181891

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /PIN(toxin)
Location 4986784..4987439 Replicon chromosome
Accession NZ_CP064923
Organism Acaryochloris marina S15

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag I1H34_RS22775 Protein ID WP_249369523.1
Coordinates 4986784..4987203 (-) Length 140 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag I1H34_RS22780 Protein ID WP_212663184.1
Coordinates 4987200..4987439 (-) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I1H34_RS22760 (I1H34_22720) 4982485..4983963 - 1479 WP_212663181.1 alpha-amylase -
I1H34_RS22765 (I1H34_22725) 4984193..4985269 - 1077 WP_212663182.1 magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase -
I1H34_RS22770 (I1H34_22730) 4985548..4986732 + 1185 WP_212663183.1 8-amino-7-oxononanoate synthase -
I1H34_RS22775 (I1H34_22735) 4986784..4987203 - 420 WP_249369523.1 PIN domain-containing protein Toxin
I1H34_RS22780 (I1H34_22740) 4987200..4987439 - 240 WP_212663184.1 DUF2281 domain-containing protein Antitoxin
I1H34_RS22785 (I1H34_22745) 4988050..4988280 - 231 WP_212663185.1 hypothetical protein -
I1H34_RS22790 (I1H34_22750) 4988448..4988900 - 453 WP_212663186.1 GNAT family N-acetyltransferase -
I1H34_RS22795 (I1H34_22755) 4989051..4989437 - 387 WP_212663187.1 VOC family protein -
I1H34_RS22800 (I1H34_22760) 4989443..4991122 - 1680 WP_249369525.1 ABC transporter ATP-binding protein -
I1H34_RS22805 (I1H34_22765) 4991266..4991898 + 633 WP_212663188.1 chorismate lyase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(6-119)

Antitoxin

Domain of unknown function DUF2281

(6-70)


Sequences

Toxin        


Download         Length: 140 a.a.        Molecular weight: 15280.70 Da        Isoelectric Point: 4.4335

>T181891 WP_249369523.1 NZ_CP064923:c4987203-4986784 [Acaryochloris marina S15]
VSLRVKVLIDTNVVLDVLLERDPFVENAIALFEQIELGHVVGAIAATTLTNIFYIIRKSESREAAISAVHRLLIGLQFCA
VDRQTVETALGLGLKDFEDSIQLACALLNQLDGIVTRDSKDFISSQLPIYSPTELLSQL

Download         Length: 420 bp

>T181891 NZ_CP086197:4521767-4522048 [Xanthomonas oryzae]
ATGATCAGGAGCTTTATCGACAAGGACGCCGAAAAGATCTGGCTGGGTGAGCGTTCCCGCCGGTTGCCTGCCGACATCCA
ATTGGTCGCGCGCCGCAAGTTGCGCATGCTCAATGCCGCCGCGCATCTCGACGATCTGCGGATCCCGCCCGCCAACCGGC
TGGAAGCGTTGAAGGGCCAGCAGCGCGGCCAGTACAGCATCCGGATCAACGATCAATGGCGCATCTGCTTCCGATGGATG
GAAGGCGATGTGGTCCAGGTCGAAATCGTCGATTACCACTGA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8775.80 Da        Isoelectric Point: 5.5354

>AT181891 WP_212663184.1 NZ_CP064923:c4987439-4987200 [Acaryochloris marina S15]
MTAAEKLYELIQSLPESQVNEVLNFAEFLHHKQLNSSQSQAIPPGTLTGLRGIAKGPKAASSDHELQAEYTDYLTQKYQ

Download         Length: 240 bp

>AT181891 NZ_CP086197:4522066-4522356 [Xanthomonas oryzae]
ATGACGGTCCTACCCAATATCCATCCTGGCGACATTCTGCTTGAGGAGTTTCTCGAGCCTCTGGGCATCAGCCAGAACGC
ACTGGCACGCGCCACCGGCGTCCCGCCGCGCCGTATCAACGAAATCGTGCTGGGCAAGCGCGGCATCACTGCCGACACTG
CCGTGCGTCTGGCCGCCGCGTTGGGCACCTCCGAGCGCTTCTGGCTGGGCCTGCAGGCCGACTACGAGCTGGAACAGGCG
CATCGCGCGCTGGGCGATTTGCCGGCACGGATCAAGCGGCTGGCGGCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References