Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1-Phd
Location 2864244..2864914 Replicon chromosome
Accession NZ_CP064908
Organism Synechococcus sp. CBW1107

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag I1E95_RS14995 Protein ID WP_197163576.1
Coordinates 2864244..2864663 (-) Length 140 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag I1E95_RS15000 Protein ID WP_197163578.1
Coordinates 2864654..2864914 (-) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I1E95_RS14940 2859750..2859929 - 180 WP_197163557.1 hypothetical protein -
I1E95_RS14945 2860134..2860751 + 618 WP_197163559.1 Uma2 family endonuclease -
I1E95_RS14950 2860690..2861070 - 381 WP_197163561.1 transposase family protein -
I1E95_RS14955 2861234..2861437 + 204 WP_197163563.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein -
I1E95_RS14960 2861434..2861823 + 390 WP_197163565.1 type II toxin-antitoxin system VapC family toxin -
I1E95_RS14965 2862072..2862326 + 255 WP_197163567.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
I1E95_RS14970 2862335..2862745 + 411 WP_197163569.1 type II toxin-antitoxin system VapC family toxin -
I1E95_RS14975 2862765..2863175 - 411 Protein_2941 N-acetylmuramoyl-L-alanine amidase -
I1E95_RS14980 2863138..2863533 + 396 WP_197163571.1 hypothetical protein -
I1E95_RS14985 2863610..2863930 - 321 WP_197163572.1 hypothetical protein -
I1E95_RS14990 2863927..2864163 - 237 WP_197163574.1 hypothetical protein -
I1E95_RS14995 2864244..2864663 - 420 WP_197163576.1 type II toxin-antitoxin system VapC family toxin Toxin
I1E95_RS15000 2864654..2864914 - 261 WP_197163578.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
I1E95_RS15005 2865057..2865941 - 885 WP_197163579.1 N-acetylmuramoyl-L-alanine amidase -
I1E95_RS15010 2866020..2866253 + 234 WP_197163581.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein -
I1E95_RS15015 2866253..2866639 + 387 WP_197163589.1 PIN domain-containing protein -
I1E95_RS15020 2866690..2867029 + 340 Protein_2950 HEPN domain-containing protein -
I1E95_RS15025 2866947..2867132 + 186 WP_197167589.1 hypothetical protein -
I1E95_RS15030 2867244..2867714 - 471 WP_197163591.1 hypothetical protein -
I1E95_RS15035 2867790..2868812 - 1023 WP_197167561.1 GDP-L-fucose synthase -
I1E95_RS15040 2868817..2869905 - 1089 WP_197163599.1 GDP-mannose 4,6-dehydratase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-118)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(4-73)


Sequences

Toxin        


Download         Length: 140 a.a.        Molecular weight: 15472.68 Da        Isoelectric Point: 7.1692

>T181879 WP_197163576.1 NZ_CP064908:c2864663-2864244 [Synechococcus sp. CBW1107]
VFLIDTVVLSELRRRQRDPGVVAWIGSQRQEDCFLSVVSIGEIERGIARKRTTDSRFAQQLAGWLDQLLRLYGDRLLPVD
VGVARRWGQLSAELGHDGADLLIAATALERGLTVVTRNLRHFTPTGVQTLDPWSPEAGI

Download         Length: 420 bp

>T181879 NZ_CP086195:c4807829-4807548 [Xanthomonas oryzae]
ATGATCAGGAGCTTTATCGACAAGGACGCCGAAAAGATCTGGCTGGGTGAGCGTTCCCGCCGGTTGCCTGCCGACATCCA
ATTGGTCGCGCGCCGCAAGTTGCGCATGCTCAATGCCGCCGCGCATCTCGACGATCTGCGGATCCCGCCCGCCAACCGGC
TGGAAGCGTTGAAGGGCCAGCAGCGCGGCCAGTACAGCATCCGGATCAACGATCAATGGCGCATCTGCTTCCGATGGATG
GAAGGCGATGTGGTCCAGGTCGAAATCGTCGATTACCACTGA

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9704.94 Da        Isoelectric Point: 4.5881

>AT181879 WP_197163578.1 NZ_CP064908:c2864914-2864654 [Synechococcus sp. CBW1107]
MDAVWTLQDAKNRFSAVVDAAARGEPQKVTRRGTWVSVVLSAEEYERLRRLDQANAPSLAELLLQMPQDDESFERLPLAA
RDFPCS

Download         Length: 261 bp

>AT181879 NZ_CP086195:c4807530-4807240 [Xanthomonas oryzae]
ATGACGGTCCTACCCAATATCCATCCTGGCGACATTCTGCTTGAGGAGTTTCTCGAGCCTCTGGGCATCAGCCAGAACGC
ACTGGCACGCGCCACCGGCGTCCCGCCGCGCCGTATCAACGAAATCGTGCTGGGCAAGCGCGGCATCACTGCCGACACTG
CCGTGCGTCTGGCCGCCGCGTTGGGCACCTCCGAGCGCTTCTGGCTGGGCCTGCAGGCCGACTACGAGCTGGAACAGGCG
CATCGCGCGCTGGGCGATTTGCCGGCACGGATCAAGCGGCTGGCGGCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References