCTTAAATCAAACTCACCTGCACGACAGGAGGATTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References