181943

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) Hha-TomB/-
Location 1184254..1184879 Replicon chromosome
Accession NZ_CP065030
Organism Pectobacterium versatile strain F131

Toxin (Protein)


Gene name Hha Uniprot ID C6DB72
Locus tag F131LOC_RS05290 Protein ID WP_005976087.1
Coordinates 1184254..1184457 (-) Length 68 a.a.

Antitoxin (Protein)


Gene name TomB Uniprot ID C6DB73
Locus tag F131LOC_RS05295 Protein ID WP_005976089.1
Coordinates 1184511..1184879 (-) Length 123 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
F131LOC_RS05260 1179713..1180051 + 339 WP_002208627.1 P-II family nitrogen regulator -
F131LOC_RS05265 1180091..1181377 + 1287 WP_161973278.1 ammonium transporter AmtB -
F131LOC_RS05270 1181513..1182376 - 864 WP_040031226.1 acyl-CoA thioesterase II -
F131LOC_RS05275 1182589..1183170 + 582 WP_103970616.1 YbaY family lipoprotein -
F131LOC_RS05280 1183190..1183510 - 321 WP_015839360.1 MGMT family protein -
F131LOC_RS05290 1184254..1184457 - 204 WP_005976087.1 hemolysin expression modulator Hha Toxin
F131LOC_RS05295 1184511..1184879 - 369 WP_005976089.1 Hha toxicity modulator TomB Antitoxin
F131LOC_RS05300 1185477..1185620 - 144 WP_005976091.1 type B 50S ribosomal protein L36 -
F131LOC_RS05305 1185637..1185885 - 249 WP_039506474.1 type B 50S ribosomal protein L31 -
F131LOC_RS05310 1186121..1189249 - 3129 WP_103941781.1 efflux RND transporter permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Haemolysin expression modulating, HHA

(8-64)

Antitoxin

Biofilm formation regulator YbaJ

(1-118)


Sequences

Toxin        


Download         Length: 68 a.a.        Molecular weight: 8145.52 Da        Isoelectric Point: 8.9008

>T181943 WP_005976087.1 NZ_CP065030:c1184457-1184254 [Pectobacterium versatile]
MKKIDYLMRLRKCTTIDTLERVIEKNKYELSNDELEMFFSAADHRLAELTMNKLYDKVPTAVWRYVR

Download         Length: 204 bp

>T181943 NZ_CP086220:c1010569-1010462 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCGGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 123 a.a.        Molecular weight: 14032.77 Da        Isoelectric Point: 4.4787

>AT181943 WP_005976089.1 NZ_CP065030:c1184879-1184511 [Pectobacterium versatile]
MDEYTPKHYDIAQLRFLCENLCDESIATLGDSSHGWVNDPTSAINLQLNELIEHIATFILTFKIKYPNESELSEQVEKYL
DDTYVLFSNYGINDAELRRWQKSKAKLFGMFSGENVCTPAKT

Download         Length: 369 bp

>AT181943 NZ_CP086220:1010617-1010683 [Escherichia coli]
GTTCTGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTAAACCTCTCAACGTGCGGGGGTTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1D7Z3F0

Antitoxin

Source ID Structure
AlphaFold DB A0A1D7Z3G5

References