Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PP_4151-4152/excise(antitoxin)
Location 3718410..3719446 Replicon chromosome
Accession NZ_CP065031
Organism Pectobacterium brasiliense strain F126

Toxin (Protein)


Gene name PP_4152 Uniprot ID -
Locus tag F126LOC_RS16100 Protein ID WP_119871526.1
Coordinates 3718410..3718985 (-) Length 192 a.a.

Antitoxin (Protein)


Gene name PP_4151 Uniprot ID -
Locus tag F126LOC_RS16105 Protein ID WP_119871525.1
Coordinates 3718985..3719446 (-) Length 154 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
F126LOC_RS16080 3716273..3716668 - 396 WP_014914413.1 prepilin-type N-terminal cleavage/methylation domain-containing protein -
F126LOC_RS16085 3716655..3717071 - 417 WP_119871529.1 YgdB family protein -
F126LOC_RS16090 3717107..3717733 - 627 WP_119871528.1 prepilin peptidase-dependent protein -
F126LOC_RS16095 3717727..3718230 - 504 WP_119871527.1 prepilin peptidase-dependent protein -
F126LOC_RS16100 3718410..3718985 - 576 WP_119871526.1 PIN domain-containing protein Toxin
F126LOC_RS16105 3718985..3719446 - 462 WP_119871525.1 helix-turn-helix domain-containing protein Antitoxin
F126LOC_RS16110 3719669..3720463 - 795 WP_039312476.1 thymidylate synthase -
F126LOC_RS16115 3720500..3721366 - 867 WP_010286783.1 prolipoprotein diacylglyceryl transferase -
F126LOC_RS16120 3721593..3723839 - 2247 WP_039283946.1 phosphoenolpyruvate--protein phosphotransferase -
F126LOC_RS16125 3723852..3724385 - 534 WP_010282870.1 RNA pyrophosphohydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(8-115)

Antitoxin

Helix-turn-helix domain, group 17

(84-132)


Sequences

Toxin        


Download         Length: 192 a.a.        Molecular weight: 21493.91 Da        Isoelectric Point: 4.7230

>T181960 WP_119871526.1 NZ_CP065031:c3718985-3718410 [Pectobacterium brasiliense]
MNHSPYPVVLDACVIYPSLLRDLLMHLGLTGLYQPKWTVLIQEEWQRNLLLNNADVTMDKLRNIEHLMNKALPDANVTGF
EQLIPALVLPDADDRHVLAAAIRANAEVIVTANLKDFPATSLSEFGVEAMHPDEFIADLFDLNSALVLKAVRTSRTAFRK
PPFDVDEYLDCLLRQGLPMTVKELDAYRALI

Download         Length: 576 bp

>T181960 NZ_CP086220:4067006-4067317 [Escherichia coli]
ATGCTCTTCATCGAAACGGAAATTTTTACTGAAGATGTTCAAAAACTGCTGACCGACGATGAATTCAGTCGTTTTCAGTT
TTTCCTGGCCTTGAATCCTGACTATGGTGAGGTAATACCTGAAACTGGTGGGTTAAGAAAGGTTCGATGGGTTTCAGGAG
GAAAGGGGAAACGTGCTGGTGTCAGGGTTATTTACTTTCATCAGGTTAAACATTATGAGATCAGATTACTGCTTATTTAT
CGTAAGGGTATTAAAGATGATCTGTCTCCCCAGGAAAAAGCAATGCTCCGGTTGTTAAATACGAGGTGGTAA

Antitoxin


Download         Length: 154 a.a.        Molecular weight: 17277.78 Da        Isoelectric Point: 6.2253

>AT181960 WP_119871525.1 NZ_CP065031:c3719446-3718985 [Pectobacterium brasiliense]
MKNTPLNSLSLPAPKEMEAAIRGQRQLATYLSTKLETQEISIQDAHDIAHRIELPTSALTLLMSILGELAAGNAVQIVPV
QAELTTQEAANILNVSRPHMVKLLEEGHLPFHKTGRHRRVLFADLMQYKEQRENESMQAMQELTDRSQEFGFY

Download         Length: 462 bp

>AT181960 NZ_CP086220:4067318-4067608 [Escherichia coli]
ATGGATAAGGCACTTTTTGAGCGGTTGACTCACAGCATGGCCCAGATGAATGAAATTATTGAAGGAACGCGACAGCCTTC
GCGGACTTTTGAAGTTGATGCTATGAAAATCAAAGAAATACGCCGCGCTTCAGGGTTGTCACAATCTAAATTTGCCGATC
TTATTTCTGTAAGCGTAGACACGTTGCGTAACTGGGAGCAGGGGCGACGTTCACCGACCGGGCCAGCAAAGGCTTTGCTG
CGAGCGATTGCCAATGATCCGCAACATGTGCTGCAAGCACTTAACCGTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References