Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 3746565..3747210 Replicon chromosome
Accession NZ_CP064923
Organism Acaryochloris marina S15

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag I1H34_RS17305 Protein ID WP_212662250.1
Coordinates 3746565..3746990 (-) Length 142 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag I1H34_RS17310 Protein ID WP_212662251.1
Coordinates 3746977..3747210 (-) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I1H34_RS17295 (I1H34_17280) 3743099..3745666 + 2568 WP_212662249.1 leucine--tRNA ligase -
I1H34_RS17300 (I1H34_17285) 3745678..3746259 - 582 WP_249369338.1 alpha/beta hydrolase -
I1H34_RS17305 (I1H34_17290) 3746565..3746990 - 426 WP_212662250.1 type II toxin-antitoxin system VapC family toxin Toxin
I1H34_RS17310 (I1H34_17295) 3746977..3747210 - 234 WP_212662251.1 DNA-binding protein Antitoxin
I1H34_RS17315 (I1H34_17300) 3747304..3747708 - 405 WP_212662252.1 hypothetical protein -
I1H34_RS17320 (I1H34_17305) 3747860..3748825 + 966 WP_212662253.1 alpha/beta fold hydrolase -
I1H34_RS17325 (I1H34_17310) 3748890..3749858 - 969 WP_212662254.1 lysylphosphatidylglycerol synthase transmembrane domain-containing protein -
I1H34_RS17330 (I1H34_17315) 3749860..3751452 - 1593 WP_212662255.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-122)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 142 a.a.        Molecular weight: 15802.04 Da        Isoelectric Point: 4.7249

>T181889 WP_212662250.1 NZ_CP064923:c3746990-3746565 [Acaryochloris marina S15]
MYLIDTNVISELRKQARADPGVRKFFQVAAEQKARLYISAITIGELRRGVELIRYRGDLPQASLLENWLQTILDSYADHI
LDFTEVEAQVWGCLCAPHPQNAIDKQIAAIALTRDLTLVTRNVSDFADTGASLINPFEIAD

Download         Length: 426 bp

>T181889 NZ_CP086197:c3908513-3908379 [Xanthomonas oryzae]
ATGAAGCGTGCAATTGTGCTGCTCGTGCTGTCCATGTTGTCGGTCGGTCTGCTGTCGGGCTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGAAGGGCGCCGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8768.91 Da        Isoelectric Point: 4.4067

>AT181889 WP_212662251.1 NZ_CP064923:c3747210-3746977 [Acaryochloris marina S15]
MANLIVRNIDDSIVRALKMRASQNGVSAEAEHRKILEQVLFHPPQKSFSEVLCQIPQVGCDEDFERIQDDLAQDVFD

Download         Length: 234 bp

>AT181889 NZ_CP086197:c3908729-3908577 [Xanthomonas oryzae]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCTGGCGC
TGGCAAGGACTTGCAGGGCGCGGGTGGGAAGGTCGAGAAAACGGCCGAAAAATGCAGCGATGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References