Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/DUF433(antitoxin)
Location 3080588..3081168 Replicon chromosome
Accession NZ_CP064923
Organism Acaryochloris marina S15

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag I1H34_RS14250 Protein ID WP_212661751.1
Coordinates 3080588..3080941 (-) Length 118 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag I1H34_RS14255 Protein ID WP_212661752.1
Coordinates 3080938..3081168 (-) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I1H34_RS14230 (I1H34_14220) 3076788..3077474 + 687 WP_249369231.1 caspase family protein -
I1H34_RS14235 (I1H34_14225) 3077486..3078727 - 1242 WP_249369233.1 ISAs1 family transposase -
I1H34_RS14240 (I1H34_14230) 3078912..3080072 + 1161 WP_249369235.1 formylglycine-generating enzyme family protein -
I1H34_RS14245 (I1H34_14235) 3080224..3080595 + 372 WP_212661750.1 hypothetical protein -
I1H34_RS14250 (I1H34_14240) 3080588..3080941 - 354 WP_212661751.1 DUF5615 family PIN-like protein Toxin
I1H34_RS14255 (I1H34_14245) 3080938..3081168 - 231 WP_212661752.1 DUF433 domain-containing protein Antitoxin
I1H34_RS14260 (I1H34_14250) 3081266..3082429 - 1164 WP_212661753.1 pyridoxal phosphate-dependent aminotransferase -
I1H34_RS14265 (I1H34_14255) 3082429..3083097 - 669 WP_212661754.1 hypothetical protein -
I1H34_RS14270 (I1H34_14260) 3083103..3083846 - 744 WP_212661755.1 D-alanyl-D-alanine carboxypeptidase family protein -
I1H34_RS14275 (I1H34_14265) 3084258..3085799 + 1542 WP_249369237.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Domain of unknown function DUF5615

(1-79)

Antitoxin

Protein of unknown function DUF433

(10-65)


Sequences

Toxin        


Download         Length: 118 a.a.        Molecular weight: 13167.03 Da        Isoelectric Point: 4.1448

>T181886 WP_212661751.1 NZ_CP064923:c3080941-3080588 [Acaryochloris marina S15]
MKIWVDAQLPPTLAEWLSATFDDVEAAALRDLSLRDAQDIEIFEAARTENAVIMTKDSDFIDLVDHLGTPPQVIWLTCGN
VTNRSLRQLLMTALPNALEQLRQGDRIVEISKTFEIT

Download         Length: 354 bp

>T181886 NZ_CP086197:989900-990823 [Xanthomonas oryzae]
ATGAACGAACCTGACAAGAGCAGGCGCACTGTTGCCGCGTCGGTTCGCGCCCGGCTGCTCAACAAGGCCCGCGCCGAAAG
ACTCGACTTCAACCTGCTGCTGACCCGCTACGCGCTGGAGCGCGTCCTTTACCGCCTGAGCGTTTCGGAGCAGCAGGGTC
AATTCTTGCTCAAAGGTGCGCTGCTGTTCGACATCTGGTTCGACATACCGCATCGCCCGACGCACGATGCCGACCTGCTG
GGCTTCGGCTCCACCGAGATCCCACATCTGGAAGACCTGTTCCGCAGAATCAGTCAAATCGCCAGCGATGACGGCATCGT
GTTTCAGGCCGACAGCGTGAAGGCCGCCGAAATCCGCAAGGAGGCCAACTACGCGGGCGTCCGTGTGACGATGATCGGCC
TGCTCGATGGCGCGCGCTGCACGGTGCAGATCGACATCGGTTTCGGCGACGCCGTGACGCCCGGCCCGGACAACGTGCAG
TACCCAGTCATCCTCGACGGCATGCCGCAGCCGCAACTGCGGGTCTATCCCCGCTACACCGTGGTCGCCGAAAAGCTGGA
AGCGATGGTCAAGCTCGGCATCCTCAACAGCCGGATGAAGGACTACTTCGACCTCTGGGTTCTCGCCGGACATTCCGACT
TCGACGGTGCGGTGCTGGCCACGGCCATTCGCGCCACGTTCGAGTGCAGGGGTACGGCCATCCCACCCGGCGCGCCGCTG
GGCCTCACCGATGAGTTCGGCCTGGACGAGCAGAAGACAAAGCAGTGGCAGGCGTTCCTGCGCAAGAACACCTTGGAGCC
GATGCCGCTGACCACGGTGATCGAAGCGCTGCGCGAATTCGTGCTGCCCGTGCTGGCCGCGCTCGCGGCAGGCGAAGGTT
TCGACCGCCAGTGGCGCGCGGGCGCGGGATGGGATGCGGCCTGA

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8357.70 Da        Isoelectric Point: 4.3821

>AT181886 WP_212661752.1 NZ_CP064923:c3081168-3080938 [Acaryochloris marina S15]
MNATNLLTRITQVPGQCGGRPCIRGMRIRVSDILEMLAENVTTAEILDDFPDLELADIQACLLFAARRTDVPQLTA

Download         Length: 231 bp

>AT181886 NZ_CP086197:989304-989903 [Xanthomonas oryzae]
ATGGACACGACCGTCGACAAGCTGCTGGAGCTGGTGCGCACGCGGGGACTTCTGCGCCCGCACGATCTGGCCCCACTGGG
CATCCCACGGGTGGCCCTGACGCGGGCCGTTCGGCGCGGGCAACTGGAGCGCGTCGGGCGCGGCCTGTACGGCCTGGTGG
CGCGTCCGGTGTCGGCCCACGGCACGCTGGCCGAAGTCGCGCGCCGCGTGCCCAAGGGCGTGGTCTGCCTGCTGTCGGCG
CTGCGCGTCCACGACCTGACGACCCAGGCCCCGTTCGAGGTGTGGCTGGCCATCGACAACAAGGCCGCTGCCCCGAAGCT
GGACTACCCGCCGCTACGTCTCGTGCGCTTCTCCGGGCCGGCGCTGAGCGAGGGCGTCGAGGAACACGTTGTTGATGGTG
TGCCCGTCCACGTGACCAGCGTCGCCAAGACCGTGGCCGACTGCTTCAAGTACCGCAACAAGATCGGCATCGACGTGGCG
CTGGAAGCGCTGCGCGAGGCGTGGGTTGCCCGGCGCATGACCAGCGACGAGATCTGGCACTACGCCAAGATCGACCGCGT
CGCCAACGTGATGCGTCCCTATCTGGAGAGCCTGGCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References