Detailed information of TA system TA181942

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/Cpta(toxin)
• Location: 725826..726486
• Replicon: chromosome
• Accession: NZ_CP065030
• Organism: Pectobacterium versatile strain F131

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: -
• Locus tag: F131LOC_RS03255
• Protein ID: WP_103861404.1
• Coordinates: 726073..726486 (+)
• Length: 138 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: A0A1V2R9A9
• Locus tag: F131LOC_RS03250
• Protein ID: WP_039355397.1
• Coordinates: 725826..726092 (+)
• Length: 89 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
F131LOC_RS03230	721728..722732	-	1005	WP_103971793.1	substrate-binding domain-containing protein	-
F131LOC_RS03235	722787..723395	-	609	WP_095701613.1	HD domain-containing protein	-
F131LOC_RS03240	723674..724321	+	648	WP_103183036.1	hemolysin III family protein	-
F131LOC_RS03245	724589..725590	-	1002	WP_103971792.1	tRNA-modifying protein YgfZ	-
F131LOC_RS03250	725826..726092	+	267	WP_039355397.1	FAD assembly factor SdhE	Antitoxin
F131LOC_RS03255	726073..726486	+	414	WP_103861404.1	protein YgfX	Toxin
F131LOC_RS03260	726555..727490	+	936	WP_103861403.1	23S rRNA (adenine(1618)-N(6))-methyltransferase RlmF	-
F131LOC_RS03265	727556..727879	-	324	WP_103971791.1	hypothetical protein	-
F131LOC_RS03270	727908..728426	-	519	WP_103971790.1	flavodoxin FldB	-
F131LOC_RS03275	728769..729155	-	387	WP_103861400.1	thioesterase family protein	-
F131LOC_RS03280	729380..730708	-	1329	WP_103861399.1	MHS family MFS transporter	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Inner membrane protein YgfX (2-132)

Antitoxin

• Flavinator of succinate dehydrogenase (8-79)

Sequences

Toxin

Protein

• Length: 138 a.a.
• Molecular weight: 16359.31 Da
• Isoelectric Point: 10.7911

>T181942 WP_103861404.1 NZ_CP065030:726073-726486 [Pectobacterium versatile]
VAQWRCDLRVSWRMQLLSLVVHGLLVLFILLAPWPDGYAWLWLCLVTMVMFGFIRSQRNIKSRQGEIVLLSETTLNWRQQ
EWQIVKRPWLLKNGVLLSLQAVNAKDKQQLWLASDSMGDDEWRHLRQLLLQQKHWAR

Nucleotide

• Length: 414 bp

>T181942 NZ_CP086220:c208388-208170 [Escherichia coli]
ATGTCCGAAAAACCTTTAACGAAAACCGATTATTTAATGCGTTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGTGT
TATCGAGAAAAATAAATACGAATTATCAGATAATGAACTGGCGGTATTTTACTCAGCCGCAGATCACCGCCTCGCCGAAT
TGACCATGAATAAACTATACGACAAGATCCCTTCCTCAGTATGGAAATTTATTCGCTAA

Antitoxin

Protein

• Length: 89 a.a.
• Molecular weight: 10506.99 Da
• Isoelectric Point: 6.2223

>AT181942 WP_039355397.1 NZ_CP065030:725826-726092 [Pectobacterium versatile]
MEIDNKSRIHWACRRGMRELDIAIMPFFEHDYDTLNDTDKRTFVRLLQSDDPDLFNWLMNHGEPKDGELKRMISLIQTRN
KDRGPVAM

Nucleotide

• Length: 267 bp

>AT181942 NZ_CP086220:c208788-208414 [Escherichia coli]
ATGGATGAATACTCACCCAAAAGACATGATATCGCACAGCTTAAGTTTCTCTGTGAAACCCTGTATCATGACTGCCTTGC
AAACCTTGAAGAAAGCAATCATGGCTGGGTTAACGACCCAACCTCGGCGATCAACCTCCAGTTGAATGAACTGATTGAGC
ATATTGCGACCTTCGCACTTAATTACAAAATTAAGTATAATGAAGACAATAAGCTCATTGAGCAGATCGACGAATATCTG
GATGACACCTTTATGTTGTTCAGTAGTTATGGTATTAATATGCAGGATCTTCAGAAATGGCGGAAGTCAGGTAATCGACT
ATTCCGTTGTTTTGTCAATGCGACGAAAGAGAATCCTGCGAGTTTATCTTGTTAG

Structures

Antitoxin

• AlphaFold DB: A0A1V2R9A9