Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | ataRT/DUF1778(antitoxin) |
Location | 145754..146505 | Replicon | chromosome |
Accession | NZ_CP065031 | ||
Organism | Pectobacterium brasiliense strain F126 |
Toxin (Protein)
Gene name | ataT | Uniprot ID | A0A433N1V3 |
Locus tag | F126LOC_RS00610 | Protein ID | WP_010281603.1 |
Coordinates | 146023..146505 (+) | Length | 161 a.a. |
Antitoxin (Protein)
Gene name | ataR | Uniprot ID | A0A0M2EWB4 |
Locus tag | F126LOC_RS00605 | Protein ID | WP_039317395.1 |
Coordinates | 145754..146032 (+) | Length | 93 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
F126LOC_RS00575 | 140912..141826 | - | 915 | WP_119870802.1 | NAD(P)-dependent oxidoreductase | - |
F126LOC_RS00580 | 142164..142922 | + | 759 | WP_119870824.1 | DeoR/GlpR family DNA-binding transcription regulator | - |
F126LOC_RS00585 | 143143..143541 | + | 399 | WP_127110965.1 | hypothetical protein | - |
F126LOC_RS00590 | 143538..144386 | - | 849 | WP_119870804.1 | DUF4225 domain-containing protein | - |
F126LOC_RS00595 | 144388..144867 | - | 480 | WP_039511462.1 | Hcp family type VI secretion system effector | - |
F126LOC_RS00600 | 145228..145644 | + | 417 | WP_119870805.1 | hypothetical protein | - |
F126LOC_RS00605 | 145754..146032 | + | 279 | WP_039317395.1 | DUF1778 domain-containing protein | Antitoxin |
F126LOC_RS00610 | 146023..146505 | + | 483 | WP_010281603.1 | GNAT family N-acetyltransferase | Toxin |
F126LOC_RS00615 | 146638..147972 | + | 1335 | WP_119870806.1 | sn-glycerol-3-phosphate ABC transporter substrate-binding protein UgpB | - |
F126LOC_RS00620 | 148045..148932 | + | 888 | WP_010281599.1 | sn-glycerol-3-phosphate ABC transporter permease UgpA | - |
F126LOC_RS00625 | 148958..149803 | + | 846 | WP_010281598.1 | sn-glycerol-3-phosphate ABC transporter permease UgpE | - |
F126LOC_RS00630 | 149829..150902 | + | 1074 | WP_119870807.1 | sn-glycerol-3-phosphate import ATP-binding protein UgpC | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 161 a.a. Molecular weight: 17509.30 Da Isoelectric Point: 9.0439
>T181953 WP_010281603.1 NZ_CP065031:146023-146505 [Pectobacterium brasiliense]
MGITAPEPLSSSHNLAEFCSQEPSLNEWLKKKALKNHSAGISRVYVICAEGTHQVIGYYCLSTGSVQRNTAPGAYRRNAP
ESLPVIVLGRLAIDQAYSGKGLGVALLKDAIFRTENIALQVGVRALVVHALDENVRNFYLKFAFDPSPVQPLMLLYPIKI
MGITAPEPLSSSHNLAEFCSQEPSLNEWLKKKALKNHSAGISRVYVICAEGTHQVIGYYCLSTGSVQRNTAPGAYRRNAP
ESLPVIVLGRLAIDQAYSGKGLGVALLKDAIFRTENIALQVGVRALVVHALDENVRNFYLKFAFDPSPVQPLMLLYPIKI
Download Length: 483 bp
>T181953 NZ_CP086220:c2459486-2459088 [Escherichia coli]
ATGCTGAAATTCATGCTGGATACCAATATCTGTATTTTCACTATTAAGAATAAACCAGTACATGTCAGAGAGCGGTTTAA
CCTGAATTCTGGCCGGATGTGTATAAGTTCTGTAACATTGATGGAGCTTATCTATGGGGCAGAAAAAAGTCAGATGCCAG
AACGCAATTTGGCGGTTATTGAAGGTTTCGTATCTCGTTTGGTAGTGCTTGATTATGATAGTGCTGCTGCGACGCATACC
GGGCAAATCAGGGCCGAGCTTGCCCGGCAGGGAAGGCCTGTTGGACCTTTTGACCAGATGATAGCGGGACATGCTCGCAG
TCGCGGTTTGATTGTGGTTACCAACAATACCCGAGAGTTTGAGCGAGTGGCGGGAATCAGACTAGAAGACTGGAGCTAA
ATGCTGAAATTCATGCTGGATACCAATATCTGTATTTTCACTATTAAGAATAAACCAGTACATGTCAGAGAGCGGTTTAA
CCTGAATTCTGGCCGGATGTGTATAAGTTCTGTAACATTGATGGAGCTTATCTATGGGGCAGAAAAAAGTCAGATGCCAG
AACGCAATTTGGCGGTTATTGAAGGTTTCGTATCTCGTTTGGTAGTGCTTGATTATGATAGTGCTGCTGCGACGCATACC
GGGCAAATCAGGGCCGAGCTTGCCCGGCAGGGAAGGCCTGTTGGACCTTTTGACCAGATGATAGCGGGACATGCTCGCAG
TCGCGGTTTGATTGTGGTTACCAACAATACCCGAGAGTTTGAGCGAGTGGCGGGAATCAGACTAGAAGACTGGAGCTAA
Antitoxin
Download Length: 93 a.a. Molecular weight: 10667.12 Da Isoelectric Point: 4.3611
>AT181953 WP_039317395.1 NZ_CP065031:145754-146032 [Pectobacterium brasiliense]
MKPETKEAPINIRAKASQRDLIDMAANLVSKSRTDFMLEAACREAQDILLDQRLFILDNEQFDEFLAELDAPITEERQAR
INDLMSRKSPWE
MKPETKEAPINIRAKASQRDLIDMAANLVSKSRTDFMLEAACREAQDILLDQRLFILDNEQFDEFLAELDAPITEERQAR
INDLMSRKSPWE
Download Length: 279 bp
>AT181953 NZ_CP086220:c2459713-2459486 [Escherichia coli]
ATGGAAACTACTGTATTTTTAAGTAATCGCAGTCAGGCCGTCAGATTACCGAAAGCGGTCGCTCTGCCAGAAGACGTTAA
GAAAGTAGAAATTATTGCGATTGGTCGTACAAGAATCATCACTCCCGCCGGTGAGTCCTGGGACAGTTGGTTTGATGGCG
AAAATGTGAGTGCGGATTTTATGGATATCCGTGATCAACCCGCAATGCAGGAAAGGGAATCATTTTGA
ATGGAAACTACTGTATTTTTAAGTAATCGCAGTCAGGCCGTCAGATTACCGAAAGCGGTCGCTCTGCCAGAAGACGTTAA
GAAAGTAGAAATTATTGCGATTGGTCGTACAAGAATCATCACTCCCGCCGGTGAGTCCTGGGACAGTTGGTTTGATGGCG
AAAATGTGAGTGCGGATTTTATGGATATCCGTGATCAACCCGCAATGCAGGAAAGGGAATCATTTTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A433N1V3 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A0M2EWB4 |