Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VapB
Location 212319..212899 Replicon plasmid pBS3c
Accession NZ_CP064934
Organism Rhizobium phaseoli strain BS3

Toxin (Protein)


Gene name vapC Uniprot ID A0A192TJS5
Locus tag HER27_RS26575 Protein ID WP_010015189.1
Coordinates 212516..212899 (+) Length 128 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID A0A7X6EWP6
Locus tag HER27_RS26570 Protein ID WP_064826177.1
Coordinates 212319..212519 (+) Length 67 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HER27_RS26545 207325..207678 + 354 WP_064826182.1 hypothetical protein -
HER27_RS26550 207707..208603 - 897 WP_064826181.1 GGDEF domain-containing protein -
HER27_RS26555 208842..209486 - 645 WP_141489223.1 hypothetical protein -
HER27_RS26560 209738..209920 - 183 WP_081277771.1 DUF1778 domain-containing protein -
HER27_RS26565 210034..212151 - 2118 WP_064826178.1 carboxy terminal-processing peptidase -
HER27_RS26570 212319..212519 + 201 WP_064826177.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
HER27_RS26575 212516..212899 + 384 WP_010015189.1 type II toxin-antitoxin system VapC family toxin Toxin
HER27_RS26580 212978..214939 - 1962 WP_064826298.1 elongation factor G -
HER27_RS26585 215274..217652 - 2379 WP_081277770.1 S8 family peptidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..413456 413456


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-113)

Antitoxin

Bacterial antitoxin of type II TA system, VapB

(1-42)


Sequences

Toxin        


Download         Length: 128 a.a.        Molecular weight: 14243.32 Da        Isoelectric Point: 6.8449

>T181898 WP_010015189.1 NZ_CP064934:212516-212899 [Rhizobium phaseoli]
VILADTSIWIDHFRHADSELRRIIEDDRLLCHPAVIGELALGSLRDRNNVIAFLAAQREAFVATHDEVMMMIDRHAVFSM
GIGYTDAHLMASVLLDRRAALWTRDKRLRAAAEKAGASLHTPDNARS

Download         Length: 384 bp

>T181898 NZ_CP086200:c1074183-1073854 [Xanthomonas oryzae pv. oryzae]
TTGCATCATGTCGCCGAACGCCGATGGCCGTTTCTGTTTACTGACAGCCACGCCTACTGCCAGTTGGCGAGCTTCTATTC
CGATTTATCTGATCTCGACAAGATCGACTGGCCGTTGCTCCAAGCACGCGATTTCCGGCGCGACCCAGACGACCCAGCCA
AGTTCGAGCGCTATCAGGCCGAGGCCCTGATTCACCGACACTTGCCGCTTGATGGCCTGCGCGGCATTGTGTGTCATACG
GATGGTTTGAAACAGACCATCGAGCGGCAACTCCAAGAGCGAAACCTGAAATTGCCGGTTCATACCCGCACCGATTGGTA
TTTCCGATGA

Antitoxin


Download         Length: 67 a.a.        Molecular weight: 7299.46 Da        Isoelectric Point: 11.6903

>AT181898 WP_064826177.1 NZ_CP064934:212319-212519 [Rhizobium phaseoli]
MRSTINLDDTLMERARFLTGTKETATLVRQALETLVRVESGKRLIALGGTMPDAEAAPRRRSAARK

Download         Length: 201 bp

>AT181898 NZ_CP086200:c1073857-1073438 [Xanthomonas oryzae pv. oryzae]
ATGATCACGTTTACACAAGGCAATCTACTGGAGTCTGGCGCAGAGGCGCTGGTCAACACCGTCAACACCGTCGGCGTGAT
GGGCAAGGGCATCGCGCTGATGTTCAAGGAGCGCTTCAAGGAGAACTTCCTCCGATATGCCGCCGCCTGCAAAGACAACC
AAGTGCGCATTGGCAAAATTTTCGTCACCGAAGTCAACGAACTGGACGGGCCACGCTGGATCATCAATTTTCCGACCAAA
CAGCACTGGCGTGGCGATTCCCGCATCGAATGGATCACTGAAGGATTGCAGGACTTGCACCGTTTTCTGATCGAGAACAA
AGTCAAATCCATTGCCATCCCGCCACTGGGCGCGGGCAATGGAGGATTGGACTGGGCCGAGGTGCGCCCACTGATCGAAG
AAGTACTAGGGAACCTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A192TJS5

Antitoxin

Source ID Structure
AlphaFold DB A0A7X6EWP6

References