Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | tacAT/DUF1778(antitoxin) |
| Location | 572431..573215 | Replicon | chromosome |
| Accession | NZ_CP065030 | ||
| Organism | Pectobacterium versatile strain F131 | ||
Toxin (Protein)
| Gene name | TacT2 | Uniprot ID | - |
| Locus tag | F131LOC_RS02520 | Protein ID | WP_103972008.1 |
| Coordinates | 572721..573215 (+) | Length | 165 a.a. |
Antitoxin (Protein)
| Gene name | TacA2 | Uniprot ID | A0A855MHZ3 |
| Locus tag | F131LOC_RS02515 | Protein ID | WP_010301483.1 |
| Coordinates | 572431..572724 (+) | Length | 98 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| F131LOC_RS02485 | 568791..569006 | + | 216 | Protein_480 | ATP-binding cassette domain-containing protein | - |
| F131LOC_RS02490 | 569003..569215 | + | 213 | Protein_481 | alpha-D-ribose 1-methylphosphonate 5-triphosphate diphosphatase | - |
| F131LOC_RS02495 | 569334..569903 | + | 570 | WP_103861699.1 | ribose 1,5-bisphosphokinase | - |
| F131LOC_RS02500 | 569942..570715 | + | 774 | WP_103972006.1 | phosphonate metabolism protein PhnP | - |
| F131LOC_RS02505 | 570807..571070 | - | 264 | WP_010286385.1 | DUF2798 domain-containing protein | - |
| F131LOC_RS02510 | 571199..572101 | + | 903 | WP_103972007.1 | LysR family transcriptional regulator | - |
| F131LOC_RS02515 | 572431..572724 | + | 294 | WP_010301483.1 | DUF1778 domain-containing protein | Antitoxin |
| F131LOC_RS02520 | 572721..573215 | + | 495 | WP_103972008.1 | GNAT family N-acetyltransferase | Toxin |
| F131LOC_RS02525 | 573277..573447 | + | 171 | Protein_488 | helix-turn-helix domain-containing protein | - |
| F131LOC_RS02535 | 573778..574623 | + | 846 | WP_103972009.1 | AraC family transcriptional regulator | - |
| F131LOC_RS02540 | 574659..575249 | + | 591 | WP_103941983.1 | LysE family translocator | - |
| F131LOC_RS02545 | 575246..575821 | - | 576 | WP_040030982.1 | transcriptional regulator | - |
| F131LOC_RS02550 | 575985..577715 | - | 1731 | WP_103972010.1 | protein-disulfide reductase DsbD | - |
| F131LOC_RS02555 | 577691..578023 | - | 333 | WP_010286405.1 | divalent cation tolerance protein CutA | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 165 a.a. Molecular weight: 17632.43 Da Isoelectric Point: 7.2922
>T181941 WP_103972008.1 NZ_CP065030:572721-573215 [Pectobacterium versatile]
MISAPEPLHAEHVFSSFCCGVESMDNWLKQRAMKNQVTGASRTFVSCDGSKVLAYYSLASSAVATNAAPGRFRRNMPDPI
PVVVLGRLAVDTSLHGQGVGRALVRDAGLRVIQVADTIGIRGMLVHALSDEAREFYLRVGFEPSPIDPMMLMVTLGDLVG
