Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) relB-yefM/YoeB-RelB
Location 4196574..4197084 Replicon chromosome
Accession NZ_CP064923
Organism Acaryochloris marina S15

Toxin (Protein)


Gene name relB Uniprot ID -
Locus tag I1H34_RS19210 Protein ID WP_212662580.1
Coordinates 4196821..4197084 (+) Length 88 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag I1H34_RS19205 Protein ID WP_212662579.1
Coordinates 4196574..4196828 (+) Length 85 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I1H34_RS19185 (I1H34_19170) 4192439..4192912 - 474 WP_212662575.1 Hsp20/alpha crystallin family protein -
I1H34_RS19190 (I1H34_19175) 4193240..4195198 + 1959 WP_212662576.1 tetratricopeptide repeat protein -
I1H34_RS19195 (I1H34_19180) 4195243..4195731 + 489 WP_212662577.1 GNAT family N-acetyltransferase -
I1H34_RS19200 (I1H34_19185) 4195795..4196511 + 717 WP_212662578.1 hypothetical protein -
I1H34_RS19205 (I1H34_19190) 4196574..4196828 + 255 WP_212662579.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
I1H34_RS19210 (I1H34_19195) 4196821..4197084 + 264 WP_212662580.1 Txe/YoeB family addiction module toxin Toxin
I1H34_RS19215 (I1H34_19200) 4197110..4198183 - 1074 WP_249369245.1 ISKra4 family transposase -
I1H34_RS19220 (I1H34_19205) 4198229..4198501 - 273 WP_212661590.1 hypothetical protein -
I1H34_RS19225 (I1H34_19210) 4198614..4200149 - 1536 WP_212662581.1 NAD(P)/FAD-dependent oxidoreductase -
I1H34_RS19230 (I1H34_19215) 4200204..4201793 - 1590 WP_249369396.1 nitrate ABC transporter substrate-binding protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(6-87)

Antitoxin

(1-74)


Sequences


Toxin        


Download         Length: 88 a.a.        Molecular weight: 10404.78 Da        Isoelectric Point: 9.3600

>T181890 WP_212662580.1 NZ_CP064923:4196821-4197084 [Acaryochloris marina S15]
MSSRKLAWTDAAWNDYLYWQGQDKKTLKRINKLIQATNNQPFEGIGKPEALRENLSGFWSRRIDETHRLVYAIDDHYLTI
IACRYHY

Download         Length: 264 bp

>T181890 NZ_CP086197:c3908729-3908577 [Xanthomonas oryzae]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCTGGCGC
TGGCAAGGACTTGCAGGGCGCGGGTGGGAAGGTCGAGAAAACGGCCGAAAAATGCAGCGATGGTAAGTGCTGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9468.59 Da        Isoelectric Point: 4.3046

>AT181890 WP_212662579.1 NZ_CP064923:4196574-4196828 [Acaryochloris marina S15]
MNIISFSEARSKLKAVFDRVVDDADYTIITRRDADDAVLMSLESFNSLLETVHLLKSPANAAHLEQSIAQYRQGQVTEQD
LLDE

Download         Length: 255 bp

>AT181890 NZ_CP086197:c3908513-3908379 [Xanthomonas oryzae]
ATGAAGCGTGCAATTGTGCTGCTCGTGCTGTCCATGTTGTCGGTCGGTCTGCTGTCGGGCTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGAAGGGCGCCGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References