Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | vapBC/VapC-StbC |
| Location | 3746565..3747210 | Replicon | chromosome |
| Accession | NZ_CP064923 | ||
| Organism | Acaryochloris marina S15 | ||
Toxin (Protein)
| Gene name | vapC | Uniprot ID | - |
| Locus tag | I1H34_RS17305 | Protein ID | WP_212662250.1 |
| Coordinates | 3746565..3746990 (-) | Length | 142 a.a. |
Antitoxin (Protein)
| Gene name | vapB | Uniprot ID | - |
| Locus tag | I1H34_RS17310 | Protein ID | WP_212662251.1 |
| Coordinates | 3746977..3747210 (-) | Length | 78 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| I1H34_RS17295 (I1H34_17280) | 3743099..3745666 | + | 2568 | WP_212662249.1 | leucine--tRNA ligase | - |
| I1H34_RS17300 (I1H34_17285) | 3745678..3746259 | - | 582 | WP_249369338.1 | alpha/beta hydrolase | - |
| I1H34_RS17305 (I1H34_17290) | 3746565..3746990 | - | 426 | WP_212662250.1 | type II toxin-antitoxin system VapC family toxin | Toxin |
| I1H34_RS17310 (I1H34_17295) | 3746977..3747210 | - | 234 | WP_212662251.1 | DNA-binding protein | Antitoxin |
| I1H34_RS17315 (I1H34_17300) | 3747304..3747708 | - | 405 | WP_212662252.1 | hypothetical protein | - |
| I1H34_RS17320 (I1H34_17305) | 3747860..3748825 | + | 966 | WP_212662253.1 | alpha/beta fold hydrolase | - |
| I1H34_RS17325 (I1H34_17310) | 3748890..3749858 | - | 969 | WP_212662254.1 | lysylphosphatidylglycerol synthase transmembrane domain-containing protein | - |
| I1H34_RS17330 (I1H34_17315) | 3749860..3751452 | - | 1593 | WP_212662255.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 142 a.a. Molecular weight: 15802.04 Da Isoelectric Point: 4.7249
>T181889 WP_212662250.1 NZ_CP064923:c3746990-3746565 [Acaryochloris marina S15]
MYLIDTNVISELRKQARADPGVRKFFQVAAEQKARLYISAITIGELRRGVELIRYRGDLPQASLLENWLQTILDSYADHI
LDFTEVEAQVWGCLCAPHPQNAIDKQIAAIALTRDLTLVTRNVSDFADTGASLINPFEIAD
MYLIDTNVISELRKQARADPGVRKFFQVAAEQKARLYISAITIGELRRGVELIRYRGDLPQASLLENWLQTILDSYADHI
LDFTEVEAQVWGCLCAPHPQNAIDKQIAAIALTRDLTLVTRNVSDFADTGASLINPFEIAD
Download Length: 426 bp
>T181889 NZ_CP086197:c3908513-3908379 [Xanthomonas oryzae]
ATGAAGCGTGCAATTGTGCTGCTCGTGCTGTCCATGTTGTCGGTCGGTCTGCTGTCGGGCTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGAAGGGCGCCGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA
ATGAAGCGTGCAATTGTGCTGCTCGTGCTGTCCATGTTGTCGGTCGGTCTGCTGTCGGGCTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGAAGGGCGCCGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA
Antitoxin
Download Length: 78 a.a. Molecular weight: 8768.91 Da Isoelectric Point: 4.4067
>AT181889 WP_212662251.1 NZ_CP064923:c3747210-3746977 [Acaryochloris marina S15]
MANLIVRNIDDSIVRALKMRASQNGVSAEAEHRKILEQVLFHPPQKSFSEVLCQIPQVGCDEDFERIQDDLAQDVFD
MANLIVRNIDDSIVRALKMRASQNGVSAEAEHRKILEQVLFHPPQKSFSEVLCQIPQVGCDEDFERIQDDLAQDVFD
Download Length: 234 bp
>AT181889 NZ_CP086197:c3908729-3908577 [Xanthomonas oryzae]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCTGGCGC
TGGCAAGGACTTGCAGGGCGCGGGTGGGAAGGTCGAGAAAACGGCCGAAAAATGCAGCGATGGTAAGTGCTGA
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCTGGCGC
TGGCAAGGACTTGCAGGGCGCGGGTGGGAAGGTCGAGAAAACGGCCGAAAAATGCAGCGATGGTAAGTGCTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|