Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | hicAB/HicA-HicB |
Location | 1221614..1222250 | Replicon | chromosome |
Accession | NZ_CP065030 | ||
Organism | Pectobacterium versatile strain F131 |
Toxin (Protein)
Gene name | hicA | Uniprot ID | - |
Locus tag | F131LOC_RS05450 | Protein ID | WP_103941744.1 |
Coordinates | 1221614..1221796 (+) | Length | 61 a.a. |
Antitoxin (Protein)
Gene name | hicB | Uniprot ID | - |
Locus tag | F131LOC_RS05455 | Protein ID | WP_103970630.1 |
Coordinates | 1221819..1222250 (+) | Length | 144 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
F131LOC_RS05425 | 1216979..1217182 | + | 204 | WP_005976130.1 | YbdD/YjiX family protein | - |
F131LOC_RS05430 | 1217199..1218185 | + | 987 | WP_103970626.1 | GTPase | - |
F131LOC_RS05435 | 1218454..1219836 | + | 1383 | WP_103970627.1 | glycoside hydrolase family 28 protein | - |
F131LOC_RS05440 | 1220070..1220549 | - | 480 | WP_103970628.1 | Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase YbaK | - |
F131LOC_RS05445 | 1220620..1221438 | - | 819 | WP_103970629.1 | TraB/GumN family protein | - |
F131LOC_RS05450 | 1221614..1221796 | + | 183 | WP_103941744.1 | type II toxin-antitoxin system HicA family toxin | Toxin |
F131LOC_RS05455 | 1221819..1222250 | + | 432 | WP_103970630.1 | type II toxin-antitoxin system HicB family antitoxin | Antitoxin |
F131LOC_RS05460 | 1222344..1225067 | - | 2724 | WP_103970631.1 | copper-exporting P-type ATPase CopA | - |
F131LOC_RS05465 | 1225183..1225590 | + | 408 | WP_103970632.1 | Cu(I)-responsive transcriptional regulator | - |
F131LOC_RS05470 | 1225626..1226081 | - | 456 | WP_103970633.1 | NfeD family protein | - |
F131LOC_RS05475 | 1226081..1226995 | - | 915 | WP_010301277.1 | SPFH/Band 7/PHB domain protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 61 a.a. Molecular weight: 6512.68 Da Isoelectric Point: 10.3299
>T181944 WP_103941744.1 NZ_CP065030:1221614-1221796 [Pectobacterium versatile]
MTSTDLIKELAAAGCECKRHNGGSHQIWWSPITGKTFPVPHPKKDLPLGTVKSIKKMAGI
MTSTDLIKELAAAGCECKRHNGGSHQIWWSPITGKTFPVPHPKKDLPLGTVKSIKKMAGI
Download Length: 183 bp
>T181944 NZ_CP086220:c1011104-1010997 [Escherichia coli]
ATGACGCTCGCGAAGTTTGCCATGATTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGGATTATTACCGCAGCGAT
TGTCGGCTGGTGGCGTAACCGGAAGTAA
ATGACGCTCGCGAAGTTTGCCATGATTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGGATTATTACCGCAGCGAT
TGTCGGCTGGTGGCGTAACCGGAAGTAA
Antitoxin
Download Length: 144 a.a. Molecular weight: 16036.95 Da Isoelectric Point: 4.3145
>AT181944 WP_103970630.1 NZ_CP065030:1221819-1222250 [Pectobacterium versatile]
MFFSVGVETPKDDATAYGLIVPALCTDDYGCFSAADSQQEIARMAREAILTIIDEAVSRGNLDIKRLNDAGHLIYAAIPD
FADYDSWFVLDVDLSAFEGKPQRLNISLPDTLIQRIDNRVREQPGTYRDRSHFLAEAARHELE
MFFSVGVETPKDDATAYGLIVPALCTDDYGCFSAADSQQEIARMAREAILTIIDEAVSRGNLDIKRLNDAGHLIYAAIPD
FADYDSWFVLDVDLSAFEGKPQRLNISLPDTLIQRIDNRVREQPGTYRDRSHFLAEAARHELE
Download Length: 432 bp
>AT181944 NZ_CP086220:1011157-1011218 [Escherichia coli]
TGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT
TGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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