Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) sdenTA/AbiEii(toxin)
Location 4605409..4606850 Replicon chromosome
Accession NZ_CP065030
Organism Pectobacterium versatile strain F131

Toxin (Protein)


Gene name sdenT Uniprot ID A0A855MBQ9
Locus tag F131LOC_RS20530 Protein ID WP_039296419.1
Coordinates 4605409..4606296 (-) Length 296 a.a.

Antitoxin (Protein)


Gene name sdenA Uniprot ID A0A855MAW0
Locus tag F131LOC_RS20535 Protein ID WP_039296424.1
Coordinates 4606326..4606850 (-) Length 175 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
F131LOC_RS20505 4600569..4601516 + 948 WP_103972359.1 isoaspartyl peptidase/L-asparaginase -
F131LOC_RS20510 4601721..4602629 + 909 WP_039542502.1 LysR family transcriptional regulator -
F131LOC_RS20515 4602728..4603591 + 864 WP_010300687.1 YicC family protein -
F131LOC_RS20520 4603785..4604173 + 389 Protein_4001 DUF4102 domain-containing protein -
F131LOC_RS20525 4604363..4605187 + 825 WP_039296417.1 DNA damage-inducible protein D -
F131LOC_RS20530 4605409..4606296 - 888 WP_039296419.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
F131LOC_RS20535 4606326..4606850 - 525 WP_039296424.1 hypothetical protein Antitoxin
F131LOC_RS20540 4607169..4609658 - 2490 WP_051985946.1 restriction endonuclease-like protein -
F131LOC_RS20545 4609677..4610927 - 1251 WP_051985948.1 AAA family ATPase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 4604363..4615236 10873


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(39-265)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 296 a.a.        Molecular weight: 34019.93 Da        Isoelectric Point: 5.9876

>T181951 WP_039296419.1 NZ_CP065030:c4606296-4605409 [Pectobacterium versatile]
MLKQQIRQIVQSNPDYAAVTPVIEKEILHHDIIDVLIKQGVMQRLTFIGGTSLRMCYNSSRLSEDLDFNGGHDFQPSAFE
GLESEIQTYIQNKYETEVWVNKPSGEQQGDTVSWKISIVKEANRPDLPRQKMHIDVCAIPSFDIEKRPLINHYNIVVPTE
GILVPVQSLQETLADKLIALAYRARRIKPRDIWDIVWIKQRGIDLSKTLVEKKLTARQKQTEDFRQALSIQLAKLMSEDE
VRDDFNMEMSRFIPKQIKERTLDNPEYWAYVQGEVHAIASELLNDGTPKNPFNMG

Download         Length: 888 bp

>T181951 NZ_CP086220:c1948559-1948305 [Escherichia coli]
GTGAAACTAATCTGGTCTGAGGAATCATGGGATGATTATCTGTACTGGCAGGAAACAGATAAGCGAATTGTTAAAAAGAT
CAATGAACTTATCAAAGATACCCGCAGAACGCCATTTGAAGGTAAGGGGAAGCCAGAACCCCTGAAACATAATTTGTCAG
GTTTCTGGTCCCGACGCATTACAGAGGAGCACCGTCTGGTATACGCGGTTACCGACGATTCACTGCTCATTGCAGCATGT
CGTTATCATTATTGA

Antitoxin


Download         Length: 175 a.a.        Molecular weight: 19289.42 Da        Isoelectric Point: 9.0504

>AT181951 WP_039296424.1 NZ_CP065030:c4606850-4606326 [Pectobacterium versatile]
MAKSDELLSALAKSVNAGGGIHSVTELAFMQGGPCDPAFRKFLADCVKKGLLRRVVKGFYESVITPPEPETAIYKIIKKL
RSGVLNYISLESQLSHTGDISQVVMGRVTVVTKGRSGCFDTPYGVIELTHTKKPVEQIAPNLYYDPDIKMYRAYKEQAIA
DLKHCQRNLHMLES

Download         Length: 525 bp

>AT181951 NZ_CP086220:c1948807-1948556 [Escherichia coli]
ATGCGTACAATTAGCTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTTATTACTCGTCAGAATGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCGCTGGAAGAGACGGCTTATC
TACTGCGCTCCCCCGCTAACGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGGCAAAGGAACAGAAAAGGAC
ATTATTGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A855MBQ9

Antitoxin

Source ID Structure
AlphaFold DB A0A855MAW0

References