181904

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-DinJ
Location 1551649..1552171 Replicon chromosome
Accession NZ_CP064936
Organism Treponema sp. RCC2812

Toxin (Protein)


Gene name relB Uniprot ID -
Locus tag IWA51_RS07240 Protein ID WP_198441944.1
Coordinates 1551649..1551912 (-) Length 88 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag IWA51_RS07245 Protein ID WP_177528308.1
Coordinates 1551905..1552171 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IWA51_RS07220 1547117..1548283 + 1167 WP_198441941.1 glycosyltransferase -
IWA51_RS07225 1548321..1548746 - 426 WP_177528312.1 GtrA family protein -
IWA51_RS07230 1548743..1549672 - 930 WP_198441942.1 glycosyltransferase family 2 protein -
IWA51_RS07235 1549672..1551414 - 1743 WP_198441943.1 glucosyltransferase domain-containing protein -
IWA51_RS07240 1551649..1551912 - 264 WP_198441944.1 Txe/YoeB family addiction module toxin Toxin
IWA51_RS07245 1551905..1552171 - 267 WP_177528308.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
IWA51_RS07250 1552305..1552679 + 375 WP_177528307.1 FdtA/QdtA family cupin domain-containing protein -
IWA51_RS07255 1552694..1553800 + 1107 WP_198441945.1 DegT/DnrJ/EryC1/StrS family aminotransferase -
IWA51_RS07260 1553802..1554731 + 930 WP_177528305.1 glycosyltransferase family 2 protein -
IWA51_RS07265 1554749..1556596 + 1848 WP_198441946.1 hypothetical protein -
IWA51_RS07270 1556593..1556949 + 357 WP_177528303.1 EamA family transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(1-85)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-87)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10413.66 Da        Isoelectric Point: 5.7103

>T181904 WP_198441944.1 NZ_CP064936:c1551912-1551649 [Treponema sp. RCC2812]
MTKVWDDSAWDDYVYWQGQDRNTLKKINSLLKDIESNGPNKGIGKPEPLKHELSGYYSRRIDEENRLVYTVENDMLKIIQ
CRTHYEY

Download         Length: 264 bp

>T181904 NZ_CP086201:c258462-258175 [Enterobacter roggenkampii]
ATGCATAAATTAACACCTTATGATCCCGCCAACGCGTTGGTGGATGACGAGGAAATCGCCGTGTTTATCGCTGATGCACT
AGAAACAGGCGACTCGACATATATCGCTAAAGCCCTTGGTGTTGTCGCGCGAGCCAAAGGCATGTCGAACATTTCACAGC
AAACCGGTTTATCACGTGAGCAGCTTTATCGGTCATTCAGTGATAAAGGAAACCCAACGCTCAAAACCACGCTCGCGGTC
ATGAAAGCATTGGGTTTTGGGCTAACACTCAAACACGCCGGGGATTAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10019.44 Da        Isoelectric Point: 8.5549

>AT181904 WP_177528308.1 NZ_CP064936:c1552171-1551905 [Treponema sp. RCC2812]
MAQTSVNIRMDTATKKSAEELFAQLGMNMTTAFNIFVRQSLRVGGIPFNITTKTGEGFYNPYNQRLLREAKERMDKGFGK
VHEIIEDD

Download         Length: 267 bp

>AT181904 NZ_CP086201:c258771-258469 [Enterobacter roggenkampii]
ATGAAGGAGATTGTTCAGACAGAATCCTTCCGACGCTGGGAGCAAAACTTAAAAGATCGACGAGCGAAGACCATTATCGC
TTCCCGCCTCTTTCGGTTGGCAAATGGCTTAGCGGGCGACGTTAAACCCGTGGGAGAAGGTATAAGTGAGCTAAGGATCC
ACTTTGGTCCGGGCTACAGGATCTATTTTAAAGACCAGGGCAATTACATCATCGTGCTGTTATGTGGTGGTGACAAAAGC
AGCCAGGCCAGAGACATACTGATGGCAAAAATGCTGAGCAATGTATCCCAATGGCAGGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References