SLSI
MISAPEPLHAEHVFSSFCCGVESMDNWLKQRAMKNQVTGASRTFVSCDGSKVLAYYSLASSAVATNAAPGRFRRNMPDPI
PVVVLGRLAVDTSLHGQGVGRALVRDAGLRVIQVADTIGIRGMLVHALSDEAREFYLRVGFEPSPIDPMMLMVTLGDLVG
SLSI
Download Length: 495 bp
>T181941 NZ_CP086220:c174417-173875 [Escherichia coli]
ATGGTCGACAAGCATGAAGAGATTACTCTGCCCATAGTCCTCTCCTGTAATTATCAGTCTGATATTACTTATCCTGGGCA
AAAACAGTTTGATTGCGGTAACCCTGTTATCGATAAATTTGTACGCGCATCGCTAAAGAAAAGTGTGCGTAATAGCGACT
GTGCGGCTAAAGCACTTATTGACAGACAAAGTGGTGAACTGATCGGCATCTGTACTTTTACGGCATATTCGCTGGAAAAA
CAACGCGTTTCTGGCGTCCTTCAGGGTTCACAACCTTCAGAAATTGGTGTTGTCAGATTAGTCATGTTGGGGGTAGCACG
GAAGTATCAAAAGCGGGGCTTTGGTCAGGACCTACTATGTGATTTTTTTGAACATGTAAAAATAATTCACCAGGCATTAC
CAATTAAAGGGGTTTATCTTGATGCTGACCCTGCCGCCATTAATTTTTATGCTCGTCTCGGCTTTGTTCAGCTTTCAGCG
ACACCAAATGCTTTTGGTGCTGTACCTATGTTTTTGGCGATTCAGCATATTCTCGCGGCTTAG
ATGGTCGACAAGCATGAAGAGATTACTCTGCCCATAGTCCTCTCCTGTAATTATCAGTCTGATATTACTTATCCTGGGCA
AAAACAGTTTGATTGCGGTAACCCTGTTATCGATAAATTTGTACGCGCATCGCTAAAGAAAAGTGTGCGTAATAGCGACT
GTGCGGCTAAAGCACTTATTGACAGACAAAGTGGTGAACTGATCGGCATCTGTACTTTTACGGCATATTCGCTGGAAAAA
CAACGCGTTTCTGGCGTCCTTCAGGGTTCACAACCTTCAGAAATTGGTGTTGTCAGATTAGTCATGTTGGGGGTAGCACG
GAAGTATCAAAAGCGGGGCTTTGGTCAGGACCTACTATGTGATTTTTTTGAACATGTAAAAATAATTCACCAGGCATTAC
CAATTAAAGGGGTTTATCTTGATGCTGACCCTGCCGCCATTAATTTTTATGCTCGTCTCGGCTTTGTTCAGCTTTCAGCG
ACACCAAATGCTTTTGGTGCTGTACCTATGTTTTTGGCGATTCAGCATATTCTCGCGGCTTAG
Antitoxin
Download Length: 98 a.a. Molecular weight: 10930.52 Da Isoelectric Point: 10.1968
>AT181941 WP_010301483.1 NZ_CP065030:572431-572724 [Pectobacterium versatile]
MPVTNSVSVKRETLNLRIKPAERDLIDRAAKARGKNRTDFVLEAARAAAEEALIDQRIIMADPDAYQEFLARLDQTPSPN
AALRKTMQTPAPWEQKK
MPVTNSVSVKRETLNLRIKPAERDLIDRAAKARGKNRTDFVLEAARAAAEEALIDQRIIMADPDAYQEFLARLDQTPSPN
AALRKTMQTPAPWEQKK
Download Length: 294 bp
>AT181941 NZ_CP086220:c174712-174401 [Escherichia coli]
ATGCCTGGAAAAACAGCCACTCTACCCGATGTCGATAAAACGCTGAAAAATGCGCGGGTCGAACTCAAAACTAGTCCCGA
CGCCAAAAACAAACTTCGTGAAGCTGCGCAAGCCGTTGGGGTAGATTTAAGCGCTTTTATTTTGAGCGCTGCTATGGAAC
GCGCCGAAAGTGTGCTTGATAACCAACGTCGCCGTGAGCTTTCGAATCAAAGCTGGGAACTGATGAACCAACTCATCGCT
GAACCTGCTCAACCGACGCTCGCCCTCAAGGCGTTAATGAAAAGGAAAAACAGCGATGGTCGACAAGCATGA
ATGCCTGGAAAAACAGCCACTCTACCCGATGTCGATAAAACGCTGAAAAATGCGCGGGTCGAACTCAAAACTAGTCCCGA
CGCCAAAAACAAACTTCGTGAAGCTGCGCAAGCCGTTGGGGTAGATTTAAGCGCTTTTATTTTGAGCGCTGCTATGGAAC
GCGCCGAAAGTGTGCTTGATAACCAACGTCGCCGTGAGCTTTCGAATCAAAGCTGGGAACTGATGAACCAACTCATCGCT
GAACCTGCTCAACCGACGCTCGCCCTCAAGGCGTTAATGAAAAGGAAAAACAGCGATGGTCGACAAGCATGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|