Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 2031693..2032254 Replicon chromosome
Accession NZ_CP064942
Organism Pontivivens sp. MT2928

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag I0K15_RS09910 Protein ID WP_196105272.1
Coordinates 2031979..2032254 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag I0K15_RS09905 Protein ID WP_196105271.1
Coordinates 2031693..2031992 (+) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I0K15_RS09880 2026731..2028068 - 1338 WP_196105268.1 DGQHR domain-containing protein -
I0K15_RS09885 2028087..2028545 - 459 WP_196105269.1 GIY-YIG nuclease family protein -
I0K15_RS09890 2028936..2029976 + 1041 WP_196105270.1 class I SAM-dependent methyltransferase -
I0K15_RS09895 2030014..2031155 - 1142 Protein_1951 IS3 family transposase -
I0K15_RS09900 2031212..2031625 + 414 Protein_1952 hypothetical protein -
I0K15_RS09905 2031693..2031992 + 300 WP_196105271.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
I0K15_RS09910 2031979..2032254 + 276 WP_196105272.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
I0K15_RS09915 2032634..2033775 + 1142 Protein_1955 IS3 family transposase -
I0K15_RS09920 2033753..2034361 + 609 WP_196105273.1 type IV secretory system conjugative DNA transfer family protein -
I0K15_RS09925 2034802..2036085 + 1284 WP_196105274.1 diaminopimelate decarboxylase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 2012981..2074609 61628


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(4-57)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10348.90 Da        Isoelectric Point: 5.0760

>T181906 WP_196105272.1 NZ_CP064942:2031979-2032254 [Pontivivens sp. MT2928]
VPRLEWKIAAVSDLLAIIDYISDDNPDAAQALKNEIEEKVSRLPTNPHLYRVGRVDGTREMVVRPNYIVVYSETPEVVTI
LRVLHAAQLWP

Download         Length: 276 bp

>T181906 NZ_CP086201:c1071221-1071003 [Enterobacter roggenkampii]
ATGTCTGATAAACCACTCACAAAAATCGATTATTTGATGCGCTTACGACGTTGTCAGTCAATTGACACCCTCGAACGCGT
GATTGAAAAGAATAAATACGAGCTTTCTGATAATGAACTGGCCGTATTTTATTCAGCCGCTGACCATCGTCTTGCTGAGC
TGACCATGAATAAGTTGTATGACAAAATCCCTACTTCTGTATGGAAATTTGTCCGTTAA

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 10501.94 Da        Isoelectric Point: 5.0608

>AT181906 WP_196105271.1 NZ_CP064942:2031693-2031992 [Pontivivens sp. MT2928]
MPAQTSMIHVRVDDQLKTDASEALAGVGLTVSDAVRILLTRVAAEGGLPAGLTADPDAYDAWFRAKVQEAIDDPRPPAPH
AQIMAEAQALIDGKRRAKT

Download         Length: 300 bp

>AT181906 NZ_CP086201:c1071623-1071249 [Enterobacter roggenkampii]
ATGGACGAGTACTCGCCAAAAAGGCATGATATCGCGCAGTTGAAATTTCTCTGCGAATCCTTGTACCATGACTGCCTTGC
CAACCTTGATGAAAGCAACCATGGCTGGGTAAACGACCCAACGTCTGCCATCAATTTACAGTTGAATGAGCTGATAGAGC
ATATCGCAACCTTCGCACTTAATTATAAAATTAAGTACAATGAAGATAATAAGCTCATTGAGCAAATTGATGAATACCTG
GACGACACCTTTATGTTGTTCAGTAGTTACGGCATTAACGCCCAGGATTTGCAAAAATGGCGTAAATCGGGAAACCGGCT
ATTCCGCTGTTTCGTCAACGTGAGCAGAGCTAACCCGGTTAGCCTTTCCTGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References