Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) TacT2-ataR/DUF1778(antitoxin)
Location 3075283..3076036 Replicon chromosome
Accession NZ_CP064908
Organism Synechococcus sp. CBW1107

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag I1E95_RS15995 Protein ID WP_197163944.1
Coordinates 3075551..3076036 (+) Length 162 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag I1E95_RS15990 Protein ID WP_197163942.1
Coordinates 3075283..3075564 (+) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I1E95_RS15980 3072014..3072934 - 921 WP_197163938.1 hypothetical protein -
I1E95_RS15985 3073105..3075243 + 2139 WP_197163940.1 WYL domain-containing protein -
I1E95_RS15990 3075283..3075564 + 282 WP_197163942.1 DUF1778 domain-containing protein Antitoxin
I1E95_RS15995 3075551..3076036 + 486 WP_197163944.1 GNAT family N-acetyltransferase Toxin
I1E95_RS16000 3076251..3076451 - 201 WP_197163946.1 hypothetical protein -
I1E95_RS16005 3076704..3077321 - 618 WP_197163948.1 hypothetical protein -
I1E95_RS16010 3077494..3078003 + 510 WP_197163950.1 hypothetical protein -
I1E95_RS16015 3078029..3078226 + 198 WP_197163952.1 hypothetical protein -
I1E95_RS16020 3078204..3078608 - 405 WP_197163954.1 DNA-binding protein -
I1E95_RS16025 3078834..3080201 + 1368 WP_197163956.1 IS21 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(74-144)

Antitoxin

Vibrio phage ICP1, Orf50

(7-72)


Sequences

Toxin        


Download         Length: 162 a.a.        Molecular weight: 17271.96 Da        Isoelectric Point: 9.4034

>T181881 WP_197163944.1 NZ_CP064908:3075551-3076036 [Synechococcus sp. CBW1107]
MRPPEPLGPQHQLEGFDCGNAALNRWLQQRALANERQGVSRTVVLCPDEGNAVIAYACLSAGAIVLAEVPGALRRNMPDP
LPVVVLGRLAVDRRHQGQGLGRALVADALRRSLAARRLIGARALLVHAIDEQAAAFYRSLGFRPSPLSASTLMLQLSEPA
D

Download         Length: 486 bp

>T181881 NZ_CP086196:c1214985-1214062 [Xanthomonas oryzae]
ATGAACGAACCTGACAAGAGCAGGCGCACTGTTGCCGCGTCGGTTCGCGCCCGGCTGCTCAACAAGGCCCGCGCCGAAAG
ACTCGACTTCAACCTGCTGCTGACCCGCTACGCGCTGGAGCGCGTCCTTTACCGCCTGAGCGTTTCGGAGCAGCAGGGTC
AATTCTTGCTCAAAGGTGCGCTGCTGTTCGACATCTGGTTCGACATACCGCATCGCCCGACGCACGATGCCGACCTGCTG
GGCTTCGGCTCCACCGAGATCCCACATCTGGAAGACCTGTTCCGCAGAATCAGTCAAATCGCCAGCGATGACGGCATCGT
GTTTCAGGCCGACAGCGTGAAGGCCGCCGAAATCCGCAAGGAGGCCAACTACGCGGGCGTCCGTGTGACGATGATCGGCC
TGCTCGATGGCGCGCGCTGCACGGTGCAGATCGACATCGGTTTCGGCGACGCCGTGACGCCCGGCCCGGACAACGTGCAG
TACCCAGTCATCCTCGACGGCATGCCGCAGCCGCAACTGCGGGTCTATCCCCGCTACACCGTGGTCGCCGAAAAGCTGGA
AGCGATGGTCAAGCTCGGCATCCTCAACAGCCGGATGAAGGACTACTTCGACCTCTGGGTTCTCGCCGGACATTCCGACT
TCGACGGTGCGGTGCTGGCCACGGCCATTCGCGCCACGTTCGAGTGCAGGGGTACGGCCATCCCACCCGGCGCGCCGCTG
GGCCTCACCGATGAGTTCGGCCTGGACGAGCAGAAGACAAAGCAGTGGCAGGCGTTCCTGCGCAAGAACACCTTGGAGCC
GATGCCGCTGACCACGGTGATCGAAGCGCTGCGCGAATTCGTGCTGCCCGTGCTGGCCGCGCTCGCGGCAGGCGAAGGTT
TCGACCGCCAGTGGCGCGCGGGCGCGGGATGGGATGCGGCCTGA

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10297.61 Da        Isoelectric Point: 4.3184

>AT181881 WP_197163942.1 NZ_CP064908:3075283-3075564 [Synechococcus sp. CBW1107]
MARDQVLQLRASAEQRQLIDQAAAAEGISRTEFILRSCQERARDVLLDRTLFSLTPEQTTALLVDLEDSGAAAQDQASID
RLLELPLPWHAPA

Download         Length: 282 bp

>AT181881 NZ_CP086196:c1215581-1214982 [Xanthomonas oryzae]
ATGGACACGACCGTCGACAAGCTGCTGGAGCTGGTGCGCACGCGGGGACTTCTGCGCCCGCACGATCTGGCCCCACTGGG
CATCCCACGGGTGGCCCTGACGCGGGCCGTTCGGCGCGGGCAACTGGAGCGCGTCGGGCGCGGCCTGTACGGCCTGGTGG
CGCGTCCGGTGTCGGCCCACGGCACGCTGGCCGAAGTCGCGCGCCGCGTGCCCAAGGGCGTGGTCTGCCTGCTGTCGGCG
CTGCGCGTCCACGACCTGACGACCCAGGCCCCGTTCGAGGTGTGGCTGGCCATCGACAACAAGGCCGCTGCCCCGAAGCT
GGACTACCCGCCGCTACGTCTCGTGCGCTTCTCCGGGCCGGCGCTGAGCGAGGGCGTCGAGGAACACGTTGTTGATGGTG
TGCCCGTCCACGTGACCAGCGTCGCCAAGACCGTGGCCGACTGCTTCAAGTACCGCAACAAGATCGGCATCGACGTGGCG
CTGGAAGCGCTGCGCGAGGCGTGGGTTGCCCGGCGCATGACCAGCGACGAGATCTGGCACTACGCCAAGATCGACCGCGT
CGCCAACGTGATGCGTCCCTATCTGGAGAGCCTGGCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References