Detailed information of TA system TA181888

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): PumAB/COG3657-dnstrm_HI1420
• Location: 3738771..3739364
• Replicon: chromosome
• Accession: NZ_CP064923
• Organism: Acaryochloris marina S15

Toxin (Protein)

• Gene name: PumA
• Uniprot ID: -
• Locus tag: I1H34_RS17280
• Protein ID: WP_212662247.1
• Coordinates: 3739119..3739364 (-)
• Length: 82 a.a.

Antitoxin (Protein)

• Gene name: PumB
• Uniprot ID: -
• Locus tag: I1H34_RS17275
• Protein ID: WP_212662246.1
• Coordinates: 3738771..3739064 (-)
• Length: 98 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
I1H34_RS17255 (I1H34_17240)	3734317..3735402	-	1086	WP_212662243.1	IS630 family transposase	-
I1H34_RS17260 (I1H34_17245)	3736059..3736571	-	513	WP_212662244.1	hypothetical protein	-
I1H34_RS17265 (I1H34_17250)	3736867..3737154	-	288	WP_212666317.1	Mo-dependent nitrogenase C-terminal domain-containing protein	-
I1H34_RS17270 (I1H34_17255)	3737939..3738502	-	564	WP_212662245.1	Uma2 family endonuclease	-
I1H34_RS17275 (I1H34_17260)	3738771..3739064	-	294	WP_212662246.1	putative addiction module antidote protein	Antitoxin
I1H34_RS17280 (I1H34_17265)	3739119..3739364	-	246	WP_212662247.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
I1H34_RS17285 (I1H34_17270)	3739861..3742065	-	2205	WP_212662248.1	AAA family ATPase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Addiction module killer protein, predicted (1-80)

Antitoxin

• Uncharacterized protein HI1420 (5-94)

Sequences

Toxin

Protein

• Length: 82 a.a.
• Molecular weight: 9145.60 Da
• Isoelectric Point: 10.5231

>T181888 WP_212662247.1 NZ_CP064923:c3739364-3739119 [Acaryochloris marina S15]
MIEVRQTDIFANWFKKLRDRKAKARIQARIDRIEIGNFGDVAPVGEGVSELRIHYGPGYRVYFIQRGPVVVILLSGGDKG
S

Nucleotide

• Length: 246 bp

>T181888 NZ_CP086197:3253865-3254194 [Xanthomonas oryzae]
TTGCATCATGTCGCCGAACGCCGATGGCCGTTTCTGTTTACTGACAGCCACGCCTACTGCCAGTTGGCGAGCTTCTATTC
CGATTTATCTGATCTCGACAAGATCGACTGGCCGTTGCTCCAAGCACGCGATTTCCGGCGCGACCCAGACGACCCAGCCA
AGTTCGAGCGCTATCAGGCCGAGGCCCTGATTCACCGACACTTGCCGCTTGATGGCCTGCGCGGCATTGTGTGTCATACG
GATGGTTTGAAACAGACCATCGAGCGGCAACTCCAAGAGCGAAACCTGAAATTGCCGGTTCATACCCGCACCGATTGGTA
TTTCCGATGA

Antitoxin

Protein

• Length: 98 a.a.
• Molecular weight: 10614.06 Da
• Isoelectric Point: 4.4791

>AT181888 WP_212662246.1 NZ_CP064923:c3739064-3738771 [Acaryochloris marina S15]
MAISITRWDSAEHLKTEEDIQLYLEACLEEAEDDPALIIHALGVVARAKNMSQLSRDTGLSREGLYKALSPDGNPTFSTI
AEVTKALGFKLTIQPTP

Nucleotide

• Length: 294 bp

>AT181888 NZ_CP086197:3254191-3254610 [Xanthomonas oryzae]
ATGATCACGTTTACACAAGGCAATCTACTGGAGTCTGGCGCAGAGGCGCTGGTCAACACCGTCAACACCGTCGGCGTGAT
GGGCAAGGGCATCGCGCTGATGTTCAAGGAGCGCTTCAAGGAGAACTTCCTCCGATATGCCGCCGCCTGCAAAGACAACC
AAGTGCGCATTGGCAAAATTTTCGTCACCGAAGTCAACGAACTGGACGGGCCACGCTGGATCATCAATTTTCCGACCAAA
CAGCACTGGCGTGGCGATTCCCGCATCGAATGGATCACTGAAGGATTGCAGGACTTGCACCGTTTTCTGATCGAGAACAA
AGTCAAATCCATTGCCATCCCGCCACTGGGCGCGGGCAATGGAGGATTGGACTGGGCCGAGGTGCGCCCACTGATCGAAG
AAGTACTAGGGAACCTCTGA