Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1-Phd
Location 3183805..3184523 Replicon chromosome
Accession NZ_CP064931
Organism Rhizobium phaseoli strain BS3

Toxin (Protein)


Gene name vapC Uniprot ID B3PRC0
Locus tag HER27_RS15285 Protein ID WP_012482827.1
Coordinates 3184065..3184523 (+) Length 153 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID A0A192T4C6
Locus tag HER27_RS15280 Protein ID WP_064821400.1
Coordinates 3183805..3184068 (+) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HER27_RS15265 3179056..3179493 + 438 WP_064821401.1 nucleoside deaminase -
HER27_RS15270 3179765..3180394 - 630 WP_012482830.1 hypothetical protein -
HER27_RS15275 3180526..3183453 - 2928 WP_064823064.1 isoleucine--tRNA ligase -
HER27_RS15280 3183805..3184068 + 264 WP_064821400.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
HER27_RS15285 3184065..3184523 + 459 WP_012482827.1 type II toxin-antitoxin system VapC family toxin Toxin
HER27_RS15290 3184550..3185533 - 984 WP_064821399.1 bifunctional riboflavin kinase/FAD synthetase -
HER27_RS15295 3185548..3186396 - 849 WP_012482825.1 TIGR01459 family HAD-type hydrolase -
HER27_RS15300 3186731..3187027 + 297 WP_004675403.1 co-chaperone GroES -
HER27_RS15305 3187098..3188735 + 1638 WP_012482824.1 chaperonin GroEL -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-127)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(7-56)


Sequences

Toxin        


Download         Length: 153 a.a.        Molecular weight: 17015.19 Da        Isoelectric Point: 6.8817

>T181896 WP_012482827.1 NZ_CP064931:3184065-3184523 [Rhizobium phaseoli]
VIGWLLDTNVIAALINPNGAPSVKSWAAAQDENQMFISVLTLAEYDKGIENLPEDDRNRYRYIAARDALEERFSQRTLSL
SDAAVRHWGAISGRIKLRTGHAPPVIDTMLAATAIEHNLYLVTRNAKDTRFSGAAVFDPWTHDPNQFPLSRR

Download         Length: 459 bp

>T181896 NZ_CP086200:423878-424030 [Xanthomonas oryzae pv. oryzae]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCTGGCGC
TGGCAAGGACTTGCAGGGCGCGGGTGGGAAGGTCGAGAAAACGGCCGAAAAATGCAGCGATGGTAAGTGCTGA

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 10188.70 Da        Isoelectric Point: 8.5940

>AT181896 WP_064821400.1 NZ_CP064931:3183805-3184068 [Rhizobium phaseoli]
MRKIVKQSWKLEDAKARFSEVVRRARSEGPQRVTVRGRDSVVIISVEELERLTKAEPRKPLVDFMESLALKEFDLEREAD
YGRDVEL

Download         Length: 264 bp

>AT181896 NZ_CP086200:424094-424228 [Xanthomonas oryzae pv. oryzae]
ATGAAGCGTGCAATTGTGCTGCTCGTGCTGTCCATGTTGTCGGTCGGTCTGCTGTCGGGCTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGAAGGGCGCCGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0M3GMR1

Antitoxin

Source ID Structure
AlphaFold DB A0A192T4C6

